The Bioenergetics Core presently includes an XFe 24 Extracellular Flux Analyzer (Seahorse Biosciences, North Billerica, MA). The instrument is accessible to the investigators of the School of Medicine. Interested investigators or their trainees will be provided training in using the instrument and analyzing the data.
XFe 24 Extracellular Flux Analyzer simultaneously measures the two major energy producing pathways of the cell, mitochondrial respiration and glycolysis, in a microplate, in real-time. The XFe24 Analyzers, stress test kits, and reagents can determine in vitro oxygen consumption, glycolysis, CO2, mitochondrial dysfunction, and fatty acid oxidation.Read More
The fast and sensitive measurement of cellular bioenergetics with XF is label-free, enabling time-resolved analysis and the reuse of the cells. XF assays provide increased throughput in a drug discovery format. By incorporating low-cost, disposable fluorescent optical sensors, multiplexed fiber optics and highly integrated electronic components - XFe instruments offer scientists the ability to:
Prasad V.G. Katakam, M.D., Ph.D.
Assistant Professor of Pharmacology
Tulane University Schoo of Medicine
1430 Tulane Avenue, SL-83, Room 3554C