Publications

 
2016-present (* Corresponding author)

Lu Yang, Qian Zhang, Hong Liu* (2021) SET levels contributes to cohesion fatigue.  Mol Biol Cell (doi/10.1091/mbc.E20-12-0778)             

Yujue Chen, Qian Zhang, Zhen Teng, and Hong Liu* (2021) Centromeric Transcription Maintains Centromeric Cohesion in Human Cells. J Cell Biol. 2021 July 5;220(7) e202008146. doi: 10.1083/jcb.202008146.

Zhang Q, Hu L, Chen Y, Tian W*, and Liu H* (2020) Multisite Phosphorylation Determines the Formation of Ska-Ndc80 Macro-complexes That Are Essential for Chromosome Segregation during Mitosis. Mol Biol Cell. 2020 Aug 1;31(17):1892-190.

Zhang Q, Liu H* (2020) Functioning mechanisms of Shugoshin-1 in centromeric cohesion during mitosis. Essays Biochem. 2020 May 26;. doi: 10.1042/EBC20190077.

Qu Q, Zhang Q, Yang L, Chen Y, Liu H* (2019) SET binding to Sgo1 inhibits Sgo1-cohesin interactions and promotes chromosome segregation. J Cell Biol. 2019 Aug 5;218(8):2514-2528.

Hu L, Huang H, Hei M, Yang Y, Li S, Liu Y, Dou Z, Wu M, Li J, Wang GZ, Yao X, Liu H, He X, Tian W (2019) Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Res. 2019 Jan 10;47(1):468-479.

Palozola KC, Liu H, Nicetto D, Zaret KS (2018) Low-Level, Global Transcription during Mitosis and Dynamic Gene Reactivation during Mitotic Exit. Cold Spring Harb Symp Quant Biol. 2018 Jan 18. pii: 034280.

Zhang Q, Chen Y, Yang L, Liu H* (2018) Multitasking Ska in Chromosome Segregation: Its Distinct Pools Might Specify Various Functions. Bioessays, 2018 Jan 23. doi: 10.1002/bies.201700176. (Invited review)

Palozola KC, Donahue G, Liu H, Grant GR, Becker JS, Cote A, Yu H, Raj A, Zaret KS. (2017) . Mitotic transcription and waves of gene reactivation during mitotic exit. Science, 2017 Oct 6;358(6359):119-122

Zhang Q, Sivakumar S, Chen Y, Gao H, Yang L, Yuan Z, Yu H, and Liu H*  (2017) Ska3 Phosphorylated by Cdk1 Binds Ndc80 and Recruits Ska to Kinetochores to Promote Mitotic Progression. Curr Biol 27(10):1477-1484.

Liu H* (2016) Insights into Centromeric Transcription in Mitosis. I. 2016;7(1):21-5. Transcription. 2016;7(1):21-5. (Invited review)

Liu, H* (2016) Linking lncRNA to genomic stability. Sci China Life Sci. 2016 Mar;59(3):328-9. (Invited review)

 

Before 2016

Liu, H, Qu, Q., Warrington R., Rice, A., Cheng N., and Yu, H., (2015) Mitotic Transcription Installs Sgo1 at centromeres to Coordinate Chromosome Segregation. Molecular Cell, 59(3), 426-436.

Hara, K., Zheng, G., Qu, Q., Liu, H., Ouyang, Z., Chen, Z., Tomchick, D.R., Yu, H. (2014) Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat Struct Mol Biol, 21, 864-870.

McKnight K., Liu H., Wang, Y. (2014). Replicative stress induces intragenic transcription of the ASE1 gene that negatively regulates Ase1 activity. Curr Biol 24, 1101-1106.

Liu, H., Jia, L., and Yu, H. (2013). Phospho-H2A and cohesin specify distinct tension-regulated Sgo1 pools at kinetochores and inner centromeres. Curr Biol 23, 1927-1933.

(Comment in:  Chromosome segregation: Learning to let go. Curr Biol. 2013 Oct 7;23(19):R883-5.)

Liu, H., Rankin, S., and Yu, H. (2013). Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis. Nat Cell Biol 15, 40-49.

Jin, F.*, Liu, H.*, Li, P., Yu, H.G., and Wang, Y. (2012). Loss of function of the Cik1/Kar3 motor complex results in chromosomes with syntelic attachment that are sensed by the tension checkpoint. PLoS Genet 8, e1002492. (* Co-first author)

Liu, H.*, Jin, F*., Liang, F., Tian, X., and Wang, Y. (2011). The Cik1/Kar3 motor complex is required for the proper kinetochore-microtubule interaction after stressful DNA replication. Genetics 187, 397-407. (* Co-first author)

Liu, H., and Yu, H. (2010). Mad revival of cancer. Cell Res 20, 394-396. (Review)

Liang, F., Jin, F., Liu, H., and Wang, Y. (2009). The molecular function of the yeast polo-like kinase Cdc5 in Cdc14 release during early anaphase. Mol Biol Cell 20, 3671-3679.

Jin, F., Liu, H., Liang, F., Rizkallah, R., Hurt, M.M., and Wang, Y. (2008). Temporal control of the dephosphorylation of Cdk substrates by mitotic exit pathways in budding yeast. Proc Natl Acad Sci U S A 105, 16177-16182.

Liu, H., Liang, F., Jin, F., and Wang, Y. (2008). The coordination of centromere replication, spindle formation, and kinetochore-microtubule interaction in budding yeast. PLoS Genet 4, e1000262.

Liu, H., and Wang, Y. (2006). The function and regulation of budding yeast Swe1  in response to interrupted DNA synthesis. Mol Biol Cell 17, 2746-275.