BMS PhD with a Concentration in Biomedical Informatics

PhD BIMI

 

The Division of Biomedical Informatics and Genomics offers an interdisciplinary PhD concentration in Biomedical Informatics (BIMI) within the School of Medicine Biomedical Sciences Program. The division reaches across medical disciplines to provide clinical insights into the underlying mechanisms of disease, assist in the discovery of novel therapeutic treatments, and point to new lines of scientific and medical inquiry for improving human health.

Our graduates may find careers in:

  • Research and teaching facilities at universities and medical institutions.
  • Private research and (bio)-technology companies such as Microsoft, Google, and several in the pharmaceutical industry.
  • Biomedical-related consulting firms.

In the BIMI concentration program, students will learn to effectively use conventional, electronic health/medical, and big data for biomedical and clinical research to improve human health.

Program objectives include:

  • Offering a research-based professional PhD program that prepares its graduates to perform as leaders in the critical area of biomedical informatics.
  • Developing an interdisciplinary program that builds on the strengths of students from diverse backgrounds in fields such as data science, bioinformatics, statistical science, biomedical engineering, computing, public health, and medicine.
  • Preparing students to participate in research programs and apply their knowledge in academia, clinical healthcare, public health, and other industries.
  • Preparing students to seek external funding that will support and advance the mission and educational activities of the biomedical informatics program.

The curriculum is designed to include the following high-level competency areas:

  • Biomedically-related courses 
    • Principals of Public Health Informatics
    • Biomedical Imaging and Process
    • Advanced Bioinformatics
  • Data science-related courses
    • Introduction to Data Science
    • Data Science with Cloud Computing
    • Advanced-Data Science Analytic Techniques
    • Big data-related courses
  • Other courses in Biomedical Engineering, Biochemistry and Molecular Biology

The first two years are generally devoted to coursework and research. Subsequent years focus on independent research that culminates in a dissertation. Students accepted into the BMS BIMI concentration are required to join the faculty in the Division of Biomedical Informatics and Genomics, however, PhD students may consider selecting faculty members outside of the Division for committee members or co-mentors with the approval of the Division Chief.

For more information about the curriculum, please visit the corresponding Interdisciplinary PhD in BMS page.

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Curriculum & Course Descriptions

Must complete 48 credit hours to earn a PhD at Tulane University.

  • Elements in Biomedical Informatics: BIMI 6100 Fall, 4 credit hours

    The objective of this course is to teach graduate students the necessary backgrounds of biomedical informatics with computer applications in biomedicine and health care. The biomedical data, their acquisition, storage, ethics, and use in biomedical decision-making for probabilistic clinical reasoning will be introduced. The basic underlying cognitive science issues will be studied in which information is processed by the human mind and biomedical informatics. Students will acquire essential concepts for biomedical computing, system design, and engineering in health care. The application of natural language, text processing, and imaging structures in biomedicine will be discussed. Finally, the challenges associated with technology assessment and the evaluation of clinical information systems, imaging systems in radiology, computers in medical education, and health care financing are introduced. Student presentation/discussion sessions following each block will allow students to present (4 times) and discuss the principles and the applications of the latest biomedical informatics technologies.
     

  • Introduction to Data Science for Biomedical Informatics: BIMI 6200, Fall, 3 credit hours

    Data science has become a central element of both scientific research and industry. The objective of this course is to teach graduate students the necessary backgrounds of data science biomedical informatics with MySQL, R, Python, and MATLAB programs. The overview of biomedical data science- introduction to database, biological database, data storage, and biomedical data showcase will be introduced. The basic underlying data structures, algorithms, and inference from a biomedical informatics point of view will be studied. Students are expected to become comfortable with SQL, R, Python, and MATLAB programming along with the structure and syntax of functions. Advanced coding skills, techniques, ideas, and new packages (library) management will be accomplished practically. Exploratory analysis, data visualization, report prosecution techniques and data science and analytics in health care will be discussed. Finally, necessary concepts of imaging with multi-omics data integration are introduced. Student presentation/discussion sessions following each block will allow students to present (4 times) and discuss the problem of programming.
     

  • Fundamentals of Data Analytics: BIMI 6300, Spring, 3 credit hours

    The objective of this course is to teach graduate students to understand the current state of multivariate and multi-view statistical analysis in an age of complex biomedical data. Overview of multivariate and multi-view data will be addressed. The basic underlying linear regression (e.g., multivariable, multivariate, logistic, and ridge recession) will be studied and practiced with biomedical data. Sparse linear models along with the elastic net, linear dimensionality reduction methods (supervised and unsupervised), linear discriminate analysis, and linear cluster analysis will be discussed with practical applications. As advanced tools, adaptive basis function models, graphical models, artificial neural networks, penalized multivariate analysis, and fusion-based approaches will be introduced to evaluate biomedical data. Finally, students will learn how to use R /Python as a tool and apply the multivariate and multi-view data processing techniques to solve some biomedical problems such as gene-gene interaction, prediction, classification, and multi-omics integration analysis. Student presentation/discussion sessions following each block will allow students to present (4 times) and discuss the principles and the applications of the latest multivariate technologies.
     

  • Health Informatics: BIMI 6400, Spring, 3 credit hours

    The goal of this course is to teach graduate students for the increasing necessity for computation in modern health informatics research. Foundations of Health informatics, Health informatics database, and theoretical foundations of health informatics will be discussed. Models, Theories and Research for program evaluation, Technical Infrastructure to support healthcare, administrative application in Healthcare, clinical decision support systems in healthcare and public health informatics will be studied. The engaged ePatient, social media tools for practice and education, personal health records, and mHeal will be introduced. Finally, Managing the life cycle of a health information system, usability, standards, safety, analytics, governance structures, legal and regulatory issues in health informatics will be studied.

  • Statistical Machine and Deep Learning in Biomedical Practice: BIMI 7100, Fall, 3 credit hours

    The objective of this course is to teach graduate students for a comprehensive understanding of automatically detectable patterns in data, and then to use the identified patterns to predict future data. A background of probability theory, functional analysis, and overview of statistical machine learning with data representation and features engineering will be launched. A popular machine learning tool for classification and regression, support vector machine and its variants will be studied and practiced with biomedical data. The notion of positive definite kernel and kernel-based methods will be discussed with real-world applications. Nonlinear dimensionality reduction techniques, including manifold learning (t- SNE and UMAP) will be introduced and evaluated in Biomedical data. Principles of Bayesian statistics, Gaussian processes, Markova and hidden Markova models, and Markov random fields will be discussed with applications. Deep neural networks-based learning approaches and adversarial learning approaches will be considered for biomedical data. Finally, students will learn how to use Python as a tool and apply machine learning, and deep learning techniques to solve some real-world biomedical problems. Student presentation/discussion sessions following each block will allow students to present (4 times) and discuss the principles and the applications of the latest multivariate technologies.
     

  • Biomedical Informatics Workshop: BIMI 7210, Fall & Spring, 1 credit hours

    The Biomedical Informatics Workshop is designed to promote reading, writing, oral presentation skills, and critical analysis of biomedical data, and research related to are a key tool for critically appraising articles and keeping up to date with the current literature. BIMI 7210 Workshop I - IV (1 credit hour) allows credit for participation in these journal clubs.

  • Biomedical Informatics Research Methods: BIMI 7220, Fall, 4 credit hours

    The Biomedical Informatics Workshop is designed to promote reading, writing, oral presentation skills, and critical analysis of biomedical data, and research related to are a key tool for critically appraising articles and keeping up to date with the current literature. BIMI 7210 Workshop I - IV (1 credit hour) allows credit for participation in these journal clubs.

  • Biomedical Informatics Research Methods: BIMI 7230, Spring, 2 credit hours

    The Biomedical Informatics Workshop is designed to promote reading, writing, oral presentation skills, and critical analysis of biomedical data, and research related to are a key tool for critically appraising articles and keeping up to date with the current literature. BIMI 7210 Workshop I - IV (1 credit hour) allows credit for participation in these journal clubs.

  • Genomic Sequence and Omics Data Analysis: BIMI 7500, Spring, 3 credit hours

    The objective of this course is to teach graduate students to understand why big data are assuming a crucial role in Biomedical Informatics. Big data overview, big data in data science, and big data in biomedical informatics will be addressed. Details of big data visualization tools and compressive results interpretation will be introduced and performed. Fundamental and advanced (machine and deep learning) big data analytics approaches will be studied for functional applications. The typical use such as disease privation, multi-omics, medical imaging, and brain imaging, will be focused on understanding the efficiency of Big data. Finally, the audience will discover Big data management challenges, technologies, and leadership skills. Student presentation/discussion sessions following each block will allow students to present (4 times) and discuss the principles and the applications of the latest big data technologies.

  • Special Topics: BIMI 7980, Fall & Spring, 1-6 credit hours

    The Special topics course as designed by visiting or permanent faculty. For description, consult the department. Course may be repeated up to unlimited credit hours under separate titles.

  • Independent Study: BIMI 7990, Fall & Spring, 1-6 credit hours

    The first two years are generally devoted to coursework and research. Subsequent years focus on independent research that culminates in a dissertation. Students accepted into the BMS BMI track are required to join faculty in the Division of Biomedical Informatics and Genomics but may consider one of other faculty outside of the Division for committee members or co-mentors (with approval of the Division Chief). BIMI 7990 Directed Independent Study allows credit for independent research under the direction of a mentor or co-mentor in the Division of Biomedical Informatics and Genomics.

  • Research Methodology of Biomedical Informatics: BIMI 8500, Fall & Spring, 2 credit hours

    This course consists of formal oral presentation and critical discussion to familiarize students, postdoctoral fellows, and outside speakers with the innovative research topics and methodology development of biomedical informatics. This course will use the combined format of a journal club as well as a research meeting. Students are required to present a seminar on a currently published peer- reviewed research paper approved by the course director, on a research idea, or on their own research work. The seminar will cover the advanced biomedical informatics topics, including bioinformatics, genome informatics, transcriptomics, metagenomics, metabolomics, proteomics, biomedical imaging, drug repurposing, health informatics and telehealth, public health informatics, etc. Students are required to participate in discussions following the presentation. In the discussion, students may also talk about their concerns regarding research, scientific paper writing, and grant writing with their peers and faculty members.

  • Dissertation Research: BIMI 9990, Fall & Spring, 0 credit hours

    The goal is to develop a deeper understanding of a research field in biomedical informatics and gain capability to design a conceptual framework, conduct data analysis, and write a dissertation proposal. Designation: This course is for graduate students.

Must complete 48 credit hours to earn a PhD at Tulane University

Course

Credit

First Year: Must complete 28 credit hours 

Fall (1st semester)

Elements in Biomedical Informatics 

BIMI 6100

4

Introduction to Data Science for Biomedical Informatics

BIMI 6200

3

Research Methodology of Biomedical Informatics

BIMI 8500

2

BIMI Workshop (Journal Club)

BIMI 7210

1

BIMI Research Methods (4 credits for 2 rotations)

BIMI 7220

4

Responsible Conduct of Research 

INTD 6010

0

 

 

 

Spring (2nd semester)

Health Informatics in Biomedical Informatics

BIMI 6400

3

Human Molecular Genetics

EPID 7810

3

Fundamentals of Data Analytics

BIMI 6300

3

Research Methodology of Biomedical Informatics

BIMI 8500

2

BIMI Research Methods (3rd rotation)

BIMI 7230

2

BIMI Workshop (Journal Club)

BIMI 7210

1

 

 

 

Summer 

Dissertation Research 

BIMI 9990

0

Second Year: Must complete 21 credit hours

Fall (3rd semester)

Statistical Machine and Deep Learning in Biomedical Practice

BIMI 7100

 

3

Research Methodology of Biomedical Informatics 

BIMI 8500

2

BIMI Workshop (Journal Club)

BIMI 7210

1

Independent Study (BIMI 7990) and/or 

Special Topics (BIMI 7980)

BIMI 7990

BIMI 7980

1-6

Electives (minimum 5 credit hours in fall and spring combined)

 

 

 

 

 

Spring (4th semester)

Research Methodology of Biomedical Informatics 

BIMI 8500

2

BIMI Workshop (Journal Club)

BIMI 7210

1

Genomics and Omics Data Analysis 

BIMI 7500

3

Independent Study (BIMI 7990) and/or  

Special Topics (BIMI 7980)

BIMI 7990

BIMI 7980

1-6

Electives (minimum 5 credit hours in fall and spring combined)

 

 

 

 

 

Summer and Beyond

Dissertation Research

BIMI 9990

0

 

Eligibility Criteria

Applicants must:

  • Earn at least a baccalaureate degree (or its equivalent) from an accredited institution of higher education prior to the start of classes
  • Show a strong science coursework foundation
  • Demonstrate English language proficiency through standardized testing, if English is not your native language

Like the Biomedical Sciences (BMS) PhD Admissions Committee, the Biomedical Informatics (BIMI) PhD Admissions Committee conducts a holistic review of the total application, evaluating applicants using indicators of academic excellence and the potential for educational and professional success. This process relies upon the comprehensive assessment of a combination of quantitative and qualitative measures. Holistic review recognizes that an applicant possesses strengths and weaknesses that must be evaluated in relation to one another. This ensures that an applicant is neither accepted nor denied admission based on a single parameter.

Applications for admission will be assessed based on both achievement and potential for success within the broader context of an applicant’s experiences, opportunities, and challenges. Strong applicants will not only possess competitive academic qualifications for admission, but will demonstrate the ability to contribute to the academic environment, complete the graduate degree program, and ultimately aspire to have a successful research career.

Standardized test scores: GRE or MCAT scores are not required but will be evaluated if provided.

A competitive candidate generally has documented evidence of academic excellence as demonstrated by several of the following:

  • GPA of at least 3.0 (on a 4.0 scale) with a strong performance in upper-level courses
  • Progression of academic performance over time
  • Rigorous curriculum in a prior degree program(s)
  • Successful completion of a professional degree(s)
  • Prior research experience
  • Strong communication skills

Additional factors that will be considered as indicators of commitment to the degree program and overall potential for success include, but are not limited to, one or more of the following:

  • Leadership abilities
  • Relevant work experience
  • Focused talents/skills
  • Creativity in problem-solving
  • Educational and personal background
  • Work ethic

 

Application Deadlines

Interdisciplinary PhD applications open on September 1st, 2024 and will close on March 21st, 2025. Priority deadline: December 31st, 2024.  We encourage all applicants to apply early. Admissions are offered on a rolling basis.

 

Information Needed for Application

You will need to enter/upload the following information to submit your application:

  • Enter Biographical Information
  • Upload a resume/CV
  • Upload a personal statement (1-2 pages)
  • Enter academic history from all colleges and universities attended
  • Request that official transcripts be sent to Tulane BMS program, bms@tulane.edu
  • Request three Letters of Recommendation, preferably from academic instructors, or researchers

Your application will be reviewed when the following information is received

  • Official transcripts from all prior colleges or universities.
  • Three letters of recommendation
  • TOEFL score, IELTS score, or other evidence of English proficiency for international applicants (see non-native English speakers below)
  • Evaluated transcripts from an evaluation service for international students (see International Students below).

Note: International applicants whose highest degree is from an international university must have those transcripts evaluated by a service (www.naces.org) and the evaluation must be received before the admissions committee will review your application.

 

Application Fee

There is no application fee.

 

Personal Statement

Your personal statement should describe your purpose in pursuing a doctorate in Biomedical Sciences. Include an explanation of any past research and future research interests, indicating how they are related to your professional goals. Please limit your statement to approximately two pages. You will also be asked to include the names of any Tulane School of Medicine faculty members whose research is of interest.

 

Letters of Recommendation

Applicants must request three letters of recommendation in the application system to be able to submit an application. Letters from professors who know your academic history and capabilities or researchers with whom you have worked are weighted much more heavily than friends, acquaintances or people you know in other capacities. The letters should address your potential to succeed in Tulane’s Graduate Program in Biomedical Sciences.

Recommenders will receive an email with instructions for uploading their letter into the application system along with a rating scale for other attributes.

 

Transcripts

Official transcripts of all undergraduate and graduate study programs are required. Electronic official transcripts from the school or a transcript service are preferred, sent to bms@tulane.edu.  We also accept mailed sealed official transcripts, our institution code is 6178. Photocopied transcripts, faxed transcripts, and student copies of transcripts are not acceptable for admission. Final transcripts indicating receipt of degree must be submitted before the beginning of the incoming semester. Email and postal mail addresses are provided in the application system. International applicants whose highest degree is from an international university must have those transcripts evaluated by a service (www.naces.org) and the evaluation must be received before the admissions committee will review your application.

 

Non-Native English Speakers & International Students

In addition to admissions requirements, applicants who are not native speakers of English must demonstrate an adequate command of the English language. Test of English as a Foreign Language (TOEFL) scores, International English Language Testing System (IELTS) scores, or other evidence of English proficiency are required. For more information about the tests, visit the TOEFL or IELTS website or contact ETS. When requesting ETS to send your score to the Graduate Program in Biomedical Sciences, please use code 6178. English language testing requirements are waived for applicants who have received a degree from an institution where instruction was conducted in English.

For the PhD program, minimum scores of 90 for the TOEFL or 7.0 overall band score for the IELTS are normally required. Applicants with lower scores will be evaluated based on their complete application package. An applicant whose competence in English is unproven or insufficient may be admitted with probationary status on the condition that competence will be proven or improved. The student may be required to prove competence by earning an acceptable score on a test of English. A student who scores below the acceptable level of competence may be required to register for less than a full graduate program and to take English as a Second Language instruction without credit until the ESL program director certifies the student's competence.

The Graduate Program in Biomedical Sciences does not set a specific number of International Students that it will admit each year, but instead weighs the applications of all applicants to select those who are the best qualified. Typically, about one third of our incoming students are international students.

Applicants whose highest degree is from a foreign university must have their credentials evaluated. This evaluation is required even if the primary language of instruction is English and/or the school uses a 4 point grading scale. Applications will not be reviewed without this evaluation.  There are no exceptions. The university will accept evaluations done by any credentialing agency listed on the National Association of Credential Evaluation Services web site (http://www.naces.org). Tulane does not have a preference for which credentialing agency you use.

PhD Students from outside the United States receive the same financial package as U.S. citizens. For more information on tuition scholarships and stipends, see Financial Aid.

 

Tuition & Fees

All PhD students receive a full tuition waiver, paid health insurance, and a stipend $35,000 per year for the entire duration of the program. Students are responsible for all fees assessed during the academic year on a per-semester basis: 

  • Academic Support Services $400 max
  • Student Activities $120
  • Reilly Recreation Center $237
  • Student Health Services $396

For more information on the application process, please visit the corresponding Interdisciplinary PhD in BMS page.

 

 

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