Faculty Publications 2019 - 2020


Section of Pulmonary Diseases, Critical Care and Environmental Medicine

July 1, 2019 - June 30, 2020


Nancy; Zhou, Tong; Gonzalez-Garay, Manuel; Rosas, Ivan; Goldberg, Hilary; Ryter, Stefan; Collard, Harold; El-Chemaly, Souheil; Flaherty, Kevin; Hunninghake, Gary; Lasky, Joseph; Lederer, David; Machado, Roberto; Martinez, Fernando; Noth, Imre; Peters, Elizabeth; Raghu, Ganesh; Choi, Augustine; Garcia, Joe. Low Dose Carbon Monoxide Exposure in Idiopathic Pulmonary Fibrosis Produces a CO Signature Comprised of Oxidative Phosphorylation Genes, Sci Rep. 2019 Oct 15;9(1):14802.
Deskin B, Yin Q, Zhuang Y, Saito S, Shan B, Lasky JA. Inhibition of HDAC6 attenuates tumor growth of Non-Small Cell Lung Cancer. Transl Oncol. 2019 Dec 19;13(2):135-145. PMID: 31865176; PMCID: PMC6926313.

Jamie L Todd, Richard Vinisko, Katey Durham, Yi Liu, Megan L Neely, Robert Overton, Kevin R Flaherty, Imre Noth, L Kristin Newby, Joseph Lasky, Mitchell A Olman, Christian Hesslinger, Thomas Leonard, Scott M Palmer, John A Belperio on behalf of the IPF-PRO Registry investigators. Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort, BMC Pulm Med. 2020 Mar 14;20(1):64.
Qinyan Yin, Nan Deng, Erik Flemington, Joao DeAndrade, Joseph A. Lasky
Assessment of viral RNA in idiopathic pulmonary fibrosis by RNA-seq. BMC Pulm Med. 2020 Apr 3;20(1):81.
Fayez Kheir, Ala Alkahtab, Phillip Daroca, Shigeki Saito, Reynaldo Rampolla, David Weill, Lisa Deithelm, and Joseph A. Lasky. Employing Bronchoscopic Lung Cryobiopsy and a Genomic Classifier in the Multidisciplinary Diagnosis of Diffuse Interstitial Lung Diseases, Chest. 2020 May 25:S0012-3692(20)31499-9.

Ala L. Alkhatib , Jonah Kreniske, Jerry S. Zifodya, Vivian Fonseca, Mohammad Tahboub , Joanna Khatib, Joshua L. Denson, Joseph A. Lasky, Christine M. Bojanowski. Clinical Determinants of Severe CoVID-19 Infections in African Americans, in press, Obesity.

Mackel, J.J. and C. Steele. Host defense mechanisms against Aspergillus fumigatus colonization and invasion and in the lung. Current Opinion in Microbiology 52:14-19 (2019).

Godwin, M.S., K.M. Reeder, J.M. Garth, J.J. Mackel, J.P. Blackburn, Z. Yu, S. Matalon, A.T. Hastie, D.A. Meyers and C. Steele. IL-1RA regulates immunopathogenesis during fungal-associated allergic airway inflammation.  JCI Insight 4 pii: 129055 (2019).

Mackel J.J., J.M. Garth, J.P. Blackburn, M. Jones and C. Steele. 12/15-lipoxygenase deficiency impairs neutrophil granulopoiesis and lung pro-inflammatory responses to Aspergillus fumigatus. Journal of Immunology 204:1849-1858 (2020).

Marks, M., C. Steele, W. Moore, D.A. Meyers, B. Rector, E. Ampleford, E.R Bleecker and A.T. Hastie. Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) and receptors in Type 1, Type 2 and Type 17 Inflammation in Cross-sectional Asthma Study. Thorax 2020 Jun 1 2019-214496 (2020).

Abood RN, McHugh KJ, Rich HE, Ortiz MA, Tobin JM, Ramanan K, Robinson KM, Bomberger JM, Kolls JK, Manni ML, Pociask DA, Alcorn JF.  IL-22-binding protein exacerbates influenza, bacterial super-infection. Mucosal Immunol. 2019 July doi: 10.1038/s41385-019-0188-7.

Eddens T, Elsegeiny W, Ricks D, Goodwin M, Horne WT, Zheng M, Kolls JK. Transcriptomic and Proteomic Approaches to Finding Novel Diagnostic and Immunogenic Candidates in Pneumocystis. mSphere. 2019 Sep 4;4(5). pii: e00488-19. doi: 10.1128/mSphere.00488-19.

Martinu T, McManigle WC, Kelly FL, Nelson ME, Sun J, Zhang HL, Kolls JK, Gowdy KM, Palmer SM. IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease. Transplantation. 2019 Nov;103(11):2264-2274.

Trevejo-Nunez G, Elsegeiny W, Aggor FEY, Tweedle JL, Kaplan Z, Gandhi P, Castillo P, Ferguson A, Alcorn JF, Chen K, Kolls JK, Gaffen SL. Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia. Infect Immun. 2019 Oct 18;87(11).

Castillo-Dela Cruz P, Wanek AG, Kumar P, An X, Elsegeiny W, Horne W, Fitch A, Burr AHP, Gopalakrishna KP, Chen K, Methé BA, Canna SW, Hand TW, Kolls JK.  Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products.  Cell Rep. 2019 Nov 19;29(8):2270-2283.

Henkel M, Partyka J, Gregory AD, Forno E, Cho MH, Eddens T, Tout AR, Salamacha N, Horne W, Rao KS, Wu Y, Alcorn JF, Kostka D, Hirsch R, Celedón JC, Shapiro SD, Kolls JK, Campfield BT. Follistatin-like 1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema. Am J Respir Crit Care Med. 2019.

Shaikh N, Martin JM, Hoberman A, Skae M, Milkovich L, McElheny C, Hickey RW, Gabriel LV, Kearney DH, Majd M, Shalaby-Rana E, Tseng G, Kolls J, Horne W, Huo Z, Shope TR. Biomarkers that differentiate false positive urinalyses from true urinary tract infection. Pediatr Nephrol. 2020 Feb;35(2):321-329

Hebert KD, Mclaughlin N, Galeas-Pena M, Zhang Z, Eddens T, Govero A, Pilewski JM, Kolls JK, Pociask DA.  Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection. Mucosal Immunol. Mucosal Immunol. 2020 Jan;13(1):64-74.

Iwanaga N, Sandquist I, Wanek A, McCombs J, Song K, Kolls JK. Host immunology and rational immunotherapy for carbapenem-resistant Klebsiella pneumoniae infection.  JCI Insight. 2020 Apr 23;5(8):e135591.

Kolls JK, Ray A, Wenzel S. High-Dose Vitamin D3 for Critically Ill Vitamin D-Deficient Patients.  N Engl J Med. 2020 Apr 23;382(17):1669-1670.

Watanabe T, Guan Z, Horie M, Joe B, Juan MU, Buhari H, Hwang D, Kolls JK, Liu M, Keshavjee S, Juvet S, Martinu T. IL-17 Receptor on Donor Cells Regulates Acute and Chronic Lung Allograft Rejection Potentiated by Repeated Endotoxin Inhalations.  J Heart Lung Transplant. 2020 Apr;39(4S):S196

Carsten Schwarz, MD; Sivagurunathan Sutharsan; Ralph Epaud; Ross C Klingsberg; Rainald Fischer; Steven M Rowe; Paul K Audhya; Neil Ahluwalia; Xiaojun You; Thomas J Ferro; Margaret E Duncan; Bote G Bruinsma Tezacaftor/ivacaftor in people with cystic fibrosis who stopped lumacaftor/ivacaftor due to respiratory adverse events. Journal of Cystic Fibrosis, in press.

Heijerman HGM, McKone EF, Downey DG, Van Braeckel E, Rowe SM, Tullis E, Mall MA, Welter JJ, Ramsey BW, McKee CM, Marigowda G, Moskowitz SM, Waltz D, Sosnay PR, Simard C, Ahluwalia N, Xuan F, Zhang Y, Taylor-Cousar JL, McCoy KS; VX17-445-103 Trial Group (Klingsberg). Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.Lancet. 2019 Nov 23;394(10212):1940-1948. doi: 10.1016/S0140-6736(19)32597-8. Epub 2019 Oct 31.

Middleton PG, Mall MA, Dřevínek P, Lands LC, McKone EF, Polineni D, Ramsey BW, Taylor-Cousar JL, Tullis E, Vermeulen F, Marigowda G, McKee CM, Moskowitz SM, Nair N, Savage J, Simard C, Tian S, Waltz D, Xuan F, Rowe SM, Jain R; VX17-445-102 Study Group (Klingsberg). Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele. N Engl J Med. 2019 Nov 7;381(19):1809-1819. doi: 10.1056/NEJMoa1908639. Epub 2019 Oct 31.

Lammi MR, Saketkoo LA, Okpechi SC, Ghonim MA, Wyczechowska D, Bauer N, Pyakurel K, Saito S, deBoisblanc BP, Boulares AH. Microparticles in systemic sclerosis: Potential pro-inflammatory mediators and pulmonary hypertension biomarkers. Respirology. 2019 Jul;24(7):675-683. PubMed PMID: 30747487; PubMed Central PMCID: PMC6579687.

Saito S, Alkhatib A^, Kolls JK, Kondoh Y, Lasky JA. Pharmacotherapy and Adjunctive Treatment for IPF J Thorac Dis. 2019 Sep;11(Suppl 14):S1740-S1754. PMID: 31632751

Bateman ME*, Oakland H*, Oral E, Fisher P, Udemgba, C, Walker, C, Nuss H, Parada NA. Evaluation of a Multidisciplinary Disease Management Program to Improve Asthma Control in an Underserved Patient Population in Louisiana. Population Health Management Jan 2020 PMID32096685

Pritesh, P, Hansen, G, Daignault, S, Kasper, B, Parada, NA Adaptive High Frequency Chest Wall Oscillation (HFCWO) Therapy for Maximum Patient Adherence: A Patient-Centered Approach. Respiratory Therapy 2019; 14: 76-79

Becnel, D. M., Jantz, M. A., & Mehta, H. J. (2020). Endobronchial Valves Are Radiographically Protective during Interstitial Lung Disease Exacerbation. American Journal of Respiratory and Critical Care Medicine, 201(4), e10-e11.

Omballi, M., Fernandez-Bussy, S., Patel, P. P., Jantz, M. A., Becnel, D., Patel, N. M., & Mehta, H. J. (2020, January). Surveillance Imaging After Curative Intent Therapy for Lung Cancer. In Seminars in roentgenology (Vol. 55, No. 1, p. 60).

Liu, Y. Z., S. Saito, G. F. Morris, C. A. Miller, 3rd, J. Li and J. J. Lefante (2019). "Proportions of resting memory T cells and monocytes in blood have prognostic significance in idiopathic pulmonary fibrosis." Genomics 111(6): 1343-1350.

Saito, S., Y. Zhuang, T. Suzuki, Y. Ota, M. Bateman, A. Alkhatib, G.F. Morris, J. Lasky. HDAC8 inhibition ameliorates pulmonary fibrosis. American Journal of Physiology, Lung Cellular and Molecular Physiology 316(1):L175-L186 (2019).

Corriden R, Moshensky A, Bojanowski CM, Meier A, Chien J, Nelson R, Crotty Alexander LE. E-cigarette Use Increases Susceptibility to Bacterial Infection by Impairment of Human Neutrophil Chemotaxis, Phagocytosis and NET Formation. Am J Physiol Cell Physio. 2020. Jan1; 318 (1):C205-214. Epub 2019 Oct 30. PMID: 31664858.

Alasmari F, Crotty Alexander LE, Hammad A, Bojanowski CM, Moshenksy A, Sari Y. Effects of chronic inhalation of electronic cigarette vapor containing nicotine on neurotransmitters in the frontal cortex and striatum of C57BL/6 mice. Front Pharmacol. 2019 Aug 12; 10:885. PMID:31456684

Boddu SA, Bojanowski CM, Lam MT, Advani IN, Scholten EL, Sun Z, Montgrain P, Malhotra A, Jain S, Crotty Alexander LE. Use of E-cigarettes with Conventional Tobacco is Associated with Decreased Sleep Quality in Women. Am J Resp Crit Care. 2019 Dec 1: 200 (11): 1431-1434. PMID: 31314572

Kandikattu, H.K., Venkateshaiah, S.U., Kumar, S. and Mishra, A., 2020. IL-15 immunotherapy is a viable strategy for COVID-19. Cytokine & Growth Factor Reviews. 2020 Jun 6; S1359-6101(20)30098-8.

Kandikattu HK, Venkateshaiah SU, Mishra A. Chronic Pancreatitis and the Development of Pancreatic Cancer. Endocrine, Metabolic & Immune Disorders Drug Targets. 2020 Apr 22. DOI: 10.2174/1871530320666200423095700

Venkateshaiah, S.U., Niranjan, R., Manohar, M., Verma, A.K., Kandikattu, H.K., Lasky, J.A. and Mishra, A. Attenuation of Allergen-, IL-13–, and TGF-α–induced Lung Fibrosis after the Treatment of rIL-15 in Mice. American Journal of Respiratory Cell and Molecular Biology, 2019. 61(1), p.97.

Venkateshaiah SU, Kandikattu HK, Mishra A. Significance of Interleukin (IL)-15 in IgE associated eosinophilic Esophagitis (EoE). International journal of basic and clinical immunology. 2019 Dec 16;2:1.

Manohar, M., Verma, A.K., Singh, G. and Mishra, A., 2020. Eosinophilic pancreatitis: a rare or unexplored disease entity?. Przeglad Gastroenterologiczny, 15(1), p.34.

Masyuko SJ, Page ST, Kinuthia J, Osoti AO, Polyak SJ, Otieno FC, Kibachio JM, Mogaka JN, Temu TM, Zifodya JS, Otedo A, Nakanjako D, Hughes JP, Farquhar C. Metabolic syndrome and 10-year cardiovascular risk among HIV-positive and HIV-negative adults: a cross-sectional study. Medicine 2020; 99:27(e20845)

Choate R, Pasquale CB, Parada NA, Prieto-Centurion V, Mularski RA, Yawn BP. The burden of cough and phlegm in people with COPD: a COPD Patient-Powered Research Network study. Chronic Obstr Pulm Dis. 2020; 7(1): 49-59. doi: http://doi.org/10.15326/jcopdf.7.1.2019.0146

Adnan Majid, MD1, Alvaro Ayala, MD1, Juan Pablo Uribe, MD1, Ramsy Abdelghani, MD1, Priya Patel, MD1, Alex Chee, MD1, Mihir Parikh, MD1, Fayez Kheir MS, MD1. "Protective Strategies in a Simulated Model When Performing Percutaneous Tracheostomies in the COVID-19 Era." Annals of the American Thoracic Society, 0(ja), pp. – 2020.

Listed as a Collaborator on Pubmed

Todd JL, Neely ML, Overton R, Durham K, Gulati M, Huang H, Roman J, Newby LK, Flaherty KR, Vinisko R, Liu Y, Roy J, Schmid R, Strobel B, Hesslinger C, Leonard TB, Noth I, Belperio JA, Palmer SM; IPF-PRO Registry investigators (Lasky JA). Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry. Respir Res. 2019 Oct 22;20(1):227.

O'Brien EC, Hellkamp AS, Neely ML, Swaminathan A, Bender S, Snyder LD, Culver DA, Conoscenti CS, Todd JL, Palmer SM, Leonard TB; IPF-PRO Registry investigators. Disease Severity and Quality of Life in Patients With Idiopathic Pulmonary Fibrosis: A Cross-Sectional Analysis of the IPF-PRO Registry (Lasky JA). Chest. 2020 May;157(5):1188-1198.