Publications

2024

W. Chen

Wu M, Wu S, Chen W, Li YP. The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and disease. Cell Res. 2024 Feb;34(2):101-123. doi: 10.1038/s41422-023-00918-9. Epub 2024 Jan 24. PMID: 38267638

Chen W, Lu Y, Zhang Y, Wu J, McVicar A, Chen Y, Zhu S, Zhu G, Lu Y, Zhang J, McConnell M, Li YP. Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis. Elife. 2024 May 28;13:e95640. doi: 10.7554/eLife.95640.PMID: 3880554.

Zhang Y, Chen H, Wu J, McVicar A, Chen Y, Su J, Li YP, Chen W. Deficiency of Cbfβ in articular cartilage leads to osteoarthritis-like phenotype through Hippo/Yap, TGFβ, and Wnt/β-catenin signaling pathways. Int J Biol Sci. 2024 Mar 11;20(6):1965-1977. doi: 10.7150/ijbs.90250. eCollection 2024.PMID: 38617544

S. DASH:

Srinivas Chava, Nergiz Ekmen, Pauline Ferraris, Yucel Aydin, Krzysztof Moroz, Tong Wu, Swan N Thung and Srikanta Dash. Mechanisms of sorafenib resistance in HCC culture relate to the impaired membrane expression of organic cation transporter-1 (OCT1). Journal of Hepatocellular Carcinoma, 2024;11:1-17.

E. FLEMINGTON:

Ungerleider NA, Roberts C, O'Grady TM, Nguyen TT, Baddoo M, Wang J, Ishaq E, Concha M, Lam M, Bass J, Nguyen TD, Van Otterloo N, Wickramarachchige-Dona N, Wyczechowska D, Morales M, Ma T, Dong Y, Flemington EK. Viral reprogramming of host transcription initiation. Nucleic Acids Res. 2024 May 22;52(9):5016-5032. doi: 10.1093/nar/gkae175. PMID: 38471819.

Abdulnour-Nakhoul SM, Kolls JK, Flemington EK, Ungerleider NA, Nakhoul HN, Song K, Nakhoul NL. Alterations in gene expression and microbiome composition upon calcium-sensing receptor deletion in the mouse esophagus. Am J Physiol Gastrointest Liver Physiol. 2024 Apr 1;326(4):G438-G459. doi: 10.1152/ajpgi.00066.2023. Epub 2024 Jan 9. PMID: 38193195

Magrath JW, Flinchum DA, Hartono AB, Sampath SS, O'Grady TM, Baddoo M, Haoyang L, Xu X, Flemington EK, Lee SB. Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells. Oncogenesis. 2024 Jan 4;13(1):2. doi: 10.1038/s41389-023-00504-z. PMID: 38177125

Ma T, Jin L, Bai S, Liu Z, Wang S, Shen B, Cho Y, Cao S, Sun MJS, Fazli L, Zhang D, Wedderburn C, Zhang DY, Mugon G, Ungerleider N, Baddoo M, Zhang K, Schiavone LH, Burkhardt BR, Fan J, You Z, Flemington EK, Dong X, Dong Y. Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression. J Natl Cancer Inst. 2024 Mar 7;116(3):421-433. doi: 10.1093/jnci/djad215. PMID: 37847647

Safa FM, Rasmussen T, Fontan L, Xia M, Melnick A, Wiestner A, Lobelle-Rich P, Burger JA, Mouawad Y, Safah H, Flemington EK, Saba NS. Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application. Haematologica. 2024 May 1;109(5):1348-1358. doi: 10.3324/haematol.2023.283178. PMID: 37767562

S. LEE:
Magrath, J.W., Goldberg, I.N., Truong, D.D., Hartono, A.B., Sampath, S.S., Jackson, C.E., Ghosh, A., Cardin, D.L., Zhang, H., Ludwig, J.A. and Lee, S.B.* Enzalutamide induces cytotoxicity in desmoplastic small round cell tumor independent of the Androgen Receptor. (2024). Communications Biology, 7, 411 (2024). https://doi.org/10.1038/s42003-024-06003-0. PMID: 38575753.

Magrath, J.W., Sampath, S.S., Flinchum, D.A., Hartono, A.B., Goldberg, I.N., Boehling, J.R., Savkovic, S. and Lee, S.B.* Comprehensive transcriptomic analysis of EWSR1::WT1 targets identifies CDK4/6 inhibitors as an effective therapy for desmoplastic small round cell tumors. (2024). Cancer Research, 84:1426-1442. PMID: 38588409.

YP. LI:

Z. LIN:

J Chen*, Z Lin*, J Fan, B Monzavi-Karbassi, T Kelly, SR Post, L Dai, Z Qin. Identification of new microtubule small-molecule inhibitors and microtubule-associated genes against triple negative breast cancer. 2024 American Journal of Cancer Research. 14 (4), 1545-1560 (*Co-first authors). (Impact factor: 6.2)

J Chen, J Fan, Z Lin, L Dai, Z Qin. Human endogenous retrovirus type K encoded Np9 oncoprotein induces DNA damage response. 2024. Journal of Medical Virology. 96 (3), e29534.

Q Zhang, Y Chen, Z Teng, Z Lin, H Liu. CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis. 2024. Molecular Biology of the Cell. 35 (2), ar18.

K. MOROZ

Assessing Adequacy: A Meta-Analysis of Rapid Onsite Evaluation of Thyroid Nodules. Issa PP, McCarthy C, Hussein M, Albuck AL, Emad E, Shama M, Moroz K, Toraih E, Kandil E. J Surg Res. 2024 Apr;296:523-531. doi: 10.1016/j.jss.2024.01.018. Epub 2024 Feb 7. PMID: 38330678

Survival Outcomes of Medullary Thyroid Cancer With and Without Amyloid Deposition. Toraih E, Hussein M, Anker A, Baah S, Pinion D, Jishu J, Sadakkadulla S, Case M, LaForteza A, Moroz K, Kandil E. Endocr Pract. 2024 Apr;30(4):311-318. doi: 10.1016/j.eprac.2024.01.001. Epub 2024 Jan 5. PMID: 38184237

L. PI

Chunbao Sun, Fanwei Guo, Sreenivasulu Basha, Tian Tian, Brady Jin-Smith, Joshua Barkin, Hanhui Xie, Junmei Zhou, Xiao-Ming Yin, Cheng Ling, Bing Sun, Bryon Petersen, Liya Pi. Extracellular Matrix Protein 1 Binds to Connective Tissue Growth Factor Against Liver Fibrosis and Ductular Reaction. Hepatology Communication, under revision

Chen Zhou, Chunbao Sun, Liya Pi, Chenglong Li. Exploring Degradation of Intrinsically Disordered Protein YAP induced by PROTACs. BioRxiv 2023.09.19.556013; doi: https://doi.org/10.1101/2023.09.19.556013

Journal of Medicinal Chemistry, under revision.

Chen Zhou; Chunbao Sun; Wei Zhou; Tian, Tian; Daniel Schultz; Tong Wu; Mu YU; Lizi Wu; Liya Pi; Chenglong Li. Development of Novel Indole-Based Covalent Inhibitors of TEAD as Potential Anti-liver Cancer Agents. Journal of Medicinal Chemistry, under revision.

Yang Yang, Natacha Jn-Simon, Yonghan He, Chunbao Sun, Peiyi Zhang, Wanyi Hu, Huadong Zeng, Sreenivasulu Basha, Guangrong Zheng, Liya Pi, Daohong Zhou. A BCL-xL/BCL-2 PROTAC effectively clears senescent hepatocytes and prevents NASH-driven hepatocellular carcinoma in mice. Nature Ageing, under revision.

Wei Ni, Mu Yu, Rongqiang Yang, Jennifer W. Li, Xin Zhou, Ozlem Calbay, Liya Pi, Jianrong Lu,Shuang Huang, Lizi Wu. The YAP1-MAML2 fusion drives tumorigenesis and sustains tumor growth. Molecular Therapy Oncology, under revision.

D. TIAN:

Teng Z, Yang L, Zhang Q, Chen Y, Wang X, Zheng Y, Tian A, Tian D, Lin Z, Deng WM, Liu H.Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription. bioRxiv [Preprint]. 2024 May 5:2024.05.03.592391. doi: 10.1101/2024.05.03.592391.PMID: 38746280.

T. WU:

Ma W, Zhang J, Chen W, Liu N, Wu T. The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling. J Exp Clin Cancer Res. 2024 Apr 19;43(1):117. doi: 10.1186/s13046-024-03036-5. PMID: 38641672; PMCID: PMC11027350.

X. XU:

Zhang D, et al. Single-cell RNA sequencing reveals the process of CA19-9 production and dynamics of the immune microenvironment between CA19-9 (+) and CA19-9 (-) PDAC. Chin Med J (Engl). 2024.

Maity S, et al. Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics. Clin Proteomics. 2024

Khadka S, et al. Endogenous glucocorticoids are required for normal macrophage activation and gastric Helicobacter pylori immunity. bioRxiv. 2024

2022

Alghamdi N , Burns C, Valdes R. The Urocortin Peptides: UCN3 Biological Relevance and Laboratory Medicine: Critical Reviews in Clinical Laboratory Sciences, 2022, DOI: 10.1080/10408363.2022.2080175

Alghamdi N , Robinson T, Sharp C, Jortani S . Interpretation of Discordant Results in Maternal/Newborn Dyad Drug Screening, American Journal of Pediatrics. Volume 8, Issue 4, December 2022 , pp. 244-251. doi: 10.11648/j.ajp.20220804.19

Reagan-Steiner SJ. Bhatnagar RB, Martines NS, Milligan C, Gisondo FB, Williams E, Lee L, Estetter, HB, Goldsmith CS, Fair P, Hand J, Richardson KR, Woodworth T, Oduyebo RR, Galang R, Phillips E, Belyaeva E, Yin XM, Meaney-Delman TM, Uyeki DJ, Roberts DJ, Zaki SR. Detection of SARS-CoV-2 in neonatal autopsy tissues and placenta: insights into vertical transmission. Emerging Infectious Diseases, 28(3): 510-517, 2021, doi: 10.3201/eid2803.211735. PMID: 35138244

Belyaeva E, Rubenstein A, Pierson SK, Dalldorf D, Frank D, Lim MS, Fajgenbaum DC, Sheila K Pierson . Bone marrow findings of idiopathic Multicentric Castleman disease: A histopathologic analysis and systematic literature review . Hematol Onco. 2022 Apr;40(2):191-201. doi: 10.1002/hon.2969. Epub 2022 Feb 18.

Liu, FK, Han R, Blair K, Kenst Z, Qin B, Upcin P, Worsdorfer CC, Midkiff J, Mudd E, Belyaeva E, Milligan NS, Dorison T, Wagner N, Bodem J, Dolken BH, Aktas BH, Vander Heide R, Yin XM, Kolls JK, Roy CJ, Rappaport J, Ergun S, Qin X. SARS-CoV-2 infects endothelial cells in vivo and in vitro. Front. Cell. Infect. Micriobiol. 11:701278, Published online July 6, 2021. DOI: 10.3389/fcimb.2021.701278, PMID: 34307198

* Tang CY, Wang H, Zhang Y, Wang Z, Zhu G, McVicar A, Li YP, Chen W. GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways. Int J Biol Sci. 2022 Mar 6;18(6):2392-2405. doi: 10.7150/ijbs.70620. PMID: 35414778; PMCID: PMC8990458.

*Zhang Y, Zuo T, McVicar A, Yang HL, Li YP, Chen W. Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP, TGFβ, and Wnt signaling in articular cartilage formation and osteoarthritis. Bone Research. 2022 Oct 28;10(1):63. PMID: 36307389 PMCID: PMC9616925.

Nebeluk N, Bruno LN, Duke M, Craig R, Love G, Hunt JP, Marr A, Schoen J, Stuke L, Greiffenstein P, Smith AA. Proposed Treatment Algorithm for Invasive Fungal Infections in Trauma Patients. Surg Infect (Larchmt). 2022 Aug;23(6):550-557. doi: 10.1089/sur.2021.325. Epub 2022 Jun 8.PMID: 35675674

Dash S, Koksal AR, Dong L, Koksal AR. Commentary on fibrogenic signals persist in DAA-treated HCV patients after sustained virological response. ExRNA, 2022:4:7 (31March2022). doi:10.21037/exrna-21-33.

Ali Riza Koksal, Nunez Kelly, Paul Thevenot, Kyle Widmer, Leela Nayak^,Martin Moehlen, Ari Cohen and Srikanta Dash. Impaired autophagy response in hepatocellular carcinoma enriches glypican-3 in exosomes, not in the microvesicles. Journal of Hepatocellular Carcinoma, 2022; Sept 7,9:959-972.

Safa F, Rasmussen T, Lobelle-Rich P, Collier S, Milligan N, Schmeig J, Schmid J, Wiewiorowski C, Totaro D, Brown TC, Satyavarapu I, Badoo M, Ungerleider N, Flemington EK, Safah H, Saba NS. Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo. eJHaem. 2022 Sep 20;3(4):1326-1329. doi: 10.1002/jha2.580.

Wang Y, Ungerleider N, Hoffman BA, Kara M, Farrell PJ, Flemington EK, Lee N, Tibbetts SA. A Polymorphism in the Epstein-Barr Virus EBER2 Noncoding RNA Drives In Vivo Expansion of Latently Infected B Cells. mBio. 2022 Jun 28;13(3):e0083622. doi: 10.1128/mbio.00836-22.

Melnik LI, Guha S, Ghimire J, Smither AR, Beddingfield BJ, Hoffmann AR, Sun L, Ungerleider NA, Baddoo MC, Flemington EK, Gallaher WR, Wimley WC, Garry RF. Ebola virus delta peptide is an enterotoxin. Cell Rep. 2022 Jan 4;38(1):110172. doi: 10.1016/j.celrep.2021.110172.

Stahl M, Li Q, Lynch K, Koletzko S, Mehta P, Gragert L, Norris J, Aronsson C, Lindfors K, Kurppa K, Ilonen J, Krischer J, Alkolkar B, She J, Ziegler A, Toppari J, Rewers M, Agardh D, Hagopian, W, Liu E, and the TEDDY Study Group. (2022) Incidence of Pediatric Celiac Disease Varies by Region. American Journal of Gastroenterology. 2022 Oct 10. DOI: 10.14309/ajg.0000000000002056

Olson T, Frost BF, Duke JL, Dribus M, Xie HM, Prudowsky ZD, Furutani E, Gudera J, Shah Y, Ferriola D, Xu E, He M, Zheng S, Nijim S, Lin P, Xu C, Nakano T, Oved JH, Carreno BM, Lee SJ, Monos DS, Shimamura A, Bertuch AA, Gragert L, Spellman SR, Babushok D (2022) Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities. JCI Insight 2022 Oct 11;e163040. DOI: 10.1172/jci.insight.163040.

Gragert L , Kadatz M, Alcorn J, Stewart D, Gill J, Liwski R, Gebel H, Gill J, Lan J. (2022) ABO-Adjusted Calculated Panel Reactive Antibody (cPRA): A Unified Metric for Immunologic Compatibility in Kidney Transplantation. American Journal of Transplantation doi: 10.1111/ajt.17175.

Rushakoff J, Gragert L, Pando MJ, Huang E, Stewart D, Lindblad K, Zhang X, Patel JK, Kobashigawa J, Kransdorf EP. (2022) HLA Homozygosity and Sensitization in Kidney Transplant Candidates. Transplantation Direct 8, e1312.

Yu N, Askar M, Wadsworth K, Gragert L, Fernandez-Vina M. (2022) Current HLA Testing recommendations to support HCT. Human Immunology DOI: 10.1016/j.humimm.2022.04.008 PMID: 35798627

Ashman K, Zhuge H, Shanley E, Fox S, Halat S, Sholl A, Summa B, Brown JQ. Whole slide image data utilization informed by digital diagnosis patterns. J Pathol Inform. 2022 Jun 30;13:100113. doi: 10.1016/j.jpi.2022.100113. PMID: 36268057; PMCID: PMC9577055.

Lennerz JK, Pantanowitz L, Amin MB, Eltoum IE, Hameed MR, Kalof AN, Khanafshar E, Kunju LP, Lazenby AJ, Montone KT, Otis CN, Reid MD, Staats PN, Whitney-Miller CL, Abendroth CS, Aron M, Birdsong GG, Bleiweiss IJ, Bronner MP, Chapman J, Cipriani NA, de la Roza G, Esposito MJ, Fadare O, Ferrer K, Fletcher CD, Frishberg DP, Garcia FU, Geldenhuys L, Gill RM, Gui D, Halat S, Hameed O, Hornick JL, Huber AR, Jain D, Jhala N, Jorda M, Jorns JM, Kaplan J, Khalifa MA, Khan A, Kim GE, Lee EY, LiVolsi VA, Longacre T, Magi-Galluzzi C, McCall SJ, McPhaul L, Mehta V, Merzianu M, Miller SB, Molberg KH, Moreira AL, Naini BV, Nosé V, O'Toole K, Picken M, Prieto VG, Pullman JM, Quick CM, Reynolds JP, Rosenberg AE, Schnitt SJ, Schwartz MR, Sekosan M, Smith MT, Sohani A, Stowman A, Vanguri VK, Wang B, Watts JC, Wei S, Whitney K, Younes M, Zee S, Bracamonte ER. Ensuring remote diagnostics for pathologists: an open letter to the US Congress. Nat Med. 2022 Oct 20. doi: 10.1038/s41591-022-02040-6. Epub ahead of print. PMID: 36266514.

Sweeney PL, Jang A, Halat SK, Pal SK, Barata PC. Advanced papillary renal cell carcinoma: Epidemiology, genomic drivers, current therapies, and ongoing trials. Cancer Treat Res Commun. 2022 Sep 22;33:100639. doi: 10.1016/j.ctarc.2022.100639. Epub ahead of print. PMID: 36162322.

Utility of secretagogin as a marker for the diagnosis of lung neuroendocrine carcinoma. Baykara Y, Xiao Y, Yang D, Yakirevich E, Maleki S, Garcia-Moliner M, Wang LJ, Huang CK, Lu S. Virchows Arch. 2022 Jul;481(1):31-39. doi: 10.1007/s00428-022-03312-9. Epub 2022 Mar 31. PMID: 35357570

Wan Y, Slevin E, Koyama S, Huang CK, Shetty AK, Li X, Harrison K, Li T, Zhou B, Lorenzo SR, Zhang Y, Salinas JM, Xu W, Klaunig JE, Wu C, Tsukamoto H, Meng F. miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol induced liver injury. Hepatology Communication (In Press).

Hartono, A.B., Kang, H.J., Shi, L., Phipps, W. Ungerleider, N., Giardina, A., Chen, W., Spraggon, L. Somwar, R., Moroz, K., Drewry, D.H., Burow, M.E., Flemington, E., Ladanyi, M. and Lee, S.B. Salt-inducible kinase 1 is a potential therapeutic target in Desmoplastic small round cell tumor. 2022) Oncogenesis, 11, 18: PMID: 35443736.

Nguyen, K, Tran, MN, Rivera, A, Cheng, T, Windsor, GO, Chabot, AB, Cavanaugh, JE, Collins-Burow, BM, Lee, SB, Drewry, DH, Flaherty, PT. and Burow, ME. MAP3K family review and correlations with patient survival outcomes in various cancer types. 2022 Frontiers in Bioscience, 27:167. PMID 35638434.

Zhu G, Chen W, Tang CY, McVicar A, Edwards D, Wang J, McConnell M, Yang S, Li Y, Chang Z, Li YP. Knockout and Double Knockout of Ctsk and Mmp9 reveals a novel function of Ctsk as a regulator of gene expression in osteoclasts and bone homeostasis. Int J Biol Sci. 2022;18(14):5522-5538. PubMed PMID: 36147479; PubMed Central PMCID: PMC9461675 IF: 10.750

Vittori C, Jeansonne D, Yousefi H, Faia C, Lin Z, Reiss K, Peruzzi F. Mechanisms of miR-3189-3p-mediated inhibition of c-MYC translation in triple negative breast cancer. Cancer Cell Int. 2022 May 31;22(1):204.

Chen J, Barrett L, Lin Z, Kendrick S, Mu S, Dai L, Qin Z. Identification of natural compounds tubercidin and lycorine HCl against small-cell lung cancer and BCAT1 as a therapeutic target. J Cell Mol Med. 2022 May;26(9):2557-2565.

Toraih EA, Fawzy MS, Ning B, Zerfaoui M, Errami Y, Ruiz EM, Hussein MH, Haidari M, Bratton M, Tortelote GG, Hilliard S, Nilubol N, Russell JO, Shama MA, El-Dahr SS, Moroz K, Hu T, Kandil E. A miRNA-Based Prognostic Model to Trace Thyroid Cancer Recurrence. Cancers (Basel). 2022 Aug 26;14(17):4128. doi: 10.3390/cancers14174128. PMID: 36077665

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME. In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types. Clin Transl Oncol. 2022 Jan;24(1):127-144. doi: 10.1007/s12094-021-02677-8. PMID: 34370182

O’Grady T , Njock MS, Lion M, Bruyr J, Mariavelle E, Galvan B, Boeckx A, Struman I andDequiedt F. 2022. Sorting and packaging of RNA into extracellular vesicles shape Intracellular transcript levels. BMC Biology 20:72.

Njock MS*, O’Grady T*, Nivelles O, Lion M, Jacques S, Cambier M, Herkenne S, Muller F, Christian A, Remacle C, Guiot J, Rahmouni S, Dequiedt F and Struman I. 2022. Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming. Journal of Extracellular Vesicles. 11:e12228. *co-first authors

Pi L , Sun C, Jn-Simon N, Basha S, Thomas H, Figueroa V, Zarrinpar A, Cao Q, Petersen BE. CCN2/CTGF Promotes Liver Fibrosis Through Crosstalk with the Slit2/Robo Signaling. Journal of Cell Communication and Signaling. ( https://doi.org/10.1007/s12079-022-00713-y ).

Zhou J, Sun C, Yang L, Wang J, Jn-Simon N, Zhou C, Bryant A, Cao Q, Li C, Petersen B, Pi L. Liver regeneration and ethanol detoxification: A new link in YAP regulation of ALDH1A1 during alcohol-related hepatocyte damage. The FASEB J. 2022 Apr;36(4):e22224. doi: 10.1096/fj.202101686R. PMID: 35218575.

Li S, Sun X, Chen H, Liang J, Sun X, Chen M, Pi L, Ying Z, Ren B, Zhang L, Cao Q. Deletion of Interleukin 1 Receptor-Associated Kinase 1 Improves TLR4/STAT1/PPARγ-Cd36 Signaling-Mediated Alcoholic Fatty Liver. Advanced Research in Gastroenterology & Hepatology. 2022 January; 18(2):1-9. doi: 10.19080/ARGH.2021.18.555983.

IftikharR, PenroseH, King K, Kim Y, Rouiz, E, Kandil E, Machado H, Savkovic SD.FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis. 2022 Metabolites. DOI: 10.3390/metabo12030250

Safa F, Rasmussen T, Lobelle-Rich P, Collier S, Milligan N, Schmeig J, Collier S, Milligan N, Schmid J, Wiewiorowski C, Totaro D, Brown TC, Satyavarapu I, Badoo M, Ungerleider N, Flemington, Safah H, Saba N. Establishment and characterization of a new mantle cell lymphoma cell line with a NOTCH2 mutation, Arbo. eJHaem. 2022;14. https://doi.org/10.1002/jha2.580

Tian D , Lin Z, Kriner EM, Esneault DJ, Tran J, DeVoto JC, Okami N, Greenberg R, Yanofsky S, Ratnayaka S, Tran N, Livaccari M, Lampp M, Wang N, Tim S, Norton P, Scott J, Hu TY, Garry R, Hamm L, Delafontaine P,Yin XM. Authors' Reply. J Mol Diagn. 2022 Jan;24(1):103.

Di T , Lin Z, Kriner E, Esneault D, Tran J, Devoto N, Okami R, Greenberg S, Yanofsky S. Ratnayaka S, Tran N, Livaccari M, Lampp M, Wang N, Tim S, Norton P, Scott J, Hu TY, Garry R, Hamm L, Delafontaine P, Yin XM. Ct values of SARS-Cov2 assay does not predict viral transmissibility in college students. J. Molecular Diagnostics. 23(9): 1079-1084, 2021. Authors’ Reply: 24(1): 103, 2022.

Ning B, Youngquist BM, Li DD, Lyon CJ, Zelanzny A, Maness NJ, Tian D, Hu TY. Rapid detection of multiple SARS-CoV-2 variants of concern by PAM-targeting mutations. Cell Rep Methods, 2022 Feb 28;2(2):100173. doi: 10.1016/j.crmeth.2022.100173. Epub 2022 Feb 7.

Ashkan Shahbandi, Fang-Yen Chiu, Nathan A. Ungerleider, Raegan Kvadas, Zeinab Mheidly, Meijuan J. S. Sun, Di Tian, Daniel A. Waizman, Ashlyn Y. Anderson, Heather L. Machado, Zachary F. Pursell, Sonia G. Rao & James G. Jackson. Breast cancer cells survive chemotherapy by activating targetable

Ge D, O’Brien MJ, Savoie FH, Gimble JM, Qu Z Gilbert M, Clark-Patterson GL, Schuster JD, Miller KS, Wang A, Myers L, Zongbing Y. Human adipose-derived stromal/stem cells expressing doublecortin improve cartilage repair in rabbits and monkeys. NPJ Regen Med. 2021 Nov 30;6(1):82

Rao Z, Wang A, Liu W, Yin H, Li J, Tang LSL, Wu W, Shi W. Mammary Paget Disease With Melanocytic Proliferation Mimicking Malignant Melanoma in situ. Front Med (Lausanne). 2022 Mar 21;9:839954.

Ma W and Wu T. METTL3-Mediated m6A Modification Links Liver Homeostasis and Pathology . Am J Pathol. 2022 Jan;192(1):18-20. PMID: 34774849

Ma W and Wu T. RNA m6A modification in liver biology and its implication in hepatic diseases and carcinogenesis. Am J Physiol Cell Physiol. 2022 Oct 1;323(4):C1190-C1205. PMID: 36036444

Zhang J , Chen W, Ma W, Song K, Lee SB, Han C, Wu T. Epigenetic Silencing of 15-Hydroxyprostaglandin Dehydrogenase by Histone Methyltransferase EHMT2/G9a in Cholangiocarcinoma.Mol Cancer Res. 2022, 20(3):350-360. PMID: 34880125

Yan, S. (2022). "Role of TFEB in Autophagy and the Pathogenesis of Liver Diseases." Biomolecules 12(5): 672.

Yan S , Zhou J, Zhang H, Lin Z, Khambu B, Liu G, Ma M, Chen X, Chalasani N, Yin XM. Promotion of Diet-induced Obesity and Metabolic Syndromes by BID is Associated with Gut Microbiota. Hepatol Commun. 6(12):3349-3362. 2022

Huda, N., B. Khambu, G. Liu, H. Nakatsumi,S. Yan, X. Chen, M. Ma, Z. Dong, K. I. Nakayama and X.-M. Yin (2022). "Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver." Cell Mol Gastroenterol Hepatol 14(2): 333-355.

Long, J. X. Luo, D. Fang, H. Song, W. Fang, H. Shan, P. Liu, B. Lu, X-M. Yin*, L. Hong*, M. Li *. Discovery of an autophagy inducer J3 to lower mutant huntingtin and alleviate Huntington’s disease-related phenotype. Cell & Bioscience. 12:167, 2022. Doi.org/10.1186/s13578-022-00906-3 (*: co-corresponding authors).

Saxena, R. M. Nassiri, X.-M. Yin, and N. Morral. Insights from a high-fat diet fed mouse model with a humanized liver. Plos One, 17 (5): e0268260, 2022. PMID: 35533183

Livingston, M.J., S. Shu, Y. Fan, Z. Li, Q. Jiao, X.-M. Yin, M. Venkatachalam and Z. Dong. Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis. Autophagy, Published on line, 2022 May 1. doi: 10.1080/15548627.2022.2072054, PMID: 35491858

Liu, G., and X.-M. Yin. The role of extracellular vesicles in liver pathogenesis. Amer. J. Path 192: 1358-1367, 2022. PMID: 35752228.

2021

Elizaveta Belyaeva, M.D.

A Case Report with Severe Thrombocytopenia Induced by Axitinib. Koksal UI, Goffin J, Lewis B, Sartor OA, Belyaeva E, Socola F, Barata PC. Case Rep Hematol. 2020 Feb 7;2020:7520783. doi: 10.1155/2020/7520783. eCollection 2020.PMID: 32089908

SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro. Liu F, Han K, Blair R, Kenst K, Qin Z, Upcin B, Wörsdörfer P, Midkiff CC, Mudd J, Belyaeva E, Milligan NS, Rorison TD, Wagner N, Bodem J, Dölken L, Aktas BH, Vander Heide RS, Yin XM, Kolls JK, Roy CJ, Rappaport J, Ergün S, Qin X. Front Cell Infect Microbiol. 2021 Jul 6;11:701278. doi: 10.3389/fcimb.2021.701278. eCollection 2021.PMID: 34307198

Wei Chen and Yi-Ping Li, PhD

Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways. Tang CY, Wu M, Zhao D, Edwards D, McVicar A, Luo Y, Zhu G, Wang Y, Zhou HD, Chen W, Li YP. PLoS Genet. 2021 Jan 21;17(1):e1009233. doi: 10.1371/journal.pgen.1009233.

Ryan Craig, MD, PhD

Ibrahim M, Chen R, Vegel A, Panse K, Bhyravabhotla K, Harris K, Craig R, Safah H, Saba NS, Socola F. Treatment of myeloid sarcoma without bone marrow involvement with gemtuzumab ozogamicin-containing regimen. Leuk Res. 2021 Jul;106:106583. doi: 10.1016/j.leukres.2021.106583. Epub 2021 Apr 22. PMID: 33906021

Srikanta Dash, Ph.D.

Daniel J Klionsky et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4^th edition). Autophagy, 2021: PMID;33634751.

Dong Lin, Venu Reddy, Hanadi Osman, Adriana Lopez, Sadeq Radhi, Srikanta Dash and Yucel Aydin. Additional inhibition of Wnt/b-catenin signaling by Metformin in DAA treatments as a novel therapeutic strategy for HCV-infected patients. Cells, 2021;10:

Yucel Aydin, Ali R Koksal, Venu Reddy, Dong Lin, Hanadi Osman, Zahra Heidari, Sadeq R Rhadhi, William C Wimley, Mansour Parsi, and Srikanta Dash. Extracellular vesicle release promotes viral replication during persistent HCV infection. Cells, 2021; 10 (5):984.

Yucel Aydin, Ali R, Lin Dong, John W. Scott, Paul Thevenot, Arie Cohenand Srikanta Dash. Experimental validation of novel glypican 3 exosomes for the detection of hepatocellular carcinoma in liver cirrhosis. J Hepatocellular Carcinoma, 2021;8:1579-1596.

Srikanta Dash, Ali Riza Koksal, Lin Dong. Editorial Commentary: Fibrogenic signals persist in DAA-treated HCV patients after sustained virological response. Extracellular RNA, 2021

Loren Gragert, Ph.D.

Schindler E, Dribus M, Duffy BF, Hock K, Farnsworth CW, Gragert L, Liu C. (2021) Human leukocyte antigen genetic polymorphism in patients with Coronavirus Disease 2019 in Midwestern United States. HLA 98(4): 370-379.

Copley H, Gragert L, Leach A, Kosmoliaptsis, V. (2021) Influence of HLA class II polymorphism on predicted cellular immunity against SARS-CoV-2 at the population and individual level. Frontiers in Immunology 12:6-8.

Israeli S, Gragert L, Maiers M, Louzoun Y. (2021) HLA Haplotype Frequency Estimation for Heterogeneous Populations Using a Graph-Based Imputation Algorithm. Human Immunology 82(10) 746-757.

Sajulga R, Madbouly A, Fingerson S, Gragert L, Bashyal P, Bolon YT, Maiers M. (2021) Predicting HLA-DPB1 Permissive Probabilities through a DPB1 Prediction Service towards the Optimization of HCT Donor Selection. Human Immunology 82(21) 903-911.

Mayor N, Wang T, Lee SJ, Kuxhausen M, Vierra-Green C, Barker DJ, Auletta J, Bhatt VR, Gadalla SM, Gragert L, Inamoto Y, Morris GP, Paczesny S, Reshef R, Ringden O, Shaw BE, Shaw P, Spellman S, Marsh SGE. (2021) Impact of Previously Unrecognized HLA Mismatches Using Ultrahigh Resolution Typing in Unrelated Donor Hematopoietic Cell Transplantation. Journal of Clinical Oncology 39:21 2397-2409.

Story, MS, Wang T, Bhatt VR, Battiwalla M, Badawy SM, Kamoun M, Gragert L, Brown V, Baxter-Lowe LA, Marsh SGE, Gadalla SM, Schetelig J, Mytilineos J, Miklos D, Waller E, Kuxhausen M, Spellman S, Lee S, Armistead PM (2021) Genetics of HLA peptide presentation, and impact on outcomes in HLA-matched allo-HCT. Transplantation and Cellular Therapy 27:7 591-599.

Kransdorf E, Pando M, Stewart D, Lindblad K, Patel J, Kim I, Zhang X, Maiers M, Kobashigawa J, Gragert L. (2021) Stem Cell Donor HLA Typing Improves CPRA in Kidney Allocation. American Journal of Transplantation 21(1) 138-147.

Erik Flemington, PhD

Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity. Iftikhar R, Penrose HM, King AN, Samudre JS, Collins ME, Hartono AB, Lee SB, Lau F, Baddoo M, Flemington EF, Crawford SE, Savkovic SD. Oncogenesis. 2021 Nov 29;10(11):82. doi: 10.1038/s41389-021-00373-4.PMID: 34845203

SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity. Kim JH, Jeong K, Li J, Murphy JM, Vukadin L, Stone JK, Richard A, Tran J, Gillespie GY, Flemington EK, Sobol RW, Lim SS, Ahn EE. Nat Commun. 2021 Sep 21;12(1):5551. doi: 10.1038/s41467-021-25892-x.PMID: 34548489

EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape. Ungerleider N, Bullard W, Kara M, Wang X, Roberts C, Renne R, Tibbetts S, Flemington EK. PLoS Pathog 2021 May 6;17(5):e1009217. doi: 10.1371/journal.ppat.1009217. eCollection 2021 May.PMID: 33956915

Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy. Penrose HM, Iftikhar R, Collins ME, Toraih E, Ruiz E, Ungerleider N, Nakhoul H, Flemington EF, Kandil E, Shah SB, Savkovic SD. Sci Rep. 2021 Apr 27;11(1):9010. doi: 10.1038/s41598-021-88489-w.PMID: 33907256

Transcriptome analysis reveals sexual disparities in gene expression in rat brain microvessels. Chandra PK, Cikic S, Baddoo MC, Rutkai I, Guidry JJ, Flemington EK, Katakam PV, Busija DW. J Cereb Blood Flow Metab. 2021 Sep;41(9):2311-2328. doi: 10.1177/0271678X21999553. Epub 2021 Mar 9.PMID: 33715494

Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy. Ma T, Bai S, Qi Y, Zhan Y, Ungerleider N, Zhang DY, Neklesa T, Corey E, Dehm SM, Zhang K, *Flemington EK, *Dong Y. Cancer Lett. 2021 Apr 28;504:37-48. doi: 10.1016/j.canlet.2020.12.037. Epub 2021 Feb 6.PMID: 33556543

Data of relative mRNA and protein abundances of androgen receptor splice variants in castration-resistant prostate cancer. Ma T, Ungerleider N, Zhang DY, Corey E, *Flemington EK, *Dong Y. Data Brief. 2021 Jan 18;34:106774. doi: 10.1016/j.dib.2021.106774. eCollection 2021 Feb.PMID: 33537376

Transcriptional signatures of Zika virus infection in astrocytes. Schouest B, Peterson TA, Szeltner DM, Scheef EA, Baddoo M, Ungerleider N, Flemington EK, MacLean AG, Maness NJ. J Neurovirol. 2021 Feb;27(1):116-125. doi: 10.1007/s13365-020-00931-3. Epub 2021 Jan 6.PMID: 33405202

SON inhibits megakaryocytic differentiation via repressing RUNX1 and the megakaryocytic gene expression program in acute megakaryoblastic leukemia. Vukadin L, Kim JH, Park EY, Stone JK, Ungerleider N, Baddoo MC, Kong HK, Richard A, Tran J, Giannini H, Flemington EK, Lim SS, Ahn EE. Cancer Gene Ther. 2021 Sep;28(9):1000-1015. doi: 10.1038/s41417-020-00262-9. Epub 2020 Nov 27.PMID: 33247227

Bilon Khambu, PhD

Klionsky, D.J. …… B. Khambu, ….. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4^th edition). Autophagy 2021 Feb 8;1-382. doi: 10.1080/15548627.2020.1797280. Online ahead of print.

Yan, S. B. Khambu, X. Chen, Z. Dong, G. Guo, and X.-M. Yin. Hepatic autophagy deficiency remodels gut microbiota for adaptive protection via FGF15-FGFR4 signaling. Cellular and Molecular Gastroenterology and Hepatology. 11: 973-997,2021. https://doi.org/10.1016/j.jcmgh.2020.10.011. PMID: 33127558

Zhen Lin, PhD

Nanbo A, Furuyama W, Lin Z. RNA Virus-Encoded miRNAs: Current Insights and Future Challenges. Frontiers in Microbiology. 2021;12:679210. Published 2021 Jun 24. doi:10.3389/fmicb.2021.679210

Tian D, Lin Z, Kriner EM, Esneault DJ, Tran J, DeVoto JC, Okami N, Greenberg R, Yanofsky S, Ratnayaka S, Tran N, Livaccari M, Lampp M, Wang N, Tim S, Norton P, Scott J, Hu TY, Garry R, Hamm L, Delafontaine P, Yin XM. Ct Values Do not Predict SARS-CoV-2 Transmissibility in College Students. J Mol Diagn. 2021 Jun 5:S1525-1578(21)00163-X. doi: 10.1016/j.jmoldx.2021.05.012.

Becnel D, Abdelghani R, Nanbo A, Avilala J, Kahn J, Li L, Lin Z. Pathogenic Role of Epstein-Barr Virus in Lung Cancers. Viruses. 2021 May. 13(5), 877

Avilala J, Becnel D, Abdelghani R, Nanbo A, Kahn J, Li L, Lin Z. Role of virally encoded circular RNAs in the pathogenicity of human oncogenic viruses. Frontiers in Microbiology. 2021 April. 12:657036.

Del Valle L, Dai L, Lin HY, Lin Z, Chen J, Post SR, Qin Z. Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression. J Cell Mol Med. 2021 Feb 4. doi: 10.1111/jcmm.16307.

Ning B, Yu T, Zhang S, Huang Z, Tian D, Lin Z, Niu A, Golden N, Hensley K, Threeton B, Lyon CJ, Yin XM, Roy CJ, Saba NS, Rappaport J, Wei Q, Hu TY. A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Science Advances. 2021 Jan 8; 7(2):eabe3703. doi: 10.1126/sciadv.abe3703.

Sean Lee, Ph.D.

Ogura, K., Somwar, R., Hmeljak, J., Benayed, R., Boroujeni, A.M., Jungbluth, A., Magnan, H., Mattar, M.S., Khodos, I., Asher, M., Hartono, A.B., La Quaglia, M.P., de Stanchina, E., Pratilas, C., Lee, S.B., Spraggon, L. and Ladanyi, M. (2021) Therapeutic potential of NTRK3 inhibition in Desmoplastic Small Round Cell Tumor. Clinical Cancer Research 27:1184-1194. PMID: 33229458.

Matossian, M., Elliott, S., Van T. Hoang, Burks, H.E., Wright, M.K., Alzoubi, M., Yan, T., Chang, T., Wathieu, H., Windsor, G., Hartono, A.B., Lee, S.B., Zuercher, W.J., Drewry, D.H., Wells, C., Kapadia, N., Buechlein, A., Fang, F., Nephew, K.P., Collins-Burow, B.M. and Burow M.E. (2021) NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells. Breast Cancer Research and Treatment, 189:49-61. PMID: 33749548.

Iftikhar, R., Penrose, H.M., King, A.N., Samudre, J.S., Collins, M.E., Hartono, A.B., Lee, S.B., Lau, F., Badoo, M., Flemington, E.F., Crawford, S.E. and Savkovic, S.D. (2021) Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity. Oncogenesis, Nov 29;10(11):82. PMID: 34845203.

Smith, R.S., Odintsov, I., Liu, Z., Lui, A.J-W., Hayashi, T., Vojnic, M., Suehara, Y., Delasos, L., Mattar, M.S., Hmeljak, J., Ramirez, H.A., Shaw, M., Bui, G., Gladstone, E., Kunte, S., Magnan, H., Khodos, I., de Stanchina, E., La Quaglia, M.P., Yao, J., Lae, M., Lee, S.B., Spraggon, L., Pratilas, C.A., Ladanyi, M. and Somwar, R. (2021) Novel patient-derived models of DSRCT enable validation of ERBB signaling as a potential therapeutic vulnerability. Disease Models & Mechanisms, online ahead of print, PMID: 34841430.

Zhang, J., Chen, W., Ma, W., Song, K., Lee, S.B., Han, C. and Wu. T. Epigenetic silencing of 15-hydroxyprostaglandin dehydrogenase by histone methyltransferase EHMT2/G9a in cholangiocarcinoma. (2021) Molecular Cancer Research, Accepted, in print.

Krzysztof Moroz, M.D.

Toraih EA, Fawzy MS, Hussein MH, El-Labban MM, Ruiz EML, Attia AA, Halat S, Moroz K, Errami Y, Zerfaoui M, Kandil E. MicroRNA-Based Risk Score for Predicting Tumor Progression Following Radioactive Iodine Ablation in Well-Differentiated Thyroid Cancer Patients: A Propensity-Score Matched Analysis. Cancers (Basel). 2021 Sep 16;13(18):4649. doi: 10.3390/cancers13184649. PMID: 34572876

Aydin Y, Chedid M, Chava S, Danielle Williams D, Liu S, Hagedorn CH, Sumitran-Holgersson S, Reiss K, Moroz K, Lu H, Balart LA, Dash S. Retraction Note: Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture. Sci Rep. 2021 Sep 1;11(1):17779. doi: 10.1038/s41598-021-97265-9. PMID: 34471176

Matossian MD, Chang T, Wright MK, Burks HE, Elliott S, Sabol RA, Wathieu H, Windsor GO, Alzoubi MS, King CT, Bursavich JB, Ham AM, Savoie JJ, Nguyen K, Baddoo M, Flemington E, Sirenko O, Cromwell EF, Hebert KL, Lau F, Izadpanah R, Brown H, Sinha S, Zabaleta J, Riker AI, Moroz K, Miele L, Zea AH, Ochoa A, Bunnell BA, Collins-Burow BM, Martin EC, Burow ME. In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types. Clin Transl Oncol. 2021 Aug 9. doi: 10.1007/s12094-021-02677-8. Online ahead of print. PMID: 34370182

Liya Pi, PhD

Chen M, Sun X, Wei W, Cucarella C, Martín-Sanz P, Casado M, Pi L, Ren B, Cao Q. Hepatic COX-2 expression protects mice from an alcohol-high fat diet-induced metabolic disorder by involving protein acetylation related energy metabolism. Alcohol. 2021 92:41-52.

RRY Inhibits Amyloid-β_1-42 Peptide Aggregation and Neurotoxicity. Sun X, Duan S, Cao A, Villagomez B, Lin R, Chen H, Pi L, Ren B, Chen R, Chen M, Ying Z, Fang S, Cao Q. J Alzheimers Dis Rep. 2021 Jun 8;5(1):479-495. doi: 10.3233/ADR-210012. eCollection 2021.PMID:34368633

Suzana Savkovic, PhD

Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity. Iftikhar R, Penrose H, King K, Samudre J, Collins M, , Hartono A, Lee S, Lau F, Baddoo M, Flemington E, Crawford S, Savkovic SD., 2021 Oncogenesis. doi.org/10.1038/s41389-021-00373-4. *Blog for Nature community

Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy. Penrose H, Iftikhar R, Collins M, Toraih E, Ruiz E, Ungerleider N, Nakhoul H, Flemington E, Kandil E, Shah S, Savkovic SD. Scientific Report. 2021; 11: 9010. doi: 10.1038/s41598-021-88489-wPMC8079702

Janet Schmid, M.D.

Xie J, Jang A, Vegel A, Hajja Y, Mouawad Y, Baghian A, Berbari B, Schmid J, Socola F, Safah H, Saba N. Successful treatment of “accelerated” chronic lymphocytic leukemia with single agent ibrutinib: A report of two cases.” Leukemia Research Reports, May 2021(https://doi.org/10.1016/.lrr.2021.100247) 2213-0489/c2021

J Xie, A Jang, M. Uemura, S. Nakazawa, T. Calimeri, A. JM Ferreri, S. R. Chen, J. L. Schmid, T. C. Brown, F. Socola, H. Safah, N. S. Saba. Systemic vs Intrathecal Central Nervous System Prophylaxis in Primary Adrenal/Renal Diffuse Large B-cell lymphoma: A Multi-institution Retrospective Analysis and Systematic Review. Leukemia Research Reports. Aug 3, 2021.

(https://doi.org/10.1016/j.lrr.2021.100263)

John Scott, M.D., Ph.D.

Yucel Aydin, Ali Riza Koksal, Paul Thevenot, Srinivas Chava1 Zahra Heidari, Dong Lin1 Tyler Sandow, Krzysztof Moroz, Mansour A Parsi, John Scott, Ari Cohen, Srikanta Dash: Experimental Validation of Novel Glypican 3 Exosomes for the Detection of Hepatocellular Carcinoma in Liver Cirrhosis: Journal of Hepatocellular Carcinoma 2021:8 1579–1596

Bo Ning, Zhen Huang, Brady M. Youngquist, John W Scott, Alex Niu, Christine M. Bojanowski, Kevin J. Zwezdaryk, Nakhle S. Saba, Jin Fan, Xiao-Ming Yin, Jing Cao, Christopher J. Lyon, Chen-zhong Li, Chad J. Roy, and Tony Y. Hu: Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma" Nature Nanotechnology: doi.org/10.1038/s41565-21-00939-8

DiTian, Zhen Lin, Ellie M. Kriner, Dalton J. Esneault, Jonathan Tran, Julia C. DeVoto, Naima Okami, Rachel Greenberg, Sarah Yanofsky, Swarnamala Ratnayaka, Nicholas Tran, Maeghan Livaccari, Marla Lampp, Noel Wang, Scott Tim, Patrick Norton, JohnScott, Y.Hu, Robert Garry, Patrice Delafontaine, Lee Hamm, Xiao-MingYin: SARS-CoV-2 Load does not Predict Transmissibility in College Students, https://doi.org/10.1101/2021.03.02.21252105

Zhen Huang,^1,2,3 Bo Ning,^1,3 He S. Yang,⁴ Brady M. Youngquist,^1,3 Alex Niu,⁵ Christopher J. Lyon,^1,3 Brandon J. Beddingfield,⁶ Alyssa C. Fears,⁶ Chandler H. Monk,⁷ Amelie E. Murrell,⁷ Samantha J. Bilton,⁷ Joshua P. Linhuber,⁷ Elizabeth B. Norton,⁷ Monika L. Dietrich,⁸ Jim Yee,⁴ Weihua Lai,²John W. Scott,⁹Xiao-Ming Yin,⁹ Jay Rappaport,^7,10 James E. Robinson,⁸ Nakhle S. Saba,⁵ Chad J. Roy,^6,7 Kevin J. Zwezdaryk,⁷ Zhen Zhao,⁴ and Tony Y. Hu^1,3 Sensitive tracking of viral RNA in plasma through all stages of SARS-CoV-2 infection. J Clin Invest 2021;131(7) e146031

Di Tian, M.D., Ph.D.

Ning B, Yu T, Zhang S, Huang Z, Tian D, Lin Z, Niu A, Golden N, Hensley K, Threeton B, Lyon CJ, Yin XM, Roy CJ, Saba NS, Rappaport J, Wei Q, Hu TY. A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Sci Adv. 2020 Dec 11:eabe3703. doi: 10.1126/sciadv.abe3703. 2021.

Tian D, Lin Z, Kriner EM, Esneault DJ, Tran J, DeVoto JC, Okami N, Greenberg R, Yanofsky S, Ratnayaka S, Tran N, Livaccari M, Lampp M, Wang N, Tim S, Norton P, Scott J, Hu TY, Garry R, Hamm L, Delafontaine P, Yin XM. Ct Values Do not Predict SARS-CoV-2 Transmissibility in College Students. J Molecular Diagnosis. Jun 5;S1525-1578(21)00163-X. doi: 10.1016/j. jmoldx.2021.05.012. 2021

Arnaud C. Drouin, Marc Theberge, Sharon Liu, Allison Smither, Shelby Flaherty, Mark Zeller, Gregory P. Geba, Peter Reynaud, W. Benjamin Rothwell, Alfred P. Luk, Di Tian, Matthew L. Boisen, Luis M. Branco, Kristian G. Andersen, James E. Robinson, Robert F. Garry, Dahlene N. Fusco. Successful Clearance of 300 Day SARS-CoV-2 Infection in a Subject with B-Cell Depletion Associated Prolonged (B-DEAP) COVID by REGEN-COV Anti-Spike Monoclonal Antibody Cocktail. Viruses. 13(7): 1202 doi: 10.3390/v13071202. 2021.

Snarski P, Sukhanov S, Yoshida T, Higashi Y, Danchuk S, Chandrasekar B, Tian D, Rivera-Lopez V, Delafontaine P. Macrophage-Specific IGF-1 Overexpression Reduces CXCL12 Chemokine Levels and Suppresses Atherosclerotic Burden in Apoe-Deficient Mice. Arterioscler Thromb Vasc Biol. ATVBAHA121316090. doi: 10.1161/ATVBAHA.121.316090. 2021.

Tong Wu, M.D., Ph.D.

Ma W and Wu T. METTL3-Mediated m6A Modification Links Liver Homeostasis and Pathology. Am J Pathol 2021 Nov 11;S0002-9440(21)00473-9. doi: 10.1016/j.ajpath.2021.10.015. PMID: 34774849

Zhang J*, Chen W, Ma W, Song K, Lee S, Han C, Wu T*. Epigenetic Silencing of 15-Hydroxyprostaglandin Dehydrogenase by Histone Methyltransferase EHMT2/G9a in Cholangiocarcinoma. Mol Cancer Res. 2021 Dec 8:molcanres.0536.2021. doi: 10.1158/1541-7786.MCR-21-0536. Epub ahead of print. PMID: 34880125. *corresponding authors.

Shengmin Yan, PhD

Yan, S, and X.-M. Yin. Gut microbiome in liver pathophysiology and cholestatic liver disease. Liver Research. Published online, Aug. 2021. https://doi.org/10.1016/j.livres.2021.08.001

Xiao-Ming Yin, M.D., Ph.D.

Wang, Y. J. Zhu, Z. Liu, S. Shu, Y. Fu, Y. Liu, J. Cai, C. Tang, Y. Liu, X. Yin, Z. Dong. The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury. Redox Biology. 38:101767, 2021,

Yan, S. B. Khambu, X. Chen, Z. Dong, G. Guo, and X.-M. Yin. Hepatic autophagy deficiency remodels gut microbiota for adaptive protection via FGF15-FGFR4 signaling. Cellular and Molecular Gastroenterology and Hepatology. 11: 973-997,2021.

Ning, B., T. Yu, S. Zhang, Z. Huang, D. Tian, Z. Lin, A. Niu, N. Golden, C. Lyon, A. Drouin, D. Fusco, X-M. Yin, N. Saba, J. Rapaport, Q. Wei and T. Hu. A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Science Advances. 8;7(2):eabe3703, 2021

Huang Z, Ning B, Yang HS, Youngquist BM, Niu A, Lyon CJ, Beddingfield BJ, Fears AC, Monk CH, Murrell AE, Bilton SJ, Linhuber JP, Norton EB, Dietrich ML, Yee JK, Lai W, Scott JW, Yin X-M, Rappaport J, Robinson JE, Saba NS, Roy CJ, Zwezdaryk KJ, Zhao Z, Hu TY, Sensitive tracking of circulating viral RNA through all stages of SARS-CoV-2 infection. J. Clin. Inv. 2021 Feb 9:146031.

Di, T, Z. Lin, E. Kriner, D. Esneault, J. Tran, J. Devoto, N. Okami, R. Greenberg, S. Yanofsky, S. Ratnayaka, N. Tran, M. Livaccari, M. Lampp, N. Wang, S. Tim, P. Norton, J. Scott, T. Y. HU, R. Garry, L. Hamm, P. Delafontaine, X-M. Yin. Ct values of SARS-Cov2 assay does not predict viral transmissibility in college students. J. Molecular Diagnostics. Accepted. May 27, 2021

Liu, F, K. Han, R. Blair, K. Kenst, Z. Qin, B. Upcin, P. Worsdorfer, C. C. Midkiff, J. Mudd, E. Belyaeva, N. S. Milligan, T. Dorison, N. Wagner, J. Bodem, L. Dolken, B. H. Aktas, R. Vander Heide, X.-M. Yin, J. K. Kolls, C. J. Roy, J. Rappaport, S. Ergun, and X. Qin. SARS-CoV-2 infects endothelial cells in vivo and in vitro. Front. Cell. Infect. Micriobiol. Published on line July 6, 2021. DOI: 10.3389/fcimb.2021.701278

Ning, B., Z. Huang, B. M. Youngquist, J. W. Scott, A. Niu, C. M. Bojanowski, K. J. Zwezdaryk, N. S. Saba, J. Fan, X.-M. Yin, J. Cao, C. J. Lyon, C-z. Li, C. J. Roy and T. Y. Hu. Liposome-mediated detection of SARS-CoV-2 RNA-positive extracellular vesicles in plasma, Nature Nanotechnology, Published. July 22, 2021.

Reagan-Steiner, S., J. Bhatnagar, R. B. Martines, N.S. Milligan, C. Gisondo, F.B. Williams, E. Lee, L. Estetter, H Bullock, C.S. Goldsmith, P. Fair, J. hand, G. Richardson, k.R. Woodworth, T. Oduyebo, R. R. Galang, R. Phillips, E. Belyaeva, X.-M. Yin, D. Meaney-Delman, T. M. Uyeki, D. J. Roberts, S. R. Zaki. Detection of SARS-CoV-2 in neonatal autopsy tissues and placenta: insights into vertical transmission. Emerging Infectious Diseases, Accepted, 2021

Klionsky, D.J. …… X.-M. Yin, ….. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4^th edition). Autophagy 2021 Feb 8;1-382. doi: 10.1080/15548627.2020.1797280. Online ahead of print.

Yan, S, and X.-M. Yin. Gut microbiome in liver pathophysiology and cholestatic liver disease. Liver Research. Published online, Aug. 2021. https://doi.org/10.1016/j.livres.2021.08.001

Lorene Yoxtheimer, M.D.

Gunning WT 3rd, Yoxtheimer L, Smith MR. Platelet Aggregation Assays Do Not Reliably Diagnose Platelet Delta Granule Storage Pool Deficiency. J Hematol. 2021;10(4):196-201. doi:10.14740/jh832

Jinqiang Zhang, Ph.D.

2020

Srikanta Dash, Yucel Aydin and Tong Wu. Invited Review: Integrated stress response in hepatitis C promotes Nrf2-mediated chaperone-mediated autophagy: a novel mechanism for host-microbe survival and HCC development in liver cirrhosis. Seminars in Cell and Developmental Biology, 2020;101:20-35.

Srikanta Dash, Yucel Aydin, Kyle E Widmer and Leela Nayak. Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the impact of Direct Acting Antiviral Treatment. Journal of Hepatocellular Carcinoma, 2020;7:1-32.

Sruti Chandra, Hoang Michael Nguyen,Kylar Wiltz, Nicholas Hall, Shanzay Chaudhry, George Olverson, Tarun Mandal, Srikanta Dash , Anup Kundu. Aptamer-functionalized Hybrid Nanoparticles to Enhance the Delivery of Doxorubicin into Breast Cancer Cells by Silencing P-glycoprotein. Journal of Cancer Treatment and Diagnosis, 2020;4(1):1-13.

Srikanta Dash and Yucel Aydin. Editorial: Innate immune control of HCV infection through the Jak-Stat signaling. Digestive Medicine Research, 2020 (in press).

Dong Lin, Venu Reddy, Hanadi Osman, Adriana Lopez, Sadeq Radhi, Srikanta Dash and Yucel Aydin. Metformin reverses b-catenin signaling caused by chronic HCV infection and HCV clearance by direct-acing antiviral agents. Scientific Report, 2020 (in press).

Nusrat Chowdhury, Shanzay Chowdhury, Nicholas Hall, George Olverson, Qian-Jin Zhang, Tarun Mandal, Srikanta Dash, Anup Kundu. Targeted delivery of doxorubicin liposome for Her-2 positive breast cancer treatment. American Association of Pharamceutical Scientist (AAPS PharmSciTech), 2020;21:202.

Huang Z, Tian D, Liu Y, Lin Z, Lyon CJ, Lai W, Fusco D, Drouin A, Yin, X, Hu T, Ning B. Ultra-sensitive and high-throughput CRISPR-p owered COVID-19 diagnosis. Biosensors & bioelectronics, 22 May 2020, 164:112316 PMID

Alger J, Cafferata ML, Alvarado T, Ciganda A, Corrales A, Desale H, Drouin A, Fusco D, Garcia J, Gibbons L, Harville E, Lopez W, Lorenzana I, Muñoz-Lara F, Palou E, Retes E, Sierra M, Stella C, Xiong X, Zambrano LI, Buekens P. Using prenatal blood samples to evaluate COVID-19 rapid serologic tests specificity to the Maternal and Child Health Journal (accepted for publication 7-09-2020). PMID

Alger J, Caferata ML, Alvarado T, Ciganda A, Corrales A, Desale H, Drouin A, Fusco D,Garcia J, Gibbons L, Harville E, Lopez W, Lorenzana I, Muñoz Lara F, Palou E, Retes E, Sierra M, Stella, C, Xiong X, Zambrano LI and Buekens P. Using Prenatal Blood Samples to Evaluate COVID 19 Rapid Serologic Tests Specificity. Maternal and Child Health Journal. 2020. 24, 1099-1103. doi: 10.1007/s10995-020-02981-9 PMID: 32671537

Yin Q, Strong MJ, Zhuang Y, Flemington EK, Kaminski N, de Andrade JA, Lasky JA. Assessment of viral RNA in idiopathic pulmonary fibrosis using RNA-seq. BMC Pulm Med. 2020 Apr 3;20(1):81. doi: 10.1186/s12890-020-1114-1. PMID: 32245461

Yadav S, Anbalagan M, Baddoo M, Chellamuthu VK, Mukhopadhyay S, Woods C, Jiang W, Moroz K, Flemington EK, Makridakis N. Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians. Oncogene. 2020 May;39(21):4299-4311. doi: 10.1038/s41388-020-1280-x. Epub 2020 Apr 16. PMID: 32300177

Zhang W, Dong Y, Sartor O, Flemington EK, Zhang K. SEER and Gene Expression Data Analysis Deciphers Racial Disparity Patterns in Prostate Cancer Mortality and the Public Health Implication. Sci Rep. 2020 Apr 22;10(1):6820. doi: 10.1038/s41598-020-63764-4. PMID: 32321981

Vukadin L, Kim JH, Park EY, Stone JK, Ungerleider N, Baddoo MC, Kong HK, Richard A, Tran J, Giannini H, Flemington EK, Lim SS, Ahn EE. SON inhibits megakaryocytic differentiation via repressing RUNX1 and the megakaryocytic gene expression program in acute megakaryoblastic leukemia. Cancer Gene Ther. 2020 Nov 27. doi: 10.1038/s41417-020-00262-9. Online ahead of print. PMID: 33247227

Schouest B, Peterson TA, Szeltner DM, Scheef EA, Baddoo M, Ungerleider N, Flemington EK, MacLean AG, Maness NJ. Transcriptional signatures of Zika virus infection in astrocytes. J Neurovirol. 2021 Jan 6. doi: 10.1007/s13365-020-00931-3. Online ahead of print. PMID: 33405202

Ungerleider, N, Bullard, W, Kara, M, Wang, X, Roberts, C, Renne, R, Tibbetts, S, Flemington, EK. EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape. bioRxiv 2020.12.21.423766; doi: https://doi.org/10.1101/2020.12.21.423766

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Kaur N, Pinelli D, Kransdorf E, Pando M, Smith G, Murphey C, Kamoun M, Bray R, Tambur A, Gragert L. (2020) A blueprint for electronic utilization of ambiguous molecular HLA typing data in organ allocation systems and virtual crossmatch. Human Immunology 81(2-3) 65-72.

Copley H, Gragert L, Leach A, Kosmoliaptsis, V. (2020) Influence of HLA class II polymorphism on predicted cellular immunity against SARS-CoV-2 at the population and individual level. bioRxiv https://doi.org/10.1101/2020.12.24.424326 Prepints.

Sabol RA, Bubenzer V, Moroz K, Halat S, Dang A, Ferdinand K, Traylor A, Boyd C, Harris K. Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease. Case Rep Ophthalmol Med. 2020 Sep 5;2020:8873078. doi: 10.1155/2020/8873078. PMID: 32963860; PMCID: PMC7492922.

Ma W, Han C, Zhang J, Song K, Chen W and Wu T. The histone methyltransferase G9a promotes cholangiocarcinogenesis through regulation of the Hippo pathway kinase LATS2 and YAP signaling pathway. Hepatology 2020. 72(4): 1283-1297. PMID: 31990985.

Zhang J, Han C, Song K, Chen W, Ungerleider N, Yao L, Ma W and Wu T. The long noncoding RNA MALAT1 regulates TGFbeta/Smad signaling through formation of a lncRNA-protein complex with Samds, SETD2 and PPM1A in hepatic cells. PloS One 2020, 15(1): e0228160. PMID: 31995604.

Song K, Kwon H, Han C, Chen W, Zhang J, Ma W, Dash S, Gandhi CR and Wu T. Yes- associated protein in Kupffer cells enhances the production of pro-inflammatory cytokines and promotes the development of Nonalcoholic steatohepatitis Hepatology 2020, 72(1):72-87. PMID: 31610032.

Ning B, Yu T, Zhang S, Huang Z, Tian D, Lin Z, Niu A, Golden N, Hensley K, Threeton B, Lyon CJ, Yin XM, Roy CJ, Saba NS, Rappaport J, Wei Q, Hu TY. A smartphone-read ultrasensitive and quantitative saliva test for COVID-19. Sci Adv. 2020 Dec 11:eabe3703. doi: 10.1126/sciadv.abe3703. (impact factor 13.116)

Chen J*, Goyal N*, Dai L*, Lin Z*, Del Valle L, Zabaleta J, Liu J, Post S, Foroozesh M, Qin Z. Developing new ceramide analogs and identifying novel sphingolipid controlled genes against a virus-associated lymphoma. Blood. 2020Nov:136(19):2175-2187. doi: 10.1182/blood.2020005569. (*Co-first author).

Zhao M, Nanbo A, Becnel D, Qin Z, Morris GF, Li L, Lin Z*. Ubiquitin Modification of the Epstein-Barr Virus Immediate Early Transactivator Zta. J Virol. 2020 Oct: JVI.01298-20. doi: 10.1128/JVI.01298-20. PMID: 32847852. (*Corresponding author)

Thompson JW Jr, Mikolajewski AJ, Kissinger P, McCrossen P, Smither A, Chamarthi GD, Lin Z, Tian D. An Epidemiologic Study of COVID-19 Patients in a State Psychiatric Hospital: High Penetrance With Early CDC Guidelines. Psychiatr Serv. 2020 Oct 6:appips202000270. doi: 10.1176/appi.ps.202000270. PMID: 33019856.

Huang Z, Tian D, Liu Y, Lin Z, Lyon CJ, Lai W, Fusco D, Drouin A, Yin X, Hu T, Ning B. Ultra-sensitive and high-throughput CRISPR-powered COVID-19 diagnosis. Biosens Bioelectron. 2020 Sep 15;164:112316. doi:10.1016/j.bios.2020.112316.

Chen J, Lin Z, Barrett L, Dai L, Qin Z. Identification of new therapeutic targets and natural compounds against diffuse intrinsic pontine glioma (DIPG). Bioorg Chem. 2020 Jun;99:103847. doi: 10.1016/j.bioorg.2020.103847.

Dai L*, Chen J*, Lin Z*, Wang Z, Mu S, Qin Z. Targeting Sphingosine Kinase by ABC294640 against Diffuse Intrinsic Pontine Glioma (DIPG). J Cancer. 2020 May 22;11(16):4683-4691. (*Co-first author).

Zhang Y, Nguyen A, Chun M, Lin Z, Ross J, Sun L. Ninety Days in: A comprehensive Review of the Ongoing COVID-19 Outbreak. Health Sci J. 2020; Vol.14. No. 2:706

Sabol RA, Bubenzer V, Moroz K, Halat S, Dang A, Ferdinand K, Traylor A, Boyd C, Harris K. Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease Case Rep Ophthalmol Med. 2020 Sep 5;2020:8873078. doi: 10.1155/2020/8873078. eCollection 2020. PMID: 32963860

Liu S, Liu F, Zhang B, Yan P, Rowan BG, Mageed AB, Steele C, Jazwinski SM, Moroz K, Wung A, Myers L, Sartor O, Zhang Q. CD4+ T helper 17 cell response of aged mice promotes prostate cancer cell migration and invasion. The Prostate, 01 May 2020, DOI: 10.1002/pros.23990

Yadav S, Anbalagan M, Baddoo M, Chellamuthu VK, Mukhopadhyay S, Woods C, Jiang W, Moroz K, Flemington EK, Makridakis N. Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians. Oncogene (2020) Apr 16. doi: 10.1038/s41388-020-1280-x. PMID: 32300177

Zhao, M., A. Nanbo, D. Becnel, Z. Qin, G.F. Morris, L. Li and Z. Lin (2020). "Ubiquitin Modification of the Epstein-Barr Virus Immediate Early Transactivator Zta." J Virol 94(22):e01298-20. doi: 10.1128/JVI.01298-20. Print 2020 Oct 27. PMID: 32847852.

Liu, Y. Z., C. A. Miller, Y. Zhuang, S. S. Mukhopadhyay, S. Saito, E. B. Overton and G.F. Morris (2020). "The Impact of the Deepwater Horizon Oil Spill upon Lung Health-Mouse Model-Based RNA-Seq Analyses." Int J Environ Res Public Health 17(15):5466. doi: 10.3390/ijerph17155466. PMID: 32751227.

Alex Niu, April McDougal, Bo Ning, Firas Safa, Alfred Luk, David M. Mushatt, Adeem Nachabe, Kevin J. Zwezdaryk, James Robinson, Tim Peterson, Francisco Socola, Hana Safah, Tony Hu, Nakhle S. Saba. COVID-19 in allogeneic stem cell transplant: high false-negative probability and role of CRISPR and convalescent plasma. Bone Marrow Transplantation 2354–2356(2020)

Pal, Priya; Ibrahim, Moayed; Niu, Alex; Zwezdaryk, Kevin J; Tatje, Elise; Robinson, William R; Ko, Leta; Satyavarapu, Ishwarya; Jones, Wallace E; Nachabe, Adeem; Luk, Alfred; Mushatt, David M; Halvorson, Karin; Denson, Joshua L; Smith, Charles C; Simeone, Francesco; Davis, Gaynelle; Gill, Sukhmani K; McDougal, April; Vigh, Aniko S; Peterson, Tim G; Ning, Bo; Hu, Tony; Socola, Francisco; Robinson, James; Safah, Hana; Saba, Nakhle S. Safety and efficacy of COVID-19 convalescent plasma in severe pulmonary disease: A report of 17 patients. Transfus Med ; 2020 Oct 19.3:

Savkovic SD. Gut microbes effects on host metabolic alterations in health and disease. Gut Microbes. 2020 May 3;11(3):249-252. doi: 10.1080/19490976.2020.1754097. PMID: 32543319

Ruiz, E, Penrose H, Heller S, Nakhoul H, Flemington E, Kandil E, Savkovic SD. Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease. Gut Microbes 2020 May 3: 11(3):350- 63. PMID:31063017 *Cover page image

Quinn ZL, Zakharia K, Schmid J, Schmieg J, Safah H, and Saba N. Primary dural diffuse large B-cell lymphoma: a comprehensive review of survival and treatment outcomes. Clinical Lymphoma, Myeloma and Leukemia, Volume 20, Issue 2, February 2020, Pages e105-e112.

Xie J, Jang A, Chen SR, Uemura M, Nakazawa S, Calimeri T, Ferreri AJM, Schmid JL, Brown T, Socola F, Safah H. Saba N. Recommendations for Central Nervous System Prophylaxis in Primary Adrenal/Renal Diffuse Large B-cell Lymphoma: A Multi-institution Retrospective Analysis and Literature Review.Submitted for publication, March 2020.

Xie J, Nachabe A, Hathaway LJ, Farah B, Berbari B, Li Y, Brown TC, Schmid J, Socola F, Saba NS, Safah H. The prognostic implications of tetraploidy/near-tetraploidy in acute myeloid leukemia: a case series and systematic review of the literature. Leukemia & Lymphoma, 62:1, 203-210. DOI 10.1080/10428194.2020.1817435. (https://doi.org/10.1080/10428194.2020.1817435.)

Huang Z, Tian D, Liu Y, Lin Z, Lyona C, Lai W, Fuscoe D, Drouine A, Yin X-M, Hua T, Ning B. Ultra-sensitive high throughput CRISPR diagnosis of COVID-19. Biosensors and Bioelectronics 164:112316, 2020

Ma W, Han C, Zhang J, Song K, Chen W, Kwon H, and Wu T. The Histone Methyltransferase G9a Promotes Cholangiocarcinogenesis through Regulation of the Hippo Pathway Kinase LATS2 and YAP Signaling Pathway. Hepatology. 2020 Jan 28. doi: 10.1002/hep.31141. [Epub ahead of print]. PMID:31990985

Zhang J, Han C, Song K, Chen W, Ungerleider N, Ma W, and Wu T. The long- noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells. PLOS ONE. 2020 Jan 29;15(1):e0228160. doi: 10.1371/journal.pone.0228160. PMID:31995604

Song K, Kwon H, Han C, Chen W, Zhang J, Ma W, Dash S, Gandhi CR, and Wu T. YAP in Kupffer cells enhances the production of cytokines and promotes the development of non-alcoholic steatohepatitis. Hepatology. 2020;72(1):72-87. PMID: 31610032

Sharma A, Verma AK, Kofron M, Kudira R, Miethke A, Wu T, Wang J, Gandhi CR. Lipopolysaccharide Reverses Hepatic Stellate Cell Activation via Modulation of cMyb, SMADs and C/EBP Transcription Factors. Hepatology. 2020 Feb 16. doi: 10.1002/hep.31188. Online ahead of print. PMID: 32064648

Dash S, Aydin Y and Wu T. Integrated stress response in hepatitis C promotes Nrf2-related chaperone-mediated autophagy: A novel mechanism for host-microbe survival and HCC development in liver cirrhosis. Semin Cell Dev Biol. 2020 May;101:20-35. doi: 10.1016/j.semcdb.2019.07.015. PMID:31386899

Yan, S., B. Khambu, X. Chen, Z. Dong, G. Guo and X. M. Yin (2020). "Hepatic Autophagy Deficiency Remodels Gut Microbiota for Adaptive Protection via FGF15-FGFR4 Signaling." Cell Mol Gastroenterol Hepatol. (https://pubmed.ncbi.nlm.nih.gov/33127558/)

Zheng, X. Z. Yang, Q. Gu, F. Xia, Y. Fu. P. Liu, X.-M. Yin and M. Li. The protease activity of human ATG4B is regulated by reversible oxidative modification. Autophagy. 16: 1838-1850, 2020 doi: 10.1080/15548627.2019.1709763, PMID: 31880198

Fu, Y, Q. Gu, L. Luo, J. Xu, Y. Luo, F. Xia, F. Han, L. Hong, X.-M. Yin, Z. Huang, and M. Li. New anti-cancer strategy to suppress colorectal cancer growth through inhibition of ATG4B and lysosomal function. Cancers. 12: 1523, 2020. 2020 Jun 10;12(6):1523. doi: 10.3390/cancers12061523.

Khambu, B. H. Hong, S. Liu, G. Liu, X. Chen, Z. Dong, J. Wan, X.-M. Yin. The HMGB-RAGE axis modulates the growth of autophagy-deficient hepatic tumors. Cell Death Dis. 2020 May 7;11(5):333. doi: 10.1038/s41419-020-2536-7. PMID: 32382012

Huang Z, D. Tian, Y. Liu, Z. Lin, C.J. Lyon, W. Lai, D. Fusco, A. Drouin, X. Yin, T. Hu, and B. Ning B. Ultra-sensitive and high-throughput CRISPR-powered COVID-19 diagnosis. Biosens Bioelectron. 164:112316, 2020. doi:10.1016/j.bios.2020.112316. PMID: 32553350

Tang, C., J. Cai, X-M. Yin, J. M., Weinberg, M.A. Venkatachalam, Z. Dong. Mitochondrial quality control in kidney injury and repair. Nat. Rev. Nephrol. 2020 Nov. 24, doi: 10.1038/s41581-020-00369-0. PMID: 33235391.

Gill CM, Orfanelli T, Yoxtheimer LM, Roy-McMahon C, Suhner J, Tomita S, Kalir T, Liu Y, Houldsworth J, Kolev V. "Histology-specific FGFR2 alterations and FGFR2-TACC2 fusion in mixed adenoid cystic and neuroendocrine small cell carcinoma of the uterine cervix." Gynecologic Oncology Reports, 2020, 100668.

Heymann JJ, Yoxtheimer LM, Park HJ, Fernandez EM, Facey KE, Alperstein SA, Tran HV, Baek I, Scognamiglio T, Rennert H, Siddiqui MT. "Preanalytic variables in quality and quantity of nucleic acids extracted from FNA specimens of thyroid gland nodules collected in CytoLyt: Cellularity and storage time." Cancer cytopathology 128.9, 2020, 656-672.

Zhang, J., Han, C., Song, K., Chen, W., Ungerleider, N., Yao, L., Ma, W. & Wu, T. The long-noncoding RNA MALAT1 regulates TGF-β/Smad signaling through formation of a lncRNA-protein complex with Smads, SETD2 and PPM1A in hepatic cells. PloS one 15, e0228160 (2020).

Ma, W., Han, C., Zhang, J., Song, K., Chen, W., Kwon, H. & Wu, T. The Histone Methyltransferase G9a Promotes Cholangiocarcinogenesis through Regulation of the Hippo Pathway Kinase LATS2 and YAP Signaling Pathway. Hepatology (2020).

Song, K., Kwon, H., Han, C., Chen, W., Zhang, J., Ma, W., Dash, S., Gandhi, C.R. & Wu, T. Yes‐Associated Protein in Kupffer Cells Enhances the Production of Proinflammatory Cytokines and Promotes the Development of Nonalcoholic Steatohepatitis. Hepatology 72, 72-87 (2020)

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Heller S, Cable C, Penrose H, Makboul R, Biswas D, Cabe M, Crawford SE, Savkovic SD: Intestinal inflammation requires FOXO3 and Prostaglandin E2 dependent lipogenesis and elevated lipid droplets. Am J Physiol Gastrointest Liver Physiol. 2016 May 15; 310 (1): G844-54. Epub: Mar 11 PMID: 26968210

Penrose H, Heller S, Cable C, Chadalawada G, Chen S, Crawford SE, Savkovic SD. Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6. Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6. PMID: 26657850

Nakanishi Y, Kanehira Y, Dibaj S, Habib F, LeVea C. Reappraisal of subserosal invasion in patients with T3 colorectal cancer: Clinicopathologic study of 129 surgical cases with special reference to peritoneal elastic laminal invasion. Arch Pathol Lab Med 2016 140(1):81-85.

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Al-Qurayshi Z, Deniwar A, Thethi T, Mallik T, Srivastav S, Murad F, Bhatia P, Moroz K, Sholl AB, Kandil E. Association of Malignancy Prevalence with Test Properties and Performance of the Gene Expression Classifier in Indeterminate Thyroid Nodules. JAMA Otolaryngol Head Neck Surg. 2016 Dec 15. [Epub ahead of print]. PMID:27978562

Blanchard A, Nguyen J, Palacios E, Vu J, Daroca P, Lewin E: Primary Mucosal Melanoma of the Larynx. Ear, Nose and Throat Journal. 2016 (Dec); 95 (12) E28.

Zhang J, Baddoo M, Han C, Strong MJ, Cvitanovic J, Moroz K, Dash S, Flemington EK, Wu T. Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma. Oncotarget. 2016 Aug 2:7(31): 49232—49245.

Deniwar A, Hammad AY, Ali DB, Alsaleh N, Lahlouh M, Sholl AB, Moroz K, Aslam R, Thethi T, Kandil E, MD. Optimal Timing for a Repeat FNA Biopsy of Thyroid Nodule Following an Initial Non-Diagnostic FNA. The American Journal of Surgery 2016 June 14. Pii: S0002-9610 (16)30289-6. 4/10/2016 Epub ahead of print.

Seijo E, Lima D, Iriabho E, Almeida J, Monico J, Echeverri M, Gutierrez S, Flores I, Lee JH, Fisher K, Grizzle WE, Sica GL, Butler C, Hicks C, Meade CD, Sodeke SO, Moroz K, Coppola D, Munoz-Antonia T. Construction and Validation of a Multi-Institutional Tissue Microarray of Invasive Ductal Carcinoma from Racially and Ethnically Diverse Populations. Cancer Control. 2016 Oct;23(4): 383-389.

Beksac M, Gragert L, Fingerson S, Maiers M, Zhang MJ, Albrecht M, Zhong X, Cozen W, Dispenzeiri A, Lonial S, Hari P. (HLA Polymorphism and Risk of Multiple Myeloma. Leukemia (2016) 30: 2260-2264.

Dehn J, Setterholm M, Buck K, Kempenich J, Beduhn B, Gragert L, Madbouly A, Fingerson S, Maiers M A Predictive HLA Matching Algorithm to Enhance Rapid Identification of the Optimal Unrelated Hematopoietic Stem Cell Sources for Transplant. Biology of Blood and Marrow Transplantation. 2016:22(11): 2038-2046.

Bochtler W, Gragert L, Patel ZI, Robinson J, Steiner D, Hofmann JA, PIngel J, Baouz A, Melis A, Schneider J, Eberhard HP, Oudshoorn M, Marsh SGE, Maiers M, Muller CR (2016) A comparative reference study for the validation of HLA-matching algorithms in the search for allogeneic hematopoietic stem cell donors and cord blood units. HLA 87(6): 439-48.

Nelson RE, Ahmad H, Hildrew DM, Lawlor C, Aslam R, Sholl AB, Kandil E. Thyroglossal duct remnant with follicular hyperplasia presenting after total thyroidectomy. Ochsner Journal, 2016; 16(2): 154-157.

Paunić V, Gragert L, Schneider J, Müller C, Maiers M. (2016) Charting Improvements in US Registry HLA Typing Ambiguity Using a Typing Resolution Score. Hum. Immunol. 77(7): 542-9.

Torikai H, Mi L, Gragert L, Maiers M, Najjar A, Ang S, Maiti S, Dai J, Switzer K, Huis H, Dulay G, Reik A, Rebar E, Holmes M, Gregory P, Champlin R, Shpall E, Cooper LJN. (2016) Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application. Sci. Rep. 2016 Feb 23; 6:21757.

Strong MJ, Blanchard E 4th, Lin Z, Morris CA, Baddoo M, Taylor CM, Ware ML, Flemington EK. A comprehensive next generation sequencing based virome assessment in brain tissue suggests no major virus - tumor association. Acta Neuropathol Commun. 2016 Jul 11;4(1):71. PubMed PMID: 27402152.

Dai L, Bai L, Lin Z, Qiao J, Yang L, Flemington EK, Zabaleta J, Qin Z. Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus. Oncotarget. 2016 Jul 26;7(30):47052-47060. PubMed PMID: 27363016.

Lin Z, Swan K, Zhang X, Cao S, Brett Z, Drury S, Strong MJ, Fewell C, Puetter A, Wang X, Ferris M, Sullivan DE, Li L, Flemington EK. Secreted Oral Epithelial Cell Membrane Vesicles Induce Epstein-Barr Virus Reactivation in Latently Infected B Cells. J Virol. 2016 Jan 13;90(7):3469-79.

R Sullivan, X Zhang, G Maresh, P Miller, L Hellmers, Z Lin, H Green, E Flemington, L Li, D Margolin. Emerging roles of microvesicles delivered by lymph node stromal cells in the pathogenesis of human colorectal cancer. 2016. Journal of Investigative Medicine. 64(2) 657-658.

Ungerleider NA, Han C, Zhang JQ, Yao L and Wu T. TGF beta signaling confers sorafenib resistance via induction of multiple RTKs in hepatocellular carcinoma cells. Molecular Carcinogenesis 2016 Nov 15, [PMID: 27862334].

Yao L, Chen WN, Han C and Wu T. Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury. Am. J. Physiol. (GI Liver Physiol). 2016, 310(11): G1071-80 [PMID: 27102561].

Kwon H, Song K, Han C, Chen W, Wang Y, Dash S, Lim K and Wu T. Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease (NAFLD). Hepatology 2016, 63(4):1155-69 [PMID: 26473743].

Dash S, Chava S, Chandra PK, Aydin Y, Balart LA and Wu T. Autophagy in hepatocellular carcinomas: from pathophysiology to therapeutic responses. Hepatic Medicine, 2016 Feb 22; 8:9-20.

Ferraris P, Chandra PK, Panigrahi R, Aboulnasr F, Chava S, Kurt R, Pawlotsky J-M, Wilkens L, Osterlund P, Hartmann R, Balart LA, Wu T and Dash S. Cellular mechanism for impaired HCV clearance by IFN associated with IL-28B gene polymorphisms relate to intrahepatic IFN-lambda expression. American J of Pathology, 2016; 186 (4):938-951.

Callaghan C, Peralta D, Liu J, Mandava SH, Maddox M, Dash S, Tarr MA and Lee B. Combined Treatment of Tyrosine Kinase Inhibitor-Labeled Gold Nanorod Encapsulated Albumin with Laser Thermal Ablation in a Renal Cell Carcinoma Model. Journal of Pharmaceutical Sciences, 2016;105:284-292.

Nelson RE, Ahmad H, Hildrew DM, Lawlor C, Aslam R, Sholl AB, Kandil E. Thyroductal remnant with follicular hyperplasia presenting after total thyroidectomy. Ochsner Journal, 2016; 16(2): 154-157.

Dash S, Chava S, Aydin Y, Chandra P, Ferraris P, Chen W, Balart LA, Wu T and Garry RF. Review: Hepatitis C virus infection induces autophagy as a pro-survival mechanism to alleviate hepatic ER-stress response. Viruses, 2016 May 23; 8(5).PMID: 27223299.

Powell D, Chandra S, Dodson K, Shaheen F, Wilt K, Ireland S, Syed M, Dash S, Weise T, Mandal T and Kundu A. Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer. European J Pharmaceutics and Biopharmaceutics, 2017 (in press). PMID: 28131717.

Roberts E, Oncale M, Safah H, and Schmieg J. 2016. Therapy-related T/myeloid mixed phenotype acute leukemia in a patient treated with chemotherapy for cutaneous diffuse large B cell lymphoma. J La State Med Soc, 168: 16-20.

Minas T, Surdez D, Taheresh J, Tanaka M, Howarth M, Kang HJ, Han J., Han ZY, Sax B, Kream BE, Hong SH, Tirode F, Tuckermann J, Toretsky T, Kenner L, Kovar H, Lee SB, Sweet-Cordero A, Nakamura T, Moriggl R, Delattre O, Uren A. Combined experience of six independent laboratories attempting to create Ewing sarcoma mouse model. Oncotarget epub . (2016). PMID: 27191748.

Lee CJ, Ahn H, Lee SB, Shin JY, Park WY, Kim JI, Lee J, Ryu H, Kim S: (Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice. BMC Medical Genomics 2016). 9(Suppl 1):33. PMID: 27534535.

Liu J, Wang M, Tulman D, Mandava SH, Elfer KN, Gabrielson A, Lai W, Abshire C, Sholl AB, Brown JQ, Lee BR. Non-Destructive Diagnosis of Kidney Cancer on 18- Gauge Core Needle Renal Biopsy Using Dual-Color Fluorescence Structured Illumination Microscopy. Urology. 2016 Dec; 98:195-199.Epub 2016 Sep 2.

Moore R, Sholl AB. Littoral cell angioma associated with extramedullary hematopoiesis and renal cell carcinoma: case report and review. Int J Clin Exp Pathol 2016;9(6):6610-6616

Wang JC, Lai WR, Traore EJ, Liu J, Sholl AB, Mandava SH, Maddox MM, Mitchell GC, Viriyasiripong S, Silberstein JL, Kittles R, Lee BR. Racial Disparities in Histology and Short-Term Renal Functional Outcomes Following Robotic Nephron-Sparing Surgery. Clin Genitourin Cancer. 2016 Jul 22. pii: S1558-7673(16)30216-6.

Liu J, Abshire C, Carry C, Sholl AB, Mandava SH, Datta A, Ranjan M, Callaghan C, Peralta DV, Williams KS, Lai WR, Abdel-Mageed AB, Tarr M, Lee BR. Nanotechnology combination therapy: Tyrosine kinase-bound gold nanorod and laser thermal ablation produce a synergistic higher treatment response of renal cell carcinoma in animal model. BJU Int. 2016 Jul 19.

Abd Elmageed ZY, Sholl AB, Tsumagari K, Al-Qurayshi Z, Basolo F, Moroz K, Boulares AH, Friedlander P, Miccoli P, Kandil E. Immunohistochemistry as an accurate tool for evaluating BRAF-V600E mutation in 130 samples of papillary thyroid cancer.Surgery. 2016 Dec 2. PMID: 27919446.

Elfer KN, Sholl AB, Wang M, Tulman DB, Mandava SH, Lee BR, Brown JQ. DRAQ5 and Eosin ('D&E') as an Analog to Hematoxylin and Eosin for Rapid Fluorescence Histology of Fresh Tissues. PLoS One. 2016 Oct 27;11(10):e0165530. PMID:27788264.

Mohamed HE, Mohamed SE, Anwar MA, Al-Qurayshi Z, Sholl AB, Thethi T, Khan A, Aslam R, Kandil E. The significance of enlarged cervical lymph nodes in diagnosing thyroid cancer. J Cancer Res Ther. 2016 Apr-Jun;12(2):1006-9.

Wang M, Tulman D, Sholl AB, Kimbrell HK, Mandava SH, Elfer K, Leuthy S, Maddox MM, Lai W, Lee BR, Brown JQ. Gigapixel surface imaging of radical prostatectomy specimens for comprehensive detection of cancer-positive surgical margins using structured illumination microscopy. Scientific Reports. 2016 Jun 3;6:27419. PMID: 27788264.

Moore R, Sholl AB, Kidd L, Al-Qurayshi Z, Tsumagari K, Emejulu O, Kholmatov R, Friedlander P, Abd Elmageed Z, Kandil E. Metadherin expression is associated with extrathyroidal extension in papillary carcinoma patients. Ann Surg Oncol. 2016 Sept 23(9):2883-8. Epub 2016 May 4. PMID: 27146414.

Feibus AH, Levy J, McCaslin IR, Doucet ME, Sholl AB, Moparty K, Thomas R, Sartor O, Silberstein JL. Racial Variation in Prostate Needle Biopsy Templates Directed at the Transition Zone. Urol Oncol. 2016 Aug(8):336.e1-6. 2016 May 5. PMID: 271555916.

Bhatia P, Deniwar A, Mohamed HE, Murad F, Sholl AB, Aslam R, Kandil E. Vanishing tumors of thyroid: histological variations after fine needle aspiration. Gland Surg. 2016; 5(3) 270-277.

Dangi A, Huang C, Tandon A, Stolz D, Wu T, Gandhi CR. Endotoxin-Stimulated Rat Hepatic Stellate Cells Induce Autophagy in Hepatocytes as a Survival Mechanism. J Cell Physiol. 2016, 231(1):94-105.

Yum E, Song K, Shin S, Kim S, Heo J, Kweon G, Wu T, Park J, Lim K. Docosahexaenoic acid suppresses breast cancer cell metastasis by targeting matrix-metalloproteinases. Oncotarget. 2016 Aug 2;7(31):49961-49971.

2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-mediated Rejection. Am J Transplant. 2016 Jun 7. doi:. PMID:2727386

Al-Qurayshi Z, Deniwar A,Thethi T, Mallik T, Srivastav S, Murad F, Bhatia P, Moroz K, Sholl AB, Kandil E. Association of Malignancy Prevalence with Test Properties and Performance of the Gene Expression Classifier in Indeterminate Thyroid Nodules.

JAMAOtolaryngol Head Neck Surg. 2016 Dec 15. Epub ahead of print. PMID: 27978562

Lewin E, Daroca P, Sikka S, Wu T, Nakanishi Y: Very well differentiated gastric adenocarcinoma of fundic gland type Case Reports in Pathology 2016; 2016: 8646927 Epub 2016 Nov 22.

Saito, Y, Bhatt, A, Nakajima, T, Sakamoto, T, Vargo, J, Yamada, M, Sekiguchi, M, Takamaru, H, Nakanishi, Y, Matsuda, Y. Colorectal endoscopic submucosal dissection (ESD) could reduce the need for surgery of colonic polyps in the West. Annals of Laparoscopic and Endoscopic Surgery, 2016 1;16. (Editorial.)

Nakanishi Y, Saxena R.. Neoplasms of the Liver and Biliary System. In: L. Cheng and Bostwick (eds.): Essentials of Anatomic Pathology. Springer, New York, 2016.

Nakanishi Y, Saxena R. Nonneoplastic Hepatobiliary Disease. In: L. Cheng and Bostwick (eds.): Essentials of Anatomic Pathology. Springer, New York, 2016. Dash S, Chava S, Aydin Y, Nakinishi Y,Buell J, Wu T, Cohen A, Balart L: Mitogen-Activated Protein Kinase (MAPK) Inhibitors for the Treatment of Advanced Hepatocellular Carcinoma. Nova Science Publishers, Hauppage, NY, 2016.

2015

Kim N, Jeong S, Jing K, Shin S, Kim S, Heo JY, Kweon GR, Park SK, Wu T, Park JI, Lim K. Docosahexaenoic Acid Induces Cell Death in Human Non-Small Cell Lung Cancer Cells by Repressing mTOR via AMPK Activation and PI3K/Akt Inhibition. Biomed Res Int. 2015;2015:239764. doi:10.1155/2015/239764. PMID: 26339598

Panigrahi R, Dash S. ENT1 and treatment of viral diseases. Oncotarget. 2015 Oct 20;6(32):32281-2. PMID: 26431496

Kimbrell HZ, Sholl AB, Ratnayaka S, Japa S, Lacey M, Carpio G, Bhatia P, Kandil E. BRAF Testing in Multifocal Papillary Thyroid Carcinoma. Biomed Res Int. 2015;2015:486391. doi: 10.1155/2015/486391. PMID: 26448939

Liu L, Liu X, Mare M, Dumont AS, Zhang H, Yan D, Xiong Z. Overexpression of Eg5 correlates with high grade astrocytic neoplasm. J Neurooncol. 2016 Jan;126(1):77-80. PMID: 26456023

Kwon H, Song K, Han C, Chen W, Wang Y, Dash S, Lim K, Wu T. Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease (NAFLD). Hepatology. 2015 Oct 16. doi: 10.1002/hep.28289. PMID: 26473743

Song K, Kwon H, Han C, Zhang J, Dash S, Lim K, Wu T. Active glycolytic metabolism in CD133(+) hepatocellular cancer stem cells: regulation by MIR-122. Oncotarget. 2015 Dec 1;6(38):40822-35. PMID: 26506419

Yang Y, Jia D, Kim H, Abd Elmageed ZY, Datta A, Davis R, Srivastav S, Moroz K, Crawford B, Moparty K, Thomas R, Hudson RS, Ambs S, Abdel-Mageed AB. Dysregulation of microRNA-212 Promotes Castration Resistance via hnRNPH1-Mediated Regulation of AR and AR-V7: Implications for Racial Disparity of Prostate Cancer. Clin Cancer Res. 2015 Nov 9. doi:pii: clincanres.1606.2015. [Epub ahead of print.] PMID: 26553749

Abdulnour-Nakhoul S, Brown KL, Rabon EC, Al-Tawil Y, Islam MT, Schmieg JJ, Nakhoul NL. Cytoskeletal changes induced by allosteric modulators of calcium-sensing receptor in esophageal epithelial cells. Physiol Rep. 2015 Nov;3(11). doi:pii: e12616. 10.14814/phy2.12616. Epub 2015 Nov 24. PMID: 26603452

Qadir XV, Chen W, Han C, Song K, Zhang J, Wu T. miR-223 Deficiency Protects against Fas-Induced Hepatocyte Apoptosis and Liver Injury through Targeting Insulin-Like Growth Factor 1 Receptor. Am J Pathol. 2015 Dec;185(12):3141-51. PMID: 26598234

Falk N, Weissferdt A, Kalhor N, Moran CA. Primary Pulmonary Salivary Gland-type Tumors: A Review and Update. Adv Anat Pathol. 2016 Jan;23(1):13-23. PMID: 26645458

Park JH, Hur W, Lee SB. Intricate Transcriptional Networks of Classical Brown and Beige Fat Cells. Front Endocrinol (Lausanne). 2015;6:124. doi: 10.3389/fendo.2015.00124. Review. PMID: 26322018

Morris GF, Danchuk S, Wang Y, Xu B, Rando RJ, Brody AR, Shan B, Sullivan DE. Cigarette smoke represses the innate immune response to asbestos. Physiol Rep. 2015 Dec;3(12). doi:pii: e12652. 10.14814/phy2.12652. PMID: 26660560

Song R, Preston G, Kidd L, Bushnell D, Sims-Lucas S, Bates CM, Yosypiv IV. Prorenin receptor is critical for nephron progenitors. Dev Biol. 2016 Jan 15;409(2):382-91. PMID: 26658320

Penrose H, Heller S, Cable C, Makboul R, Chadalawada G, Chen Y, Crawford SE, Savkovic SD. Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6. Biochem Biophys Res Commun. 2016 Jan 15;469(3):370-6. PMID: 26657850

Aboulnasr F, Hazari S, Nayak S, Chandra PK, Panigrahi R, Ferraris P, Chava S, Kurt R, Song K, Dash A, Balart LA, Garry RF, Wu T, Dash S. IFN-λ Inhibits MiR-122 Transcription through a Stat3-HNF4α Inflammatory Feedback Loop in an IFN-α Resistant HCV Cell Culture System. PLoS One. 2015;10(12):e0141655. doi: 10.1371/journal.pone.0141655. PMID: 26657215

Liu YZ, Roy-Engel AM, Baddoo MC, Flemington EK, Wang G, Wang H. The impact of oil spill to lung health-Insights from an RNA-seq study of human airway epithelial cells. Gene. 2016 Mar 1;578(1):38-51. PMID: 26692141

Nakanishi Y, LeVea C, Dibaj S, Habib F, Cheney R, Kanehira K. Reappraisal of Serosal Invasion in Patients With T3 Colorectal Cancer by Elastic Stain: Clinicopathologic Study of 139 Surgical Cases With Special Reference to Peritoneal Elastic Lamina Invasion. Arch Pathol Lab Med. 2016 Jan;140(1):81-5. PMID: 26717059

Lin Z, Swan K, Zhang X, Cao S, Brett Z, Drury S, Strong MJ, Fewell C, Puetter A, Wang X, Ferris M, Sullivan DE, Li L, Flemington EK. Secreted oral epithelial cell membrane vesicles induce Epstein-Barr virus (EBV) reactivation in latently infected B-cells. J Virol. 2016 Jan 13. doi:pii: JVI.02830-15. [Epub ahead of print.] PMID: 26764001

Strong AL, Shi Z, Strong MJ, Miller DF, Rusch DB, Buechlein AM, Flemington EK, McLachlan JA, Nephew KP, Burow ME, Bunnell BA. Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells. Environ Health Perspect. 2015 Jan;123(1):42-8. PMID: 25014179

Kurt R, Chandra PK, Aboulnasr F, Panigrahi R, Ferraris P, Aydin Y, Reiss K, Wu T, Balart LA, Dash S. Chaperone-Mediated Autophagy Targets IFNAR1 for Lysosomal Degradation in Free Fatty Acid Treated HCV Cell Culture. PLoS One. 2015 May 11;10(5):e0125962. doi: 10.1371/journal.pone.0125962. PMID: 25961570

Schubert S, Heller S, Löffler B, Schäfer I, Seibel M, Villani G, Seibel P. Generation of Rho Zero Cells: Visualization and Quantification of the mtDNA Depletion Process Int J Mol Sci. 2015 Apr 30;16(5):9850-65. PMID: 25941929

Cao S, Moss W, O'Grady T, Concha M, Strong MJ, Wang X, Yu Y, Baddoo M, Zhang K, Fewell C, Lin Z, Dong Y, Flemington EK. New Noncoding Lytic Transcripts Derived from the Epstein-Barr Virus Latency Origin of Replication, oriP, Are Hyperedited, Bind the Paraspeckle Protein, NONO/p54nrb, and Support Viral Lytic Transcription. J Virol. 2015 Jul;89(14):7120-32. PMID: 25926645

Gandhi CR, Chaillet JR, Nalesnik MA, Kumar S, Dangi A, Demetris AJ, Ferrell R, Wu T, Divanovic S, Stankeiwicz T, Shaffer B, Stolz DB, Harvey SA, Wang J, Starzl TE. Liver-specific deletion of augmenter of liver regeneration accelerates development of steatohepatitis and hepatocellular carcinoma in mice. Gastroenterology. 2015 Feb;148(2):379-391. PMID: 25448926

Park JH, Kang HJ, Lee YK, Kang H, Kim J, Chung JH, Chang JS, McPherron AC, Lee SB. Inactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasis. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6074-9. PMID: 25918410

Pineda DA, Self R, Daroca PJ, Robinson WR. Pelvic pleomorphic rhabdomyosarcoma presenting as oliguria in a 61-year-old woman. J Community Support Oncol. 2015 Mar;13(3):120-1. PMID: 25880675

McCarty TP, Lee RA, Herfel BM, Pappas PG. Cytomegalovirus appendicitis in solid organ transplant patients, two cases and a review. J Clin Virol. 2015 May;66:48-50. Review. PMID: 25866336

Song K, Han C, Dash S, Balart LA, Wu T. MiR-122 in hepatitis B virus and hepatitis C virus dual infection. World J Hepatol. 2015 Mar 27;7(3):498-506. Review. PMID: 25848473

Deniwar A, Hambleton C, Thethi T, Moroz K, Kandil E. Examining the Bethesda criteria risk stratification of thyroid nodules. Pathol Res Pract. 2015 May;211(5):345-8. PMID: 2579629

Chen W, Han C, Zhang J, Song K, Wang Y, Wu T. Deletion of Mir155 prevents Fas-induced liver injury through up-regulation of Mcl-1. Am J Pathol. 2015 Apr;185(4):1033-44. PMID: 25794705

Peralta DV, Heidari Z, Dash S, Tarr MA. Hybrid paclitaxel and gold nanorod-loaded human serum albumin nanoparticles for simultaneous chemotherapeutic and photothermal therapy on 4T1 breast cancer cells. ACS Appl Mater Interfaces. 2015 Apr 8;7(13):7101-11. PMID: 25768122

Ibrahim Y, Mohamed SE, Deniwar A, Al-Qurayshi ZH, Khan AN, Moroz K, Friedlander P, Kandil E. The impact of thyroid nodule size on the risk of malignancy in follicular neoplasms. Anticancer Res. 2015 Mar;35(3):1635-9. PMID: 25750321

Yao L, Han C, Song K, Zhang J, Lim K, Wu T. Omega-3 Polyunsaturated Fatty Acids Upregulate 15-PGDH Expression in Cholangiocarcinoma Cells by Inhibiting miR-26a/b Expression. Cancer Res. 2015 Apr 1;75(7):1388-98. PMID: 25691459

Ibrahim Y, Crawford BE, Murci M, Masoodi H, Khan AN, Hu T, Kandil E, Friedlander P. Thyroid cancer in black thyroid glands: the effect of age and race. RL J Otorhinolaryngol Relat Spec. 2015;77(1):33-8. PMID: 25661419

Panigrahi R, Chandra PK, Ferraris P, Kurt R, Song K, Garry RF, Reiss K, Coe IR, Furihata T, Balart LA, Wu T, Dash S. Persistent hepatitis C virus infection impairs ribavirin antiviral activity through clathrin-mediated trafficking of equilibrative nucleoside transporter 1. J Virol. 2015 Jan;89(1):626-42. PMID: 25339775

Mader EC Jr, Richeh W, Ochoa JM, Sullivan LL, Gutierrez AN, Lovera JF. Tumefactive multiple sclerosis and hepatitis C virus 2a/2C infection: Dual benefit of long-term interferon beta-1a therapy? J Neurol Sci. 2015 Feb 15;349(1-2):239-42. PMID: 25575859

Comparison of sorafenib-loaded poly (lactic/glycolic) acid and DPPC liposome nanoparticles in the in vitro treatment of renal cell carcinoma. Liu J, Boonkaew B, Arora J, Mandava SH, Maddox MM, Chava S, Callaghan C, He J, Dash S, John VT, Lee BR. J Pharm Sci. 2015 Mar;104(3):1187-96. PMID: 25573425

Li Y, Liu J, Li W, Brown A, Baddoo M, Li M, Carroll T, Oxburgh L, Feng Y, Saifudeen Z. p53 Enables metabolic fitness and self-renewal of nephron progenitor cells. Development. 2015 Apr 1;142(7):1228-41. PMID: 25804735

Park JH, Lee SB. An essential role for Ewing sarcoma gene (EWS) in early white adipogenesis. Obesity (Silver Spring). 2015 Jan;23(1):138-44. PMID: 25407167

Cao S, Strong MJ, Wang X, Moss WN, Concha M, Lin Z, O'Grady T, Baddoo M, Fewell C, Renne R, Flemington EK. High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol. 2015 Jan;89(1):713-29. PMID: 25355872

Cope JR, Ratard RC, Hill VR, Sokol T, Causey JJ, Yoder JS, Mirani G, Mull B, Mukerjee KA, Narayanan J, Doucet M, Qvarnstrom Y, Poole CN, Akingbola OA, Ritter JM, Xiong Z, da Silva AJ, Roellig D, Van Dyke RB, Stern H, Xiao L, Beach MJ. The first association of a primary amebic meningoencephalitis death with culturable Naegleria fowleri in tap water from a US treated public drinking water system. Clin Infect Dis. 2015 Apr 15;60(8):e36-42. doi: 10.1093/cid/civ017. PMID: 25595746

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