Section of Pulmonary Diseases, Critical Care and Environmental Medicine
Faculty Publications: July 1, 2023 – June 30, 2024
JOSEPH LASKY, MD
Sydney B. Montesi, Dana Ball, Bill Schmidt, Michael Beers, Robert Brown, Ishanu Chattopadhyay, Cory Hogaboam, Kevin Flaherty, Christine Garcia, Brigitte Gomperts, Lida Hariri, Naftali Kaminski, Grace Kim, Melanie Koenigshoff, Martin Kolb, Darrell Kotton, Jonathan Kropski, Joseph Lasky, Chelsea Magin, Toby Maher, Mark McCormick, Bethany Moore, Justin Oldham, Anna Podolanczuk, Ganesh Raghu, Ivan Rosas, Steven Rowe, David Schwartz, Jessica Shore, Cathie Spino, Matthew Craig, Fernando J. Martinez. Pulmonary Fibrosis Stakeholder Summit: A Joint National Heart, Lung, and Blood Institute, Three Lakes Foundation, and Pulmonary Fibrosis Foundation Workshop Report, Am J Respir Crit Care Med. 2023 Dec 19.
Ganesh Raghu, Marya Ghazipura, Thomas R Fleming, Kerri I Aronson, Jürgen Behr, Kevin, K Brown, Kevin R Flaherty, Ella A Kazerooni, Toby M Maher, Luca Richeldi, Joseph A Lasky, Jeffrey J Swigris, Robert Busc, Lili Garrard 14, Dong-Hyun Ahn, Ji Li, Khalid, Puthawala, Gabriela Rodal, Sally Seymour, Nargues Weir, Sonye K Danoff, Neil, Ettinger, Jonathan Goldin, Marilyn K Glassberg, Leticia Kawano, Nasreen Khalil, Lisa, Lancaster, David A Lynch, Yolanda Mageto, Imre Noth, Jessica E Shore, Marlies, Wijsenbeek, Robert Brown, Daniel Grogan, Dot Ivey, Patrycja Golinska, Banu Karimi-Shah, and Fernando Martinez. Meaningful Endpoints for Idiopathic Pulmonary Fibrosis (IPF) Clinical Trials: Prioritizing Feels, Functions, Survives, Am J Respir Crit Care Med. 2024 Jan 4.
Christopher S. King, MD; Rosalinda V. Ignacio, MS; Vikramjit Khangoora, MD; Alan Nyquist, MD; Anju Singhal, MD; Christopher Thomas, MD; Onix Fonseca Cantres, MD; Shambhu Aryal, MD; Oksana A. Shlobin, MD; Kevin Flaherty, MD; Joseph Lasky, MD; MD; Steven D. Nathan, MD. Hospitalization Rates in Interstitial Lung Disease: An Analysis of the Pulmonary Fibrosis Foundation Registry, Am J Respir Crit Care Med. 2024 Jan 18.
Fayez Kheir, Ramsy Abdelghani, Diana Espinoza, Regina Villalobos, David Becnel, Rachel Herr, Alejandro Aragaki, Joseph A. Lasky. Impact of the Envisia Genomic Classifier in Patients with Undiagnosed Interstitial Lung Disease, in press, Chest.
Francesco Lombardi , Iain Stewart , Laura Fabbri , Wendy Adams , Leticia Kawano-Dourado, Christopher J Ryerson, Gisli Jenkins ; REMAP-ILD Consortium (Lasky JA). Mycophenolate and azathioprine efficacy in interstitial lung disease: a systematic review and meta-analysis. BMJ Open Respir Res, 2024 Feb 27;11(1).
Kawano-Dourado L, Kulkarni T, Ryerson CJ, Rivera-Ortega P, Baldi BG, Chaudhuri N, Funke-Chambour M, Hoffmann-Vold AM, Johannson KA, Khor YH, Montesi SB, Piccari L, Prosch H, Molina-Molina M, Sellares Torres J, Bauer-Ventura I, Rajan S, Jacob J, Richards D, Spencer LG, Wendelberger B, Jensen T, Quintana M, Kreuter M, Gordon AC, Martinez FJ, Kaminski N, Cornelius V, Lewis R, Adams W, Jenkins G; REMAP-ILD consortium (Lasky JA). Adaptive multi-interventional trial platform to improve patient care for fibrotic interstitial lung disease. Thorax. 2024 Mar 6:thorax-2023-221148.
JAY KOLLS, MD
Clark RDE, Rabito F, Munyonho FT, Remcho TP, Kolls JK. Evaluation of anti- vector immune responses to adenovirus-mediated lung gene therapy and modulation by αCD20. Mol Ther Methods Clin Dev. 2024 Jun 24;32(3):101286. doi: 10.1016/j.omtm.2024.101286. PMID: 39070292; PMCID: PMC11283059.
Currey J, Ellsworth C, Khatun MS, Wang C, Chen Z, Liu S, Midkiff C, Xiao M, Ren M, Liu F, Elgazzaz M, Fox S, Maness NJ, Rappaport J, Lazartigues E, Blair R, Kolls JK, Mauvais-Jarvis F, Qin X. Upregulation of inflammatory genes and pathways links obesity to severe COVID-19. Biochim Biophys Acta Mol Basis Dis. 2024 Jun 26;1870(7):167322. doi: 10.1016/j.bbadis.2024.167322. Epub ahead of print. PMID: 38942338.
Castro-Pando S, Howell RM, Li L, Mascaro M, Faraoni EY, Le Roux O, Romanin D, Tahan V, Riquelme E, Zhang Y, Kolls JK, Allison JP, Lozano G, Moghaddam SJ, McAllister F. Pancreatic epithelial IL-17/IL-17RA signaling drives B7-H4 expression to promote tumorigenesis. Cancer Immunol Res. 2024 Jun 6. doi: 10.1158/2326-6066.CIR-23-0527. Epub ahead of print. PMID: 38842383.
Ellsworth CR, Wang C, Katz AR, Chen Z, Islamuddin M, Yang H, Scheuermann SE, Goff KA, Maness NJ, Blair RV, Kolls JK, Qin X. Natural Killer Cells Do Not Attenuate a Mouse-Adapted SARS-CoV-2-Induced Disease in Rag2-/- Mice. Viruses. 2024 Apr 15;16(4):611. doi: 10.3390/v16040611. PMID: 38675952; PMCID: PMC11054502.
Qadir MMF, Elgamal RM, Song K, Kudtarkar P, Sakamuri SSVP, Katakam PV, El- Dahr S, Kolls J, Gaulton KJ, Mauvais-Jarvis F. Single cell regulatory architecture of human pancreatic islets suggests sex differences in β cell function and the pathogenesis of type 2 diabetes. bioRxiv [Preprint]. 2024 Jun 11:2024.04.11.589096. doi: 10.1101/2024.04.11.589096. PMID: 38645001; PMCID: PMC11030320.
Hoffmann JP, Srivastava A, Yang H, Iwanaga N, Remcho TP, Hewes JL, Sharoff R, Song K, Norton EB, Kolls JK, McCombs JE. Vaccine-elicited IL-1R signaling results in Th17 TRM-mediated immunity. Commun Biol. 2024 Apr 9;7(1):433. doi: 10.1038/s42003-024-06138-0. PMID: 38594380; PMCID: PMC11003962.
Tong S, Scott JC, Eyoh E, Werthmann DW, Stone AE, Murrell AE, Sabino-Santos G, Trinh IV, Chandra S, Elliott DH, Smira AR, Velazquez JV, Schieffelin J, Ning B, Hu T, Kolls JK, Landry SJ, Zwezdaryk KJ, Robinson JE, Gunn BM, Rabito FA, Norton EB. Altered COVID-19 immunity in children with asthma by atopic status. J Allergy Clin Immunol Glob. 2024 Feb 29;3(2):100236. doi: 10.1016/j.jacig.2024.100236. PMID: 38590754; PMCID: PMC11000189.
Yang H, Iwanaga N, Katz AR, Ridley AR, Miller HD, Allen MJ, Pociask D, Kolls JK. Embigin Is Highly Expressed on CD4+ and CD8+ T Cells but Is Dispensable for Several T Cell Effector Responses. Immunohorizons. 2024 Mar 1;8(3):242-253. doi: 10.4049/immunohorizons.2300083. PMID: 38446446; PMCID: PMC10985056.
Taghavi S, Engelhardt D, Campbell A, Goldvarg-Abud I, Duchesne J, Shaheen F, Pociask D, Kolls J, Jackson-Weaver O. Dimethyl sulfoxide as a novel therapy in a murine model of acute lung injury. J Trauma Acute Care Surg. 2024 Jul 1;97(1):32-38. doi: 10.1097/TA.0000000000004293. Epub 2024 Mar 6. PMID: 38444065.
Abdulnour-Nakhoul SM, Kolls JK, Flemington EK, Ungerleider NA, Nakhoul HN, Song K, Nakhoul NL. Alterations in gene expression and microbiome composition upon calcium-sensing receptor deletion in the mouse esophagus. Am J Physiol Gastrointest Liver Physiol. 2024 Apr 1;326(4):G438-G459. doi: 10.1152/ajpgi.00066.2023. Epub 2024 Jan 9. PMID: 38193195; PMCID: PMC11213479.
Harrison MAA, Morris SL, Rudman GA, Rittenhouse DJ, Monk CH, Sakamuri SSVP, Mehedi Hasan M, Shamima Khatun M, Wang H, Garfinkel LP, Norton EB, Kim S, Kolls JK, Jazwinski SM, Mostany R, Katakam PVG, Engler-Chiurazzi EB, Zwezdaryk KJ. Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice. Brain Behav Immun. 2024 Mar;117:36-50. doi: 10.1016/j.bbi.2023.12.033. Epub 2024 Jan 3. PMID: 38182037.
Huckestein BR, Zeng K, Westcott R, Alder JK, Antos D, Kolls JK, Alcorn JF. Mammalian Target of Rapamycin Complex 1 Activation in Macrophages Contributes to Persistent Lung Inflammation following Respiratory Tract Viral Infection. Am J Pathol. 2024 Mar;194(3):384-401. doi: 10.1016/j.ajpath.2023.11.017. Epub 2023 Dec 28. PMID: 38159723; PMCID: PMC10913760.
Chandra V, Li L, Le Roux O, Zhang Y, Howell RM, Rupani DN, Baydogan S, Miller HD, Riquelme E, Petrosino J, Kim MP, Bhat KPL, White JR, Kolls JK, Pylayeva-Gupta Y, McAllister F. Gut epithelial Interleukin-17 receptor A signaling can modulate distant tumors growth through microbial regulation. Cancer Cell. 2024 Jan 8;42(1):85-100.e6. doi: 10.1016/j.ccell.2023.12.006. Epub 2023 Dec 28. PMID: 38157865; PMCID: PMC11238637.
Munyonho FT, Clark RDE, Lin D, Khatun MS, Pungan D, Dai G, Kolls JK. Precision-cut lung slices as an ex vivo model to study Pneumocystis murina survival and antimicrobial susceptibility. mBio. 2024 Jan 16;15(1):e0146423. doi: 10.1128/mbio.01464-23. Epub 2023 Dec 20. PMID: 38117035; PMCID: PMC10790776.
Wang C, Khatun MS, Zhang Z, Allen MJ, Chen Z, Ellsworth CR, Currey JM, Dai G, Tian D, Bach K, Yin XM, Traina-Dorge V, Rappaport J, Maness NJ, Blair RV, Kolls JK, Pociask DA, Qin X. COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes. Commun Biol. 2023 Dec 13;6(1):1265. doi: 10.1038/s42003-023-05626-z. PMID: 38092883; PMCID: PMC10719262.
Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann S, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle- Meyers LA, Schiro F, Aye PP, Lifson JD, Beddingfield BJ, Blair RV, Bohm RP, Kolls JK, Rappaport J, Hoxie JA, Maness NJ. The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection. bioRxiv [Preprint]. 2023 Nov 16:2023.11.15.567132. doi: 10.1101/2023.11.15.567132. Update in: Viruses. 2024 Jul 21;16(7):1173. doi: 10.3390/v16071173. PMID: 38014096; PMCID: PMC10680717.
Hu Y, Bojanowski CM, Britto CJ, Wellems D, Song K, Scull C, Jennings S, Li J, Kolls JK, Wang G. Aberrant immune programming in neutrophils in cystic fibrosis. J Leukoc Biol. 2024 Feb 23;115(3):420-434. doi: 10.1093/jleuko/qiad139. PMID: 37939820.
Taghavi S, Campbell A, Engelhardt D, Duchesne J, Shaheen F, Pociask D, Kolls J, Jackson-Weaver O. Dimethyl malonate protects the lung in a murine model of acute respiratory distress syndrome. J Trauma Acute Care Surg. 2024 Mar 1;96(3):386-393. doi: 10.1097/TA.0000000000004184. Epub 2023 Nov 8. PMID: 37934622; PMCID: PMC10922501.
Lu S, Chen K, Song K, Pilewski JM, Gunn BM, Poch KR, Rysavy NM, Vestal BE, Saavedra MT, Kolls JK. Systems serology in cystic fibrosis: Anti-Pseudomonas IgG1 responses and reduced lung function. Cell Rep Med. 2023 Oct 17;4(10):101210. doi: 10.1016/j.xcrm.2023.101210. PMID: 37852181; PMCID: PMC10591031.
Khatun MS, Remcho TP, Qin X, Kolls JK. Cell-intrinsic and -extrinsic effects of SARS-CoV-2 RNA on pathogenesis: single-cell meta-analysis. mSphere. 2023 Oct 24;8(5):e0037523. doi: 10.1128/msphere.00375-23. Epub 2023 Sep 22. PMID: 37737611; PMCID: PMC10597400.
Beppu AK, Zhao J, Yao C, Carraro G, Israely E, Coelho AL, Drake K, Hogaboam CM, Parks WC, Kolls JK, Stripp BR. Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection. Nat Commun. 2023 Sep 19;14(1):5814. doi: 10.1038/s41467-023-41387-3. PMID: 37726288; PMCID: PMC10509177.
Alam MA, Caocci M, Ren M, Chen Z, Liu F, Khatun MS, Kolls JK, Qin X, Burdo TH. Deficiency of Caspase-1 Attenuates HIV-1-Associated Atherogenesis in Mice. Int J Mol Sci. 2023 Aug 17;24(16):12871. doi: 10.3390/ijms241612871. PMID: 37629052; PMCID: PMC10454548.
Landry SJ, Mettu RR, Kolls JK, Aberle JH, Norton E, Zwezdaryk K, Robinson J. Structural Framework for Analysis of CD4+ T-Cell Epitope Dominance in Viral Fusion Proteins. Biochemistry. 2023 Sep 5;62(17):2517-2529. doi: 10.1021/acs.biochem.3c00335. Epub 2023 Aug 9. PMID: 37554055; PMCID: PMC10483696.
Ponde NO, Shoger KE, Khatun MS, Sarkar MK, Dey I, Taylor TC, Cisney RN, Arunkumar SP, Gudjonsson JE, Kolls JK, Gottschalk RA, Gaffen SL. SARS-CoV-2 ORF8 Mediates Signals in Macrophages and Monocytes through MyD88 Independently of the IL-17 Receptor. J Immunol. 2023 Jul 15;211(2):252-260. doi: 10.4049/jimmunol.2300110. PMID: 37265402; PMCID: PMC10330444.
Taghavi S, Abdullah S, Shaheen F, Packer J, Duchesne J, Braun SE, Steele C, Pociask D, Kolls JK, Jackson-Weaver O. EXOSOMES AND MICROVESICLES FROM ADIPOSE- DERIVED MESENCHYMAL STEM CELLS PROTECTS THE ENDOTHELIAL GLYCOCALYX FROM LPS INJURY. Shock. 2023 Jul 1;60(1):56-63. doi: 10.1097/SHK.0000000000002133. Epub 2023 Apr 22. PMID: 37086080.
DAVID JANZ, MD
Noninvasive Ventilation for Preoxygenation during Emergency Intubation.
Gibbs KW, Semler MW, Driver BE, Seitz KP, Stempek SB, Taylor C, Resnick-Ault D, White HD, Gandotra S, Doerschug KC, Mohamed A, Prekker ME, Khan A, Gaillard JP, Andrea L, Aggarwal NR, Brainard JC, Barnett LH, Halliday SJ, Blinder V, Dagan A, Whitson MR, Schauer SG, Walker JE Jr, Barker AB, Palakshappa JA, Muhs A, Wozniak JM, Kramer PJ, Withers C, Ghamande SA, Russell DW, Schwartz A, Moskowitz A, Hansen SJ, Allada G, Goranson JK, Fein DG, Sottile PD, Kelly N, Alwood SM, Long MT, Malhotra R, Shapiro NI, Page DB, Long BJ, Thomas CB, Trent SA, Janz DR, Rice TW, Self WH, Bebarta VS, Lloyd BD, Rhoads J, Womack K, Imhoff B, Ginde AA, Casey JD; PREOXI Investigators and the Pragmatic Critical Care Research Group. N Engl J Med. 2024 Jun 20;390(23):2165-2177. doi: 10.1056/NEJMoa2313680. Epub 2024 Jun 13. PMID: 38869091 Clinical Trial.
Validation of a Novel, Rapid Sepsis Diagnostic for Emergency Department Use.
O'Neal HR Jr, Sheybani R, Janz DR, Scoggins R, Jagneaux T, Walker JE, Henning DJ, Rosenman E, Mahler SA, Regunath H, Sampson CS, Files DC, Fremont RD, Noto MJ, Schneider EE, Shealey WR, Berlinger MS, Carver TC, Walker MK, Ledeboer NA, Shah AM, Tse HTK, DiCarlo D, Rice TW, Thomas CB. Crit Care Explor. 2024 Feb 7;6(2):e1026. doi: 10.1097/CCE.0000000000001026. eCollection 2024 Feb. PMID: 38333076 Free PMC article.
Prophylactic Administration of Vasopressors Prior to Emergency Intubation in Critically Ill Patients: A Secondary Analysis of Two Multicenter Clinical Trials. Fuchita M, Pattee J, Russell DW, Driver BE, Prekker ME, Barnes CR, Brewer JM, Doerschug KC, Gaillard JP, Gandotra S, Ghamande S, Gibbs KW, Hughes CG, Janz DR, Khan A, Mitchell SH, Page DB, Rice TW, Self WH, Smith LM, Stempek SB, Trent SA, Vonderhaar DJ, West JR, Whitson MR, Williamson K, Semler MW, Casey JD, Ginde AA. Crit Care Explor. 2023 Jul 12;5(7):e0946. doi: 10.1097/CCE.0000000000000946. eCollection 2023 Jul.PMID: 37457916 Free PMC article.
Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults.
Prekker ME, Driver BE, Trent SA, Resnick-Ault D, Seitz KP, Russell DW, Gaillard JP, Latimer AJ, Ghamande SA, Gibbs KW, Vonderhaar DJ, Whitson MR, Barnes CR, Walco JP, Douglas IS, Krishnamoorthy V, Dagan A, Bastman JJ, Lloyd BD, Gandotra S, Goranson JK, Mitchell SH, White HD, Palakshappa JA, Espinera A, Page DB, Joffe A, Hansen SJ, Hughes CG, George T, Herbert JT, Shapiro NI, Schauer SG, Long BJ, Imhoff B, Wang L, Rhoads JP, Womack KN, Janz DR, Self WH, Rice TW, Ginde AA, Casey JD, Semler MW; DEVICE Investigators and the Pragmatic Critical Care Research Group. N Engl J Med. 2023 Aug 3;389(5):418-429. doi: 10.1056/NEJMoa2301601. Epub 2023 Jun 16.PMID: 37326325 Free PMC article. Clinical Trial.
Discordance Between Invasive and NonInvasive Oxygen Saturation in Critically Ill COVID-19 Patients. Fox TH, Mazalewski WR, Tran HS, Lindsey T, Krishnan A, Kantrow SP, Happel KI, Janz DR, deBoisblanc BP, Lammi MR. J Intensive Care Med. 2023 Dec;38(12):1151-1157. doi: 10.1177/08850666231186947. Epub 2023 Jul 7. PMID: 37415515 Free PMC article.
Defining Successful Intubation on the First Attempt Using Both Laryngoscope and Endotracheal Tube Insertions: A Secondary Analysis of Clinical Trial Data. Trent SA, Driver BE, Prekker ME, Barnes CR, Brewer JM, Doerschug KC, Gaillard JP, Gibbs KW, Ghamande S, Hughes CG, Janz DR, Khan A, Mitchell SH, Page DB, Rice TW, Russell DW, Self WH, Smith LM, Stempek S, Vonderhaar DJ, West JR, Whitson MR, Ginde AA, Casey JD, Semler MW.
Ann Emerg Med. 2023 Oct;82(4):432-437. doi: 10.1016/j.annemergmed.2023.03.021. Epub 2023 Apr 18. PMID: 37074254 Free PMC article.
Laryngoscopy and Tracheal Intubation: Does Use of a Video Laryngoscope Facilitate Both Steps of the Procedure?
Prekker ME, Trent SA, Lofrano A, Russell DW, Barnes CR, Brewer JM, Doerschug KC, Gaillard JP, Gandotra S, Ginde AA, Ghamande S, Gibbs KW, Hughes CG, Janz DR, Khan A, Mitchell SH, Page DB, Rice TW, Self WH, Smith LM, Stempek SB, Vonderhaar DJ, West JR, Whitson MR, Casey JD, Semler MW, Driver BE.
Ann Emerg Med. 2023 Oct;82(4):425-431. doi: 10.1016/j.annemergmed.2023.02.016. Epub 2023 Apr 5. PMID: 37028995 Free PMC article.
ANIL MISHRA, Ph.D.
Kandikattu, H. K., Venkateshaiah, S. U., Kumar, S., Yadavalli, C. S., & Mishra, A. (2023). IL-18-mediated neutrophil recruitment promotes acute lung injury in inflammation-mediated chronic pancreatitis. Molecular immunology, 155, 100-109
Yadavalli, C. S., Upparahalli Venkateshaiah, S., Kumar, S., Kandikattu, H. K., Oruganti, L., Kathera, C. S., & Mishra, A. (2023). Allergen-induced NLRP3/caspase1/IL-18 signaling initiate eosinophilic esophagitis and respective inhibitors protect disease pathogenesis. Communications Biology, 6(1), 763.
Kandikattu, H. K., Venkateshaiah, S. U., Yadavalli, C. S., Oruganti, L., & Mishra, A. (2023). Development and Characterization of Novel Chronic Eosinophilic Inflammation-Mediated Murine Model of Malignant Pancreatitis. Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders), 23(10), 1303-1317.
Yadavalli, C. S., Upparahalli Venkateshaiah, S., Verma, A. K., Kathera, C., Duncan, P. S., Vaezi, M., ... & Mishra, A. (2024). Vasoactive Intestinal Peptide Receptor, CRTH2, Antagonist Treatment Improves Eosinophil and Mast Cell-Mediated Esophageal Remodeling and Motility Dysfunction in Eosinophilic Esophagitis. Cells, 13(4), 295.
BRIAN DESKIN, Ph.D.
Rehan M, Deskin B, Kurundkar AR, Yadav S, Matsunaga Y, Manges J, Smith N, Dsouza KG, Burow ME, Thannickal VJ. Nicotinamide N-methyltransferase mediates lipofibroblast-myofibroblast transition and apoptosis resistance. J Biol Chem. 2023 Aug;299(8):105027. doi: 10.1016/j.jbc.2023.105027. Epub 2023 Jul 7. PMID: 37423298; PMCID: PMC10413354.
YONG ZHOU, Ph.D.
Zhou Y*, Thannickal VJ. Demystifying the Enigmatic Fibroblast in Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2023 Jul;69(1):1-2
Hu Q, Saleem K, Pandey J, Charania A, Zhou Y, He C. Cell Adhesion Molecules in Fibrotic Diseases. Biomedicines 2023 Jul 14;11(7):1995. doi: 10.3390/biomedicines11071995.
Shan D, Hu Q, He C, Zhou Y. Editorial: Targeting immune cell metabolism in tissue fibrosis. Frontiers in Pharmacology 2024 Apr 5;15:1400858. doi: 10.3389/fphar.2024.1400858.
Zheng Z, Peng F, Zhou Y. Biomarkers in Idiopathic Pulmonary Fibrosis: Current Insights and Future Directions. Chin Med J Pulm Crit Care Med (invited review). 2024 Jun;2(2):72-79.
ZHEN ZHENG, Ph.D.
Zheng Z, Peng F, Zhou Y. Biomarkers in idiopathic pulmonary fibrosis: Current insight and future direction. Chin Med J Pulm Crit Care Med. 2024 Jun;2(2):72-79. doi: 10.1016/j.pccm.2024.04.003. Epub 2024 Jun 14. PMID: 38962100; PMCID: PMC11221783.
Zheng Z, Peng F, Zhou Y. Pulmonary fibrosis: A short- or long-term sequelae of severe COVID-19? Chin Med J Pulm Crit Care Med. 2023 Jun;1(2):77-83. doi: 10.1016/j.pccm.2022.12.002. Epub 2023 Jan 23. PMID: 37388822 Free PMC article.
DEEPAK TRIPATHI, Ph.D.
Yang B, Mukherjee T, Radhakrishnan R, Paidipally P, Ansari D, John S, Vankayalapati R, Tripathi D*, Yi G. HIV-Differentiated Metabolite N-Acetyl-L-Alanine Dysregulates Human Natural Killer Cell Responses to Mycobacterium tuberculosis Infection. Int J Mol Sci. 2023 Apr 14;24(8):7267. doi: 10.3390/ijms24087267. PMID: 37108430; PMCID: PMC10138430. *Co-corresponding author.
CHAD ROY, Ph.D.
Current vaccine strategies and novel approaches to combatting Francisella infection. Harrell JE, Roy CJ, Gunn JS, McLachlan JB. Vaccine. 2024 Apr 2;42(9):2171-2180. doi: 10.1016/j.vaccine.2024.02.086. Epub 2024 Mar 8. PMID: 38461051
MVA-based vaccines are protective against lethal eastern equine encephalitis virus aerosol challenge in cynomolgus macaques. Beddingfield BJ, Plante KS, Plante JA, Weaver SC, Bose S, Krzykwa C, Chirichella N, Redmann RK, Seiler SZ, Dufour J, Blair RV, Endt K, Volkmann A, Maness NJ, Roy CJ.NPJ Vaccines. 2024 Feb 27;9(1):47. doi: 10.1038/s41541-024-00842-y. PMID: 38413593
DEREK POCIASK, Ph.D.
IL-22 Binding Protein Controls IL-22-Driven Bleomycin-Induced Lung Injury. Zhang Z, Chakawa MB, Galeas-Pena M, Frydman JA, Allen MJ, Jones M, Pociask D. Am J Pathol. 2024 Mar;194(3):338-352. doi: 10.1016/j.ajpath.2023.11.011. Epub 2023 Dec 14. PMID: 38101567
COVID-19 and influenza infections mediate distinct pulmonary cellular and transcriptomic changes. Wang C, Khatun MS, Zhang Z, Allen MJ, Chen Z, Ellsworth CR, Currey JM, Dai G, Tian D, Bach K, Yin XM, Traina-Dorge V, Rappaport J, Maness NJ, Blair RV, Kolls JK, Pociask DA, Qin X. Commun Biol. 2023 Dec 13;6(1):1265. doi: 10.1038/s42003-023-05626-z. PMID: 38092883
Dimethyl malonate protects the lung in a murine model of acute respiratory distress syndrome. Taghavi S, Campbell A, Engelhardt D, Duchesne J, Shaheen F, Pociask D, Kolls J, Jackson-Weaver O. J Trauma Acute Care Surg. 2024 Mar 1;96(3):386-393. doi: 10.1097/TA.0000000000004184. Epub 2023 Nov 8. PMID: 37934622
ROSS KLINGSBERG, MD
Safety and efficacy of vanzacaftor-tezacaftor-deutivacaftor in adults with cystic fibrosis: randomised, double-blind, controlled, phase 2 trials. Uluer AZ, MacGregor G, Azevedo P, Indihar V, Keating C, Mall MA, McKone EF, Ramsey BW, Rowe SM, Rubenstein RC, Taylor-Cousar JL, Tullis E, Yonker LM, Chu C, Lam AP, Nair N, Sosnay PR, Tian S, Van Goor F, Viswanathan L, Waltz D, Wang LT, Xi Y, Billings J, Horsley A; VX18-121-101; VX18-561-101 Study Groups. Lancet Respir Med. 2023 Jun;11(6):550-562. doi: 10.1016/S2213-2600(22)00504-5. Epub 2023 Feb 23. PMID: 36842446
CHRISTINE BOJANOWSKI, MD
Sweeney PL, Morrison DG, Bojanowski CM. Staphylococcus aureus Induced Purpura Fulminans. Am J Med Sci. 2024 Jan 13: S0002-9629 (24) 00007-7. Online ahead of print. PMID: 38219983
Hu Y, Bojanowski CM, Britto CJ, Wellems D, Song K, Scull C, Jennings S, Li J, Kolls JK, Wang G. Aberrant Immune Programming in Neutrophils in Cystic Fibrosis. J Leukoc Biol. 2023 Nov 6:qiad139. Online ahead of print. PMID: 37939820.
Okoli S, Jenkins K, Bojanowski CM. Current Intensive Care Management of Thrombotic Thrombocytopenic Purpura: A Case Report and Updated Literature Review. J Intensive Care Medicine. 2023 Jul; 38 (7):592-597. Doi: 10.1177/08850666231171907. Epub 2023 Jun 18. PMID: 37331965
Cited As An Investigator:
Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial. O'Halloran JA, Ko ER, Anstrom KJ, Kedar E, McCarthy MW, Panettieri RA Jr, Maillo M, Nunez PS, Lachiewicz AM, Gonzalez C, Smith PB, de Tai SM, Khan A, Lora AJM, Salathe M, Capo G, Gonzalez DR, Patterson TF, Palma C, Ariza H, Lima MP, Blamoun J, Nannini EC, Sprinz E, Mykietiuk A, Alicic R, Rauseo AM, Wolfe CR, Witting B, Wang JP, Parra-Rodriguez L, Der T, Willsey K, Wen J, Silverstein A, O'Brien SM, Al-Khalidi HR, Maldonado MA, Melsheimer R, Ferguson WG, McNulty SE, Zakroysky P, Halabi S, Benjamin DK Jr, Butler S, Atkinson JC, Adam SJ, Chang S, LaVange L, Proschan M, Bozzette SA, Powderly WG; ACTIV-1 IM Study Group Members.JAMA. 2023 Jul 25;330(4):328-339. doi: 10.1001/jama.2023.11043.PMID: 37428480 Free PMC article.
Abatacept Pharmacokinetics and Exposure Response in Patients Hospitalized With COVID-19: A Secondary Analysis of the ACTIV-1 IM Randomized Clinical Trial. Balevic SJ, Benjamin DK Jr, Powderly WG, Smith PB, Gonzalez D, McCarthy MW, Shaw LK, Lindsell CJ, Bozzette S, Williams D, Linas BP, Blamoun J, Javeri H, Hornik CP; ACTIV-1 IM Study Group.JAMA Netw Open. 2024 Apr 1;7(4):e247615. doi: 10.1001/jamanetworkopen.2024.7615.PMID: 38662372 Free PMC article. Clinical Trial.
HIMMAT GREWAL, MD
Asymptomatic Metastatic Pleural Calcifications from End-Stage Renal Disease. Lee NM, Ferrell S, Grewal H. R I Med J (2013). 2023 Jul 5;106(6):21-22. PMID: 37368829
The Relationship Between Metabolic Syndrome and Mortality Among Patients With Acute Respiratory Distress Syndrome in Acute Respiratory Distress Syndrome Network and Prevention and Early Treatment of Acute Lung Injury Network Trials. Tea K, Zu Y, Chung CH, Pagliaro J, Espinoza-Barrera D, Mehta P, Grewal H, Douglas IS, Khan YA, Shaffer JG, Denson JL. Crit Care Med. 2024 Mar 1;52(3):407-419. doi: 10.1097/CCM.0000000000006092. Epub 2023 Nov 1. PMID: 37909824
From detection to disappearance: A tale of a nodule. Herr R, Grewal H, Abdelghani R. Respir Med Case Rep. 2024 Jun 5;50:102059. doi: 10.1016/j.rmcr.2024.102059. eCollection 2024. PMID: 39021870
JERRY ZIFODYA, MD
HIV and diabetes impair M. tuberculosis-specific interferon-gamma responses on QuantiFERON-TB Gold Plus testing. J S Zifodya 1 , J S Kreniske 2 , T M Temu 3 , S J Masyuko 3 , E F Attia 3 4 , J N Mogaka 5 , D Onyango 6 , S T Page 7 , K Crothers 4 8 , J Kinuthia 9 , C Farquhar 3 10 11 , S M LaCourse 3 10 11 Affiliations. PMID: 39022782 PMCID: PMC11249601 DOI: 10.5588/ijtldopen.24.0011
JOSHUA DENSON, MD
Financial Education in U.S. Pulmonary and Critical Care Medicine Fellowship Programs. Krutsinger DC, Adamson R, Olson EM, Denson JL, Kelm DJ, Chu DC, Stewart NH. ATS Sch. 2023 Sep 29;4(3):302-306. doi: 10.34197/ats-scholar.2023-0005BR. eCollection 2023 Sep. PMID: 37795115
Association Between Hypertension and Diabetes Control and COVID-19 Severity: National Patient-Centered Clinical Research Network, United States, March 2020 to February 2022. Jackson SL, Woodruff RC, Nagavedu K, Fearrington J, Rolka DB, Twentyman E, Carton TW, Puro J, Denson JL, Kappelman MD, Paranjape A, Thacker D, Weiner MG, Goodman AB, Lekiachvili A, Boehmer TK, Block JP; PCORnet Collaboration Authors *. J Am Heart Assoc. 2023 Nov 7;12(21):e030240. doi: 10.1161/JAHA.122.030240. Epub 2023 Oct 18. PMID: 37850404
The Relationship Between Metabolic Syndrome and Mortality Among Patients With Acute Respiratory Distress Syndrome in Acute Respiratory Distress Syndrome Network and Prevention and Early Treatment of Acute Lung Injury Network Trials. Tea K, Zu Y, Chung CH, Pagliaro J, Espinoza-Barrera D, Mehta P, Grewal H, Douglas IS, Khan YA, Shaffer JG, Denson JL. Crit Care Med. 2024 Mar 1;52(3):407-419. doi: 10.1097/CCM.0000000000006092. Epub 2023 Nov 1. PMID: 37909824
Systematic review of the effect of metabolic syndrome on outcomes due to acute respiratory distress syndrome: a protocol. Stone G, Sisk A, Brown M, Corder A, Tea K, Zu Y, Shaffer J, Kashyap R, Qadir N, Denson JL. BMJ Open. 2023 Nov 10;13(11):e076036. doi: 10.1136/bmjopen-2023-076036. PMID: 37949623
The Association of Asthma and Metabolic Dysfunction With Outcomes of Hospitalized Patients With COVID-19. Vukoja M, Tekin A, Parada NA, Gray JC, Mallouhi A, Roddy T, Cartin-Ceba R, Perkins NE, Belden KA, Cheruku S, Kaufman M, Lee Armaignac D, Christie AB, Lal A, Zu Y, Kumar V, Walkey A, Gajic O, Kashyap R, Denson JL; Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. J Allergy Clin Immunol Pract. 2024 May 23:S2213-2198(24)00539-7. doi: 10.1016/j.jaip.2024.05.025. Online ahead of print. PMID: 38796103
NEREIDA PARADA, MD
Biologic outcomes in US Hispanic and Black patients with severe asthma. Trevor J, Moore WC, Lugogo N, Ledford DK, Mackie A, Carstens D, Parada NA, Ambrose CS. J Allergy Clin Immunol Pract. 2024 Jun 18:S2213-2198(24)00643-3. doi: 10.1016/j.jaip.2024.06.020. Online ahead of print. PMID: 38901615
The Association of Asthma and Metabolic Dysfunction With Outcomes of Hospitalized Patients With COVID-19. Vukoja M, Tekin A, Parada NA, Gray JC, Mallouhi A, Roddy T, Cartin-Ceba R, Perkins NE, Belden KA, Cheruku S, Kaufman M, Lee Armaignac D, Christie AB, Lal A, Zu Y, Kumar V, Walkey A, Gajic O, Kashyap R, Denson JL; Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. J Allergy Clin Immunol Pract. 2024 May 23:S2213-2198(24)00539-7. doi: 10.1016/j.jaip.2024.05.025. Online ahead of print. PMID: 38796103
RAMSY ABDELGHANI, MD
Imaging modalities during navigational bronchoscopy. Abdelghani R, Omballi M, Abia-Trujillo D, Casillas E Jr, Villalobos R, Badar F, Bansal S, Kheir F. Expert Rev Respir Med. 2024 Mar-Apr;18(3-4):175-188. doi: 10.1080/17476348.2024.2359601. Epub 2024 May 29. PMID: 3879491
From detection to disappearance: A tale of a nodule. Herr R, Grewal H, Abdelghani R. Respir Med Case Rep. 2024 Jun 5;50:102059. doi: 10.1016/j.rmcr.2024.102059. eCollection 2024. PMID: 39021870
SHIGEKI SAITO, MD
STOP-Bang for OSA screening in patients with pulmonary hypertension. Fox TH, LaNasa M, Saketkoo LA, Saito S, deBoisblanc BP, Lammi MR. Respir Med. 2023 Oct;217:107339. doi: 10.1016/j.rmed.2023.107339. Epub 2023 Jul 5. PMID: 37419376
VICTOR THANNICKAL, MD
Demystifying the Enigmatic Fibroblast in Pulmonary Fibrosis.
Zhou Y, Thannickal VJ. Am J Respir Cell Mol Biol. 2023 Jul;69(1):1-2. doi: 10.1165/rcmb.2023-0090ED. PMID: 37040483
Nicotinamide N-methyltransferase mediates lipofibroblast-myofibroblast transition and apoptosis resistance.
Rehan M, Deskin B, Kurundkar AR, Yadav S, Matsunaga Y, Manges J, Smith N, Dsouza KG, Burow ME, Thannickal VJ. J Biol Chem. 2023 Aug;299(8):105027. doi: 10.1016/j.jbc.2023.105027. Epub 2023 Jul 7. PMID: 37423298
The lung mesenchyme in development, regeneration, and fibrosis.
El Agha E, Thannickal VJ. J Clin Invest. 2023 Jul 17;133(14):e170498. doi: 10.1172/JCI170498. PMID: 37463440
Small Extracellular Vesicle Signaling and Mitochondrial Transfer Reprograms T Helper Cell Function in Human Asthma. Hough KP, Trevor JL, Chacko BK, Strenkowski JG, Wang Y, Goliwas KF, Bone NB, Kim YI, Holmes R, Vang S, Pritchard A, Chin J, Bodduluri S, Antony VB, Tousif S, Athar M, Chanda D, Mitra K, Zmijewski J, Zhang J, Duncan SR, Thannickal VJ, Gabrielsson S, Darley-Usmar VM, Deshane JS. bioRxiv [Preprint]. 2024 May 3:2024.04.30.589227. doi: 10.1101/2024.04.30.589227. PMID: 38746361
YASIN KHAN, MD
Retraction Note: The COVID-19 pandemic and its impact on environment: the case of the major cities in Pakistan. Khan YA. Environ Sci Pollut Res Int. 2024 Mar;31(15):23288. doi: 10.1007/s11356-024-32886-x. PMID: 38472592
The Relationship Between Metabolic Syndrome and Mortality Among Patients With Acute Respiratory Distress Syndrome in Acute Respiratory Distress Syndrome Network and Prevention and Early Treatment of Acute Lung Injury Network Trials. Tea K, Zu Y, Chung CH, Pagliaro J, Espinoza-Barrera D, Mehta P, Grewal H, Douglas IS, Khan YA, Shaffer JG, Denson JL. Crit Care Med. 2024 Mar 1;52(3):407-419. doi: 10.1097/CCM.0000000000006092. Epub 2023 Nov 1. PMID: 37909824
