Protein folding and protein-protein interactions; molecular chaperone proteins; antigen processing.
Our work employs biochemical and biophysical techniques to investigate structure/function relationships in protein-protein interactions, especially those involved in cellular stress and immune responses.
Mechanism of Hsp60/Hsp10 Chaperonin Specificity: Chaperonins are a class of stress-induced molecular chaperones characterized by a ring-shaped oligomeric structure and the distinctive ability to use ATP to promote protein folding. Our studies aim to illuminate mechanistic...
