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Hui Shen, PhD
  • Professor, Division of Biomedical Informatics & Genomics
  • Associate Director, Center for Biomedical Informatics & Genomics
  •  
  • hshen3@tulane.edu
  • 1440 Canal Street, Suite 1621, New Orleans, LA 70112
  • (504) 988-6987
  • School of Medicine
Hui Shen, PhD

Education

  • Postdoc, Yale University
  • PhD, Creighton University
  • BS, University of Science and Technology of China

Biography

Hui Shen is a geneticist with specific training and expertise in genomics and epigenomics of human complex disorders. His current research interests focus mainly on identifying and characterizing genetic and epigenetic variation that affects susceptibility to complex human disorders, such as osteoporosis and sarcopenia. He is now expanding his research area into the cutting-edge metagenomics of osteoporosis and sarcopenia. He teaches BINF 7500 Epigenetics and Epigenomics and BINF 7010 Population and Quantitative Genetics. Prior to joining the faculty at Tulane, he was an assistant professor at University of Missouri-Kansas City and a postdoctoral researcher at Yale University. He received his doctor of philosophy in human genetics from the Creighton University and his bachelor of science in molecular biology from University of Science and Technology of China.

Memberships

  • Member, American Society of Human Genetics (ASHG)
  • Member, American Society for Bone and Mineral Research (ASBMR)

Level of Instruction:

graduate

Research

  • Genomics Epigenomics Metagenomics of human complex disorders Center Section: Epigenomics My research interests are mainly focused on identifying and characterizing genetic and epigenetic variation that affects susceptibility to complex human disorders, such as osteoporosis and sarcopenia. Toward these ends, we are integrating multidisciplinary approaches including genetic epidemiology, functional genomics, epigenomics, proteomics, bioinformatics, and molecular biology. We recently performed an epidgenome-wide MeDIP sequencing (MeDIP-Seq) study to identify differentially methylated regions associated with osteoporosis. We also performed several pioneering sequencing-based projects, including a whole genome sequencing study and an exome sequencing project for osteoporosis in different ethnic groups, using the next-generation sequencing technologies. The successful identification and characterization of genetic and epigenetic variations underlying osteoporosis and sarcopenia will markedly increasing our understanding of disease pathophysiology and may lead to novel and individualized treatment.

    • Interests

    Genomics, Epigenomics, Metagenomics of human complex disorders

    Publications

    View Dr. Shen's publications at his NCBI profile page.

    Research

  • Genomics Epigenomics Metagenomics of human complex disorders Center Section: Epigenomics My research interests are mainly focused on identifying and characterizing genetic and epigenetic variation that affects susceptibility to complex human disorders, such as osteoporosis and sarcopenia. Toward these ends, we are integrating multidisciplinary approaches including genetic epidemiology, functional genomics, epigenomics, proteomics, bioinformatics, and molecular biology. We recently performed an epidgenome-wide MeDIP sequencing (MeDIP-Seq) study to identify differentially methylated regions associated with osteoporosis. We also performed several pioneering sequencing-based projects, including a whole genome sequencing study and an exome sequencing project for osteoporosis in different ethnic groups, using the next-generation sequencing technologies. The successful identification and characterization of genetic and epigenetic variations underlying osteoporosis and sarcopenia will markedly increasing our understanding of disease pathophysiology and may lead to novel and individualized treatment.

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