Song Hong, PhD
Associate Professor of Research, Neuroscience and Ophthalmology
Education & Affiliations
Biography
Positions
2012-present: Associate Professor of Neuroscience and Ophthalmology.
Neuroscience Center of Excellence,
LSU Health Sciences Center, New Orleans, LA
2006-2012: Assistant Professor of Neuroscience and Ophthalmology.
Neuroscience Center of Excellence,
LSU Health Sciences Center, New Orleans, LA
2004-2006: Instructor, Harvard Medical School, Boston, MA
2001-2004: Research fellow, Harvard Medical School, Boston, MA
Current Research:
1) Our major objective is to elucidate new mechanisms and explore the therapeutic potential of endogenous reparative lipid mediators that contribute to the restoration of wound reinnervation and healing in diabetes. Our studies include the biochemical metabolic pathways and signaling of lipid mediators in diabetic wounds and burn injury. We intend to decipher the roles of novel lipid mediators in the key cellular and molecular processes including inflammation, innervation, phagocytosis/efferocytosis, vascularization/angiogenesis, epithelialization, and fibrosis. 2) We are also developing novel hydrogels, nanoparticles, and microparticles for wound healing and nerve regeneration by collaboration with biomaterial scientists.
Research
- Wound healing
- chronic wounds impaired by diabetes and aging
- diabetic neuropathy
- nerve regeneration and degeneration
Publications
Key Peer-reviewed Publications
(Selected from 62 peer-reviewed publications)
1. Nishimura, K.; Sakaguchi, T.; Nanba, Y.; Suganuma, Y.; Morita, M.; Hong, S.; Lu, Y.; Jun, B.; Bazan, N. G.; Arita, M.; Kobayashi, Y., Stereoselective Total Synthesis of Macrophage-Produced Prohealing 14,21-Dihydroxy Docosahexaenoic Acids. The Journal of organic chemistry. 2018; 83(1):154-166. PMID: 29224348.
2. Bazan, H. A.; Lu, Y.; Jun, B.; Fang, Z.; Woods, T. C.; Hong, S.*, Circulating inflammation-resolving lipid mediators RvD1 and DHA are decreased in patients with acutely symptomatic carotid disease. Prostaglandins, leukotrienes, and essential fatty acids. 2017; 125:43-47. PMID: 28987721 PMCID: PMC5909403.
3. Alapure, B. V.; Lu, Y.; Peng, H.; Hong, S.*, Surgical denervation of specific cutaneous nerves impedes excisional wound healing of small animal ear pinnae.Mol Neurobiol, 2017, Jan 21. PMID: 28110472.
4. Hong, S. *; Tian, H.; Lu, Y.; Laborde, J. M.; Muhale, F. A.; Wang, Q.; Alapure, B. V.; Serhan, C. N.; Bazan, N. G., Neuroprotectin/Protectin D1: Endogenous Biosynthesis and Actions on Diabetic Macrophages in Promoting Wound Healing and Innervation Impaired by Diabetes. Am J Physiol Cell Physiol, 2014, 307, (11): C1058-67. PMCID: PMC4254953. PMID: 25273880.
5. Hong, S.*; Lu, Y.; Tian, H.; Alapure, B. V.; Wang, Q.; Bonnell, B.; Laborde, J. M., Leukocytes and Platelets Produce Novel Maresin-like Docosanoids Structure, Biosynthesis, and Effect on Diabetes-impaired Macrophage Reparative Function. Chemistry & Biology (Cell at Cell Press), 2014, 21, (10): 1318-29. PMCID: PMC4224612. PMID:25200603.
