Borrelia burgdorferi and Lyme disease specializes in animal models and is centered around three major efforts: (1) identifying treatments that can eradicate B. burgdorferi infection; (2) identification of Lyme disease spirochetes in human tissues; and (3) immunodiagnosis for B. burgdorferi infection and cure. The first research goal is to use animal models of persistent infection to evaluate new therapeutic strategies. The second goal is to evaluate humans for persistent infection with B. burgdorferi. The third goal is to develop a...
