Louise B. Lawson, PhD

With a focus on infectious disease, Dr. Lawson studies novel formulations for delivery of vaccines and antimicrobials, as well as bacterial pathogenesis. Through her work in this area, she developed a particular interest in determining sex differences in severity of bacterial infections of the intestinal tract. A better understanding of sex differences in disease sensitivity will allow for design of more informed and personalized treatment and preventive options for patients suffering with diarrheal disease and other toxin-mediated conditions caused by bacterial pathogens.

Research Interests

With a focus on infectious disease, Dr. Lawson studies novel formulations for delivery of vaccines and antimicrobials, as well as bacterial pathogenesis. Work in her laboratory has explored formulations for transdermal, intradermal and sublingual vaccine delivery, and pulmonary and transpapillary drug delivery. Another aspect of her research is encapsulation and delivery of antimicrobials for tailored release over time. Polymer- and gelatin-based films offer the capability to control the release of therapeutic agents over time to extend their effectiveness. This has led to more recent work on formulations that inhibit and even eradicate microbial biofilms. By understanding particular permeation pathways and cellular interactions, tailored formulations to maximize protection and treatment of infectious disease can be developed.

Through her work in bacterial pathogenesis, Dr. Lawson developed a particular interest in determining sex differences in severity of bacterial infections of the intestinal tract. A better understanding of sex differences in disease sensitivity will allow for design of more informed and personalized treatment and preventive options for patients suffering with diarrheal disease and other toxin-mediated conditions caused by bacterial pathogens.

Dr. Lawson also values her involvement with undergraduate, graduate, and medical students both in the classroom and research lab. Merging her scientific training with educational endeavors, she has developed an interest in educational scholarship with a focus on the impact of active learning strategies and laboratory-based learning opportunities.