Education & Affiliations
Biography
Appointment and Position
2007-2008: Science Librarian, University of New Orleans, New Orleans, LA
2008-2011: Basic Sciences and Bioinformatics Librarian, Mount Sinai School of Medicine, New York, NY
2013-2016: Ruth L. Kirschstein NRSA Predoctoral Fellow, Tulane University School of Medicine, New Orleans, LA
2016-2021: Postdoctoral Fellow and FNRS Chargé de Recherches, GIGA Institute, University of Liège, Liège, Belgium
Publications
O'Grady T. 2007. Entrez and BLAST: precision and recall in searches of NCBI databases. Issues in Science and Technology Librarianship 52.
O’Grady T. 2008. Bioinformatics: a brief review of resources on the web. College & Research Libraries News 69(7):404.
O’Grady T and Beam P. 2011. Postdoctoral scholars: a forgotten library constituency? Science &Technology Libraries 30(1):76.
Makarov V, O’Grady T, Cai G, Lihm J, Buxbaum JD and Yoon S. 2012. AnnTools: a comprehensive and versatile annotation toolkit for genomic variants. Bioinformatics 28(5):724.
Strong MJ, O’Grady T, Lin Z, Xu G, Baddoo M, Parsons C, Zhang K, Taylor CM and Flemington EK.2013. Epstein-Barr Virus and Human Herpesvirus 6 detection in a non-Hodgkin's diffuse large B-cell lymphoma cohort by using RNA sequencing. Journal of Virology 87(23):13059.
O’Grady T, Cao S, Strong MJ, Concha M, Wang X, BonDurant SS, Adams M, Baddoo M, Srivastav S, Lin Z, Fewell C, Yin Q and Flemington EK. 2014. Global bidirectional transcription of the Epstein-Barr virus genome during reactivation. Journal of Virology 88(3):1604.
Cao S, Strong MJ, Wang X, Moss WN, Concha M, Lin Z, O’Grady T, Baddoo M, Fewell C, Renne Rand Flemington EK. 2015. High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia Project. Journal of Virology 89(1):713.
Cao S, Moss W, O’Grady T, Concha M, Strong MJ, Wang X, Yu Y, Baddoo M, Zhang K, Fewell C, Lin Z, Dong Y and Flemington EK. 2015. New noncoding lytic transcripts derived from the Epstein-Barr virus latency origin of replication, oriP, are hyperedited, bind the paraspeckle protein, NONO/p54nrb,and support viral lytic transcription. Journal of Virology 89(14):7120.
O’Grady T, Wang X, Höner zu Bentrup K, Baddoo M, Concha M and Flemington EK. 2016. Global transcript structure resolution of high gene density genomes through multi-platform data integration. Nucleic Acids Research 44(18):e145.
O’Grady T, Baddoo M and Flemington EK. 2017. Analysis of EBV transcription using high-throughput RNA sequencing. Methods in Molecular Biology 1532:102.
Théry C, … , O’Grady T, … , and Zuba-Surma EK. 2018. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. Journal of Extracellular Vesicles7(1):1535750.
Kara M, O’Grady T, Feldman ER, Flemington EK and Tibbetts SA. 2019. Gammaherpesvirus readthrough transcription generates a long noncoding RNA that is regulated by antisense miRNAs and correlates with enhanced lytic replication in vivo. Non-coding RNA 5(1):6.
O’Grady T, Feswick A, Hoffman B, Wang Y, Medina EM, Kara M, van Dyck LF, Flemington EK and Tibbetts S. 2019. Genome-wide transcript structure resolution reveals abundant alternate isoform usage from murine gammaherpesvirus 68. Cell Reports 27:3988-4002.
Veloso A, Martin M, Bruyr J, O’Grady T, Deroanne C, Mottet D, Twizere JC, Cherrier T, Dequiedt F. 2019. Dephosphorylation of HDAC4 by PP2A-Bd unravels a new role for the HDAC4/MEF2 axis in myoblast fusion. Cell Death & Disease 10:512.
Saulnier O, Guedri-Idjouadiene K, Aynaud MM, Chakraborty A, Bruyr J, Pineau J, O’Grady T,Mirabeau O, Grosstête S, Galvan B, Claes M, Al Oula Hassoun Z, Sadacca B, Laud K, Zaïdi S,Surdez D, Baulande S, Rambout X, Tirode F, Dutertre M, Delattre O and Dequiedt F. 2021. ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in theEWS-FLI1 oncogenic fusion. Nucleic Acids Research 49(9):5083.
