Dr. Zhuo is a Professor of Physiology in the Departments of Physiology and the Director of Tulane Hypertension and Renal Center of Excellence (THRCE) at Tulane University School of Medicine, New Orleans, Louisiana. He joined Tulane University School of Medicine from the University of Mississippi Medical Center, where he served as a tenured professor and the Director of Receptor and Signal Transduction Laboratory in the Department of Pharmacology and Toxicology. Dr. Zhuo received a Doctor of Medicine degree (M.D.) from Guangxi Medical University, Nanning, China in 1983, and a Ph.D. degree in renal physiology and hypertension from the Department of Physiology at the University of Melbourne, Victoria, Australia in 1990. He served as a National Health and Medical Research Council of Australia Senior Research Officer at the Austin and Repatriation Medical Center and Howard Florey Institute of Experimental Physiology and Medicine at the University of Melbourne from 1993 to 2000, and a Senior Staff Investigator in the Hypertension and Vascular Research Division at Henry Ford Hospital, Detroit, Michigan from 2001 to 2010. Dr. Zhuo has 30 years’ sponsored research investigating the roles of circulating (endocrine), tissue (paracrine), and intracellular (intracrine) angiotensin II and its receptor mapping and signaling mechanisms in renal physiology and hypertension. His research has been continuously supported by grants from the National Health and Medical Research Council (NH&MRC) of Australia, American Heart Association (AHA), American Society of Nephrology (ASN), and National Institute of Health (NIH). As one of the renowned experts in the intratubular renin-angiotensin research field, Dr. Zhuo is a regular invited national and international speaker; and has published over 115 peer-reviewed journal articles and book chapters. He is an elected Fellow of the American Association for the Advancement of Science (FAAAS), Section on Medical Sciences, Overseas Fellow of Royal Society of Medicine (FRSM), England, and a Fellow of American Heart Association (FAHA) and American Society of Nephrology (FASN), respectively. Dr. Zhuo was the past Chair of the American Physiological Society (APS) Physiological Genomics Group, a permanent member for NIH/Center for Scientific Review Hypertension and Microcirculation Study Section, and Ad Hoc reviewer for NH&MRC of Australia, Chinese Ministry of Education, and Danish Council for Independent Research. His research is currently supported by several grants from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
Dr. Zhuo’s laboratory is interested in studying the roles of endocrine (tissue-to-tissue), paracrine (cell-to-cell), and intracrine (endosomal, mitochondrial and nuclear) angiotensin II (ANG II) and its G protein-coupled receptor (GPCR) signal mechanisms in the proximal tubules of the kidney and blood pressure control. Supported by several grants from the NIDDK, the laboratory currently investigates: 1) the molecular and signaling mechanisms by which circulating and paracrine ANG II is taken up by the proximal tubule of the kidney to act as an intracellular peptide; 2) high resolution...
Publications for Dr. Jia 'Joe' Zhuo.
