Dr. Zhang received a bachelor degree in biology from Shaanxi Normal University, China in 1987. She was appointed assistant professor at Shaanxi University of Chinese Medicine in 1987 and was promoted to lecturer in 1994 and associate professor in 2002. Dr. Zhang received a master of science degree in 2001 and a PhD degree in 2004 from Xi’an Jiaotong University School of Medicine and then joined the faculty there as an associate professor in the Department of Anatomy and Histology and Embryology. In 2005, she started her postdoctoral training in molecular biology at Eastern New Mexico University and then in cancer genetics at Loyola University in Chicago. In 2006, Dr. Zhang joined George Washington University as a research scientist in the Department of Biochemistry and Molecular Biology. In 2009, she joined Tulane University School of Medicine as a postdoctoral fellow in molecular cancer biology in the Department of Structural & Cellular Biology. She was promoted to be an instructor in 2014 and assistant professor in 2018. Dr. Zhang’s research interests include reproductive biology, cancer biology, and inflamm-aging.
Inflamm-aging and prostate cancer
Zhang Q, Liu S, Ge D, Cunningham DM, Huang F, Ma L, Burris TP, You Z. Targeting Th17-IL-17 pathway in prevention of micro-invasive prostate cancer in a mouse model. The Prostate 2017; 77(8):888-899. PMID: 28240383.
Zhang Q, Liu S, Parajuli KR, Mo Z, Liu J, Chen Z, Yang S, Wang AR, Myers L, You Z. Interleukin-17 Promotes Prostate Cancer via MMP7-Induced Epithelial-to-Mesenchymal Transition. Oncogene 2017; 36(5), 687-699. PMID: 27375020.
Liu S, Zhang Q, Chen C, Ge D, Qu Y, Chen R, Fan YM, Li N, Tang WW, Zhang W, Zhang K, Wang A, Rowan BG, Hill, SM, Sartor O, Abdel-Mageed AB, Myers L, Lin Q, You Z. Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor. Oncotarget 2016; 7(12): 13651-66. PMID: 26871944, PMCID: PMC4924668.
Zhang Q, Liu S, Zhang Q, Xiong Z, Wang AR, Myers L, Melamed J, Tang WW, You Z. Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment. Prostate 2014; 74:869-879. PMID: 24691769.
Zhang Q, Liu S, Ge D, Zhang QS, Xue Y, Xiong Z, Abdel-Mageed AB, Myers L, Hill SM, Rowan BG, Sartor O, Melamed J, Chen Z, You Z. Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse models. Cancer Res 2012; 72(10): 2589-2599. PMID: 22461511, PMCID: PMC3665158.
Zhang Q, Cigan AD, Marrero L, Lopreore C, Liu S, Ge D, Savoie FH, You Z. Expression of doublecortin reveals articular chondrocyte lineage in mouse embryonic limbs. Genesis 2011; 49(2): 75-82. PMID: 21162077
Zhang J, Tian H, Huo YW, Zhou DX, Wang HX, Wang LR, Zhang QY, Qui SD. The expression of Usp26 in male mouse testis and brain. Asian J Androl, Jun 8, 2009; 1-6. PMID: 19503076
Zhang Q, Wu J, Nguyen A, Wang BD, He P, Laurent GS, Rennert OM, Su YA. Molecular Mechanisms Underlying Differential Apoptosis Between Human Melanoma Cell Lines UACC903 and UACC903 (+6) Revealed by Mitochondria-Focused cDNA Microarray. Apoptosis 2008; 13(8):993-1004. PMID: 18563568
Zhang Q, Chen Y, Wang BD, He P, Su YA. Differences in Apoptosis and Cell Cycle Distribution Between Human Melanoma Cell Lines UACC903 and UACC903 (+6) Before and After UV Irradiation. Int J Biol Sci 2007; 3(6): 342-48. PMID: 17657283
Zhang J. Li SB, Zhou DX, Tian H, Huo YW, Ge L, Zhang QY, Qiu SD. Novel mutations in testis-specific ubiquitin protease 26 genes may cause spermatogenesis impairment and male infertility. Asian J Androl 2007; 9(6): 809-14. PMID: 15970005