Sangkyu Kim, Ph.D.

Assistant Professor

Department of Medicine Tulane Center for Aging Tulane University Health Sciences Center
School of Medicine
Department
Tulane Center Aging
Sangkyu Kim, PhD

Education & Affiliations

Ph.D. in Yeast Genetics ‐ University of Iowa, Iowa City, Iowa (1991)
Postdoctoral Research in Yeast Cell Cycle Control ‐ University Arizona, Tucson, Arizona (1991 ‐ 1994)
Postdoctoral Research in Yeast Replicative Aging ‐ LSU Health Sciences Center, New Orleans, LA (1995 ‐ 1998)
Postdoctoral Research in Genetics of Human Aging ‐ LSU Health Sciences Center & Tulane University, New Orleans, LA (2004 ‐ 2009)

Research

  • Biology of Aging
  • Genetics and Epigenetics of Aging
  • Multi-Omics of Aging
  • Predictive Modeling of Aging

Research Projects

  • Sphingolipid Biology in the Budding Yeast (American Heart Association, 2001 ‐ 2003)
  • Genetics of Longevity in Long-Lived Siblings (K01, 2007 ‐ 2011)
  • Genetics of Longevity in Georgia Centenarian Study (P01, Program director: Dr. Lenny Poon)
  • Louisiana Healthy Aging Study (P01, Program director: Dr. S. Michal Jazwinski)
  • Healthy Aging Twin Study (COBRE Project 3, NIGMS, 2012-2017)
  • Epigenetics in Tg2576 Alzheimer’s Model Mice (COBRE Pilot Project, 2019-2020)
  • Multi-Omics of Healthy Aging in Rhesus Monkeys (The Brown Foundation, 2020-2021)

Contributions

Kim S, Fuselier J, Welsh DA, Cherry KE, Myers L, Jazwinski SM. Feature selection algorithms enhance the accuracy of frailty indexes as measures of biological age. J Gerontol A Biol Sci Med Sci. 2021 Jan 20;. doi: 10.1093/gerona/glab018. [Epub ahead of print] PubMed PMID: 33471059.

Kim S, Wyckoff J, Morris AT, Succop A, Avery A, Duncan GE, Jazwinski SM. DNA methylation associated with healthy aging of elderly twins. Geroscience. 2018 Dec;40(5-6):469-484. doi: 10.1007/s11357-018-0040-0. Epub 2018 Aug 22. PubMed PMID: 30136078; PubMed Central PMCID: PMC6294724.

Kim S, Jazwinski SM. The Gut Microbiota and Healthy Aging: A Mini-Review. Gerontology. 2018;64(6):513-520. doi: 10.1159/000490615. Epub 2018 Jul 19. Review. PubMed PMID: 30025401; PubMed Central PMCID: PMC6191326.

Maffei VJ, Kim S, Blanchard E 4th, Luo M, Jazwinski SM, Taylor CM, Welsh DA. Biological Aging and the Human Gut Microbiota. J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1474-1482. doi: 10.1093/gerona/glx042. PubMed PMID: 28444190; PubMed Central PMCID: PMC5861892.

Kim S, Myers L, Wyckoff J, Cherry KE, Jazwinski SM. The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age. Geroscience. 2017 Feb;39(1):83-92. doi: 10.1007/s11357-017-9960-3. Epub 2017 Jan 14. PubMed PMID: 28299637; PubMed Central PMCID: PMC5352589.

Kim S, Myers L, Ravussin E, Cherry KE, Jazwinski SM. Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians. Biogerontology. 2016 Aug;17(4):725-36. doi: 10.1007/s10522-016-9643-y. Epub 2016 Mar 10. PubMed PMID: 26965008; PubMed Central PMCID: PMC4935613.

Kim S, Simon E, Myers L, Hamm LL, Jazwinski SM. Programmed Cell Death Genes Are Linked to Elevated Creatine Kinase Levels in Unhealthy Male Nonagenarians. Gerontology. 2016;62(5):519-29. doi: 10.1159/000443793. Epub 2016 Feb 26. PubMed PMID: 26913518; PubMed Central PMCID: PMC4993668.

Kim S, Welsh DA, Myers L, Cherry KE, Wyckoff J, Jazwinski SM. Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival. Oncotarget. 2015 Feb 28;6(6):3600-12. doi: 10.18632/oncotarget.2877. PubMed PMID: 25682868; PubMed Central PMCID: PMC4414140.

Kim S, Jazwinski SM. Quantitative measures of healthy aging and biological age. Healthy Aging Res. 2015;4. doi: 10.12715/har.2015.4.26. PubMed PMID: 26005669; PubMed Central PMCID: PMC4440677.

Kim S, Welsh DA, Ravussin E, Welsch MA, Cherry KE, Myers L, Jazwinski SM. An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively. J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):650-6. doi: 10.1093/gerona/glt150. Epub 2013 Oct 25. PubMed PMID: 24162336; PubMed Central PMCID: PMC4022095.

Kim S, Welsh DA, Cherry KE, Myers L, Jazwinski SM. Association of healthy aging with parental longevity. Age (Dordr). 2013 Oct;35(5):1975-82. doi: 10.1007/s11357-012-9472-0. Epub 2012 Sep 18. PubMed PMID: 22986583; PubMed Central PMCID: PMC3776103.