Jill M. Daniel, PhD

Gary P. Dohanich Professor in Brain Science, Professor of Psychology, Director of the Tulane Brain Institute

School of Science and Engineering
School of Science & Engineering
Department
Tulane Center Aging
TIPS Mentor
J. Daniel

Courses

Brain and Behavior PSYC 330 / NSCI 330
Neurobiology of Learning and Memory PSYC 633 / NSCI 633

Research

  • Psychology / neurosciences
  • Cognitive aging
  • Hormonal influences on aging

The broad goal of Dr. Daniel’s research is to understand mechanisms by which estrogens and androgens impact areas of the brain important for cognition. Current work in the lab is focused on the impact of these hormones on the brain and cognition across the lifespan, from early in development during which they help organize mammalian brains as male or female to later in life during which changes in their levels impact the aging brain. Research is conducted in rodent models and experimental approaches used in the lab include behavioral analyses as well as biochemical and molecular assays.

Contributions

Grissom, E.M. & Daniel, J.M. (2016). Evidence for ligand-independent activation of hippocampal estrogen receptor alpha by insulin-like growth factor-1 in hippocampus of ovariectomized rats Endocrinology, [Epub ahead of print].

Bayless, D.W. & Daniel, J.M. (2015). Sex differences in myelin-associated protein levels within and density of projections between the orbital frontal cortex and dorsal striatum of adult rats: implications for inhibitory control. Neuroscience, 300: 286-296.

Daniel, J.M., Witty, C. F., Rodgers, S. P. (2015). Long-term consequences of estrogens administered in midlife on female cognitive aging. Invited review in Special Issue, Estradiol and Cognition: Molecules to Mind, Hormones and Behavior, 74: 77-85.

Bayless, D. W., Perez, M. C., Daniel, J. M. (2015). Comparison of the validity of the use of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder in males and females. Behavioural Brain Research, 286: 85-92.

Nelson, B.S, Springer, R.C. & Daniel, J.M.  (2014). Antagonism of brain insulin-like growth factor-1 receptors blocks estradiol effects on memory and levels of hippocampal synaptic proteins in ovariectomized rats. Psychopharmacology, 231: 899-907.

Bayless, D.W., Darling, J.S. & Daniel, J.M. (2013). Mechanisms by which neonatal testosterone exposure mediates sex differences in impulsivity in prepubertal rats. Hormones and Behavior: 64: 764-769.

Daniel, J.M. (2013). Estrogens, estrogen receptors and female cognitive aging: Impact of timing. Invited review in Special Issue, Hormones & Neurotrauma, Hormones and Behavior, 63: 231-237.

Witty, C.F., Gardella, L.P., Perez, M.C. & Daniel, J.M. (2013). Short-term estradiol administration in aging ovariectomized rats provides lasting benefits for memory and the hippocampus: a role for insulin-like growth factor-I. Endocrinology, 154: 842-852.

Witty, C.F., Foster, T.C., Semple-Rowland, S.L. & Daniel, J.M. (2012). Increasing hippocampal estrogen receptor alpha levels via viral vectors increases MAP kinase activation and enhances memory in aging rats in the absence of ovarian estrogens. PLOS ONE, 7(12):e51385.

Nelson, B.S., Witty, C.F., Williamson, E.A. & Daniel, J.M. (2012). A role for actin rearrangement in object placement memory in female rats. Neurobiology of Learning and Memory, 98: 284-90.

Bayless, D.W., Darling, J.S., Stout, W.J. & Daniel, J.M. (2012). Sex differences in attentional processes in adult rats as measured by performance on the 5-choice serial reaction time task. Behavioural Brain Research, 235: 48-54.