Vecihi Batuman, MD, FASN
Professor
Education & Affiliations
Biography
Dr. Batuman received his MD from Hacettepe University Medical School in Ankara, Turkey, and completed his Internal Medicine and Nephrology training at Jersey City Medical Center, New Jersey Medical School. He was a full-time faculty member and Chief of the Renal Hypertension program in East Orange Veterans Affairs Medical Center before he joined the Tulane Program. He served as the President of the New Jersey Society of Nephrology in 1982. Dr. Batuman is certified in Internal Medicine and Nephrology by the American Board of Internal Medicine and Nephrology and is recognized as Hypertension Specialist by the American Society of Hypertension. He is a Fellow of the American College of Physicians and a member of many professional societies including the American Society of Nephrology, International Society of Nephrology and American Society of Hypertension. His current laboratory research focuses on myeloma light chain metabolism and toxicity in kidney cells, endocytic receptors that mediate endocytosis and metabolism of filtered myeloma proteins in the kidney and the role of cytokines and transcription factors in the pathogenesis of kidney disease in myeloma. Dr. Batuman's other research interests include hypertension, lead nephropathy, Balkan endemic nephropathy, environmental kidney disease and dialysis.
Contributions
Peer Reviewed
Thethi TK, Batuman V. Challenging the conventional wisdom on diabetic nephropathy: Is microalbuminuria the earliest event? J Diabetes Complications. 2019 Mar; 33(3): 191-192. doi: 10.1016/j.jdiacomp.2018.12.006. Epub 2019 Dec 14.
Leung N, Bridoux F, Batuman V, Chaidos A, Cockwell P, D'Agati VD, Dispenzieri A, Fervenza FC, Fermand JP, Gibbs S, Gillmore JD, Herrera GA, Jaccard A, Jevremovic D, Kastritis E, Kukreti V, Kyle RA, Lachmann HJ, Larsen CP, Ludwig H, Markowitz GS, Merlini G, Mollee P, Picken MM, Rajkumar VS, Royal V, Sanders PW, Sethi S, Venner CP, Voorhees PM, Wechalekar AD, Weiss BM, Nasr SH. The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group. Nat Rev Nephrol. 2019 Jan; 15(1):45-59. doi: 10.1038/s41581-018-0077-4. Review Erratum in Nat Rev Nephrology. 2019 Feb; 15(2):121.
Bokhari SR, Siriki R, Teran FJ, Batuman V. Fatal Hypermagnesemia Due to Laxative Use. Am J Med Sci. 2018 Apr; 355(4):390-395. doi: 10.1016/j.amjms.2017.08.013. Epub 2017 Sept 12. Review.
Sirac C, Herrera GA, Sanders PW, Batuman V, Bender S, Ayala MV, Javaugue V, Teng J, Turbat-Herrera EA, Cogne M, Touchard G, Leung N, Bridoux F. Animal models of monoclonal immunoglobulin-related renal diseases. Nat Rev Nephrol. 2018 Apr;14(4):246-264. doi: 10.1038/nrneph.2018.8. Epub 2018 Feb 19. Review.
Kurella Tamura M, Vittinghoff E, Yang J, Go AS, Selinger SL, Kusek JW, Lash J, Cohen DL, Simon J, Batuman V, Ordonex J, Makos G, Yaffe K. Anemia and risk for cognitive decline in chronic kidney disease. BMC Nephrol. 2016 Jan 28; 17:13. doi: 10.1186/s12882-016-0226.6.
Doshi M, Lahoti A, Danesh FR, Batuman V, Sanders PW, American Society of Nephrology Onco-Nephrology Forum. Paraprotein-Related Kidney Disease: Kidney Injury from Paraproteins-What Determines the Site of the Injury? Clin J Am Soc Nephrol. 2016 Dec 7; 11(12):2288-2294. Epub 2016 Aug 15. Review.
Baudy A, Batuman V. Non-diabetic renal disease in diabetic patients: How to identify? When to biopsy? Journal of Diabetes and Its Complications. 2015 April 25. PMID: 25957005.
Lee BT, Ahmed FA, Hamm LL, Teran FJ, Chen CS, Liu Y, Shah K, Rifai N, Batuman V, Simon EE, He J, Chen J. Association of C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 with chronic kidney disease. BMC Nephrol. 2015; 16(1):77. PMID: 26025192.
Batuman V, Wedeen RP. The persistence of chronic lead nephropathy. Am J Kidney Dis. 2014 Jul; 64(1):1-3. PMID 24954451.
Batuman V. Sodium and Cardiovascular Disease. N Engl J Med. 2014 Nov 27;371(22):2134-9. PMID: 25427119.
Maesaka JK, Sodam B, Palaia T, et. al. Prostaglandin D2 synthase: Apoptotic factor in Alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia. Journal of nephropathology. Jul 2013;2(3):166-180.
Hanjangsit K, Dimitrov PS, Zhang H, et. al. Incidence and predictive factors of Balkan endemic nephropathy: a longitudinal study. Saudi Journal of Kidney Diseases and Transplantation: an Offical Publication of the Saudi Center for Organ Transplantation, Saudi Arabia. Mar 2014;25(2):343-352.
Khan AM, Maderdrut J, Li M, Toliver H, Coy D, Simon E, Batuman V. Pituitary adenylate cyclase-activating polypeptide prevents contrast-induced nephropathy in a novel mouse model. Physiological Reports. 19 Nov 2013. doi:10.1002/phy2.163.
Batuman V. Salt and hypertension. Why is there still a debate? Kidney inter., Suppl. 3: 316-320; doi:10.1038/kisup.2013.66.
Sengul S. Erdem Y, Batuman V, Erturk S. Hypertension and chronic kidney disease in Turkey. Kidney inter., Suppl. 3: 308-311; doi:10.1038/kisup.2013.64.
Zhang R, Li M, Chouhan KK, Simon EE, Hamm LL, Batuman V. Urine free light chains as a novel biomarker of acute kidney allograft injury. Clin Transplant. 2013 Nov; 27(6):953-60. doi:10.1111/ctr.12271. Epub 2013 Oct 26. PMID: 24304377.
Sengul S, Erturk S, Khan AM, Batuman V. Receptor-Associated Protein Blocks Internalization and Cytotoxicity of Myeloma Light Chain in Cultured Human Proximal Tubular Cells. PLoS ONE 8(7):e70276. doi:10.1371/journal.pone.0070276.
Maesaka JK, Sodam B, Palaia T, Ragolia L, Batuman V, Miyawaki N, Shastry S, Youmans S, El-Saban M. Prostaglandin D2 synthase: Apoptotic factor in alzheimer plasma, inducer of reactive oxygen species, inflammatory cytokines and dialysis dementia. J Nephropathology. 2013;2(3): 166-180. doi: 10.5812/nephropathol.10732.
Batuman V. Salt and Hypertension: An Evolutionary Perspective. J Hypertens 1:e106. http://dx.doi.org/10.4172/2167-1095.1000e106.
Khan AM, Li M, Abdulnour-Nakhoul S, Maderdrut JL, Simon E, Batuman V. Delayed administration of pituitary adenylate cyclase-activating polypeptide 38 ameliorates renal ischemia/reperfusion injury in mice by modulating Toll-like receptors. Peptides, 2012.
Batuman V. The pathogenesis of acute kidney impairment in patients with multiple myeloma. Adv Chronic Kidney Dis. 2012; 19(5):282-6.
Lukitsch I, Kehr J, Chaykovska L, Wallukat G, Nieminen-Kelha M, Batuman V, et al. Renal Ischemia and Transplantation Predispose to Vascular Constriction Mediated by Angiotensin II Type 1 Receptor-Activating Antibodies. Transplantation. 2012; 94(1):8-13.
Hanjansit K, Karmaus W, Dimitrov P, Zhang H, Burch J, Tzolova S, Batuman V. The role of a parental history of Balkan endemic nephropathy in the occurrence of BEN: a prospective study. International Journal of Nephrology and Renovascular Disease, 2012, 5:61-68.
Mills KT, Kobori H, Hamm LL, Alper AB, Khan IE, Rahman M, et. al. Increased urinary excretion of angiotensinogen is associated with risk of chronic kidney disease. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association. 2012; 27(8):3176-81.
Hutchinson CA, Batuman V, Behrens J, et al. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol. 2011; 8(1):43-51.
Jalandhara N, Arora R, Batuman V. Nephrogenic Systemic Fibrosis and Gadolinium-Contraining Radiological Contrast Agents: An Update. Clin Pharmacol Ther 2011; 89: 920-923.
Khan AM, Li M, Brant E, Maderdrut JL, Majid DS, Simon EE, Batuman V. Renoprotection with Pituitary Adenylate Cyclase-Activating Polypeptide in Cyclosporine A-Induced Nephrotoxicity. Journal of Investigative Medicine 2011; 59:793-802.
Li M, Balamuthusamy S, Khan AM, Maderdrut JL, Simon EE, Batuman V. Pituitary adenylate cyclase-activating polypeptide prevents Cisplatin-induced renal failure. J Mol Neurosci 43(2011), pp.58-66.
Nakhoul N, Batuman V. Role of proximal tubules in the pathogenesis of kidney disease. Contrib Nephrol 169 (2011), pp. 37-50.
Book/Book Chapter
Batuman V and Lerma, eds. Diabetes and Kidney Disease. New York/Heidelberg/Dordrecht/London, Springer 2014.
