Dr. Olan Jackson-Weaver joined our Department of Surgery in September 2018 as a Research Assistant Professor in the Division of Trauma and Acute Care Education. He was born and raised in Albuquerqe, New Mexico. After completing his Bachelors degrees in Chemistry and Biology and his Ph.D. in Biomedical Sciences (vascular physiology focus) from the University of New Mexico, He received postdoctoral training at the University of California Los Angeles and the University of Southern California studying astrocyte calcium signaling and the roles of protein arginine methylation in heart development and disease. His lab at Tulane University studies several aspects of endothelial cell biology, including endothelial cell damage during shock and trauma and the role of Ca2+ signaling modalities in the regulation of angiogenesis.
Our lab is interested in the roles of endothelial calcium signaling in hemorrhagic shock, ischemia-reperfusion injury, acute lung injury, and angiogenesis. We are currently focusing on the role of mitochondrial reactive oxygen species in regulating endothelial calcium signaling in these disease states, and how the proteoglycan surface layer of the endothelium can be damaged by this signaling mechanism. The endothelium is vital in maintaining hemodynamic, coagulation, tissue fluid, and inflammatory homeostasis. These pathways are all affected by ischemia-reperfusion events such as...
Endothelial Cell Biology
Protein Arginine Methylation
Click here to read Dr. Jackson-Weaver's publications on PubMed.