Donald Krogstad, MD

Dr. Krogstad received his undergraduate degree from Bowdoin College in Brunswick, Maine. He received his M.D. in 1969 from Harvard Medical School. After training at the Massachusetts General Hospital in Boston, he served at the Centers for Disease Control in Atlanta in Parasitic Diseases and as a Peace Corps Volunteer Physician in Lilongwe, Malawi. After serving at the Washington University School of Medicine for 14 years, Dr. Krogstad joined the Tulane faculty in June 1992 as Chair of Tropical Medicine, was invested as the Henderson Professor in 1994, and appointed Director of the Center for Infectious Diseases in 1998. Dr. Krogstad's current research is aimed at the molecular and genetic bases of resistance to chloroquine and quinine, structure-activity relationships among antimalarials, the development of a transfection system in Plasmodium falciparum and the use of plasmid constructs with a proline-rich amino acid linker to enhance the immunogenicity of cloned malaria parasite antigens. Field studies are centered in Mali and focus on three issues: optimal strategies for the use of chloroquine, techniques for the characterization of individual clones from polyclonal field isolates, and the development of methods to study pathogenicity and parasite virulence.