Gang Liu, Ph.D.

Instructor

School of Medicine
Department
Pathology Laboratory Medicine
Gang Liu

Education & Affiliations

2023 – Present Instructor, Department of Pathology & Laboratory Medicine, School of Medicine, Tulane University, USA.
2020 – 2023 Postdoctoral Research Fellow, Department of Pathology & Laboratory Medicine, School of Medicine, Tulane University, USA.
2018 – 2020 Postdoctoral Research Fellow, Department of Pathology & Laboratory Medicine, School of Medicine, Indiana University, USA.
2017 – 2018 Postdoctoral Research Fellow, Department of Biological Sciences, College of Bioscience and Biotechnology, Yangzhou University, China.

Research

  1. The production and function of extracellular vesicles under autophagy deficient condition (Mentor: Prof. Xiao-Ming Yin).
  2. Chaperone-mediated autophagy (CMA) rescues macroautophagy deficiency induced liver dysfunction (Mentor: Prof. Xiao-Ming Yin).
  3. Transcription factor Foxo3 mediates mitophagy in cadmium-induced kidney disease (Past)

Contributions

  1. Liu G and Yin Xiao-Ming. (2022) The Role of Extracellular Vesicles in Liver Pathogenesis. Am J Pathol 192(10):1358-1367.
  2. Huda N, Khambu B, Liu G, …, Yin XM. (2022) Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver. Cell Mol Gastroenterol Hepatol 14(2):333-355.
  3. Byrnes K, …, Liu G, Yin XM, Khambu B. (2023) Impaired hepatic autophagy exacerbates hepatotoxin induced liver injury. Cell Death Discov 21;9(1):71.
  4. Khambu B, Hong H, Liu S, Liu G, …, Yin XM. (2020) The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors. Cell Death Dis 11(5):333.
  5. Nuda N, Liu G, …, Yin XM. (2019) Hepatic senescence, the good and the bad. World J Gastroenterol 25(34): 5069-5081.
  6. Liu WJ, …, Liu G#, et al. (2022) Paeonol protects renal tubular cells against cadmium-induced cytotoxicity via alleviating oxidative stress, inhibiting inflammatory responses and restoring autophagy. J Inorg Biochem 230:111733. # Co-corresponding author
  7. Dong WX, Liu G#, et al. (2021) Cadmium exposure induces rat proximal tubular cells injury via p62-dependent Nrf2 nucleus translocation mediated activation of AMPK/AKT/mTOR pathway. Ecotoxicol Environ Saf 214:112058. # Co-corresponding author
  8. Chen SH, Liu G#, et al. (2018) Alpha lipoic acid attenuates cadmium-induced nephrotoxicity via the mitochondrial apoptotic pathways in rat. J Inorg Biochem 184: 19-26. # Co-corresponding author
  9. Liu G, Yuan Y, Long MF, et al. (2017) Beclin-1-mediated autophagy protects against cadmium-activated apoptosis via the Fas/FasL pathway in primary rat proximal tubular cell culture. SCI REP 7: 977.
  10. Liu G, Wang ZK, Wang ZY, et al. (2016) Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead. Arch Toxicol 90(5):1193-209.